2023
Cystic fibrosis screening, evaluation, and management of hepatobiliary disease consensus recommendations
Sellers Z, Assis D, Paranjape S, Sathe M, Bodewes F, Bowen M, Cipolli M, Debray D, Green N, Hughan K, Hunt W, Leey J, Ling S, Morelli G, Peckham D, Pettit R, Philbrick A, Stoll J, Vavrina K, Allen S, Goodwin T, Hempstead S, Narkewicz M. Cystic fibrosis screening, evaluation, and management of hepatobiliary disease consensus recommendations. Hepatology 2023, 79: 1220-1238. PMID: 37934656, PMCID: PMC11020118, DOI: 10.1097/hep.0000000000000646.Peer-Reviewed Original ResearchConceptsAdvanced liver diseaseCystic fibrosisLiver diseaseHepatobiliary involvementHepatobiliary complicationsCF-associated liver diseasePubMed literature searchCystic fibrosis screeningScreening ultrasoundPortal hypertensionOutcome questionsLiver biopsyLiver failureMultilobular cirrhosisFibrosis screeningConsensus recommendationsFull-text reviewHepatobiliary diseaseCF FoundationLiterature searchThirty-oneCF outcomesMultidisciplinary committeeDiseaseComplications
2022
Update in Advancing the Gastrointestinal Frontier in Cystic Fibrosis
Vélez C, Freedman S, Assis D. Update in Advancing the Gastrointestinal Frontier in Cystic Fibrosis. Clinics In Chest Medicine 2022, 43: 743-755. PMID: 36344078, DOI: 10.1016/j.ccm.2022.07.001.Peer-Reviewed Original Research
2018
Chronic Complications of Cholestasis Evaluation and Management
Assis DN. Chronic Complications of Cholestasis Evaluation and Management. Clinics In Liver Disease 2018, 22: 533-544. PMID: 30259851, DOI: 10.1016/j.cld.2018.03.014.BooksMeSH KeywordsAbsorptiometry, PhotonAvitaminosisBone Density Conservation AgentsBone Diseases, MetabolicCarcinoma, HepatocellularCholestasisDiet, HealthyEarly Detection of CancerEsophageal and Gastric VaricesExerciseFibric AcidsGastrointestinal HemorrhageHumansHydroxymethylglutaryl-CoA Reductase InhibitorsHyperlipidemiasHypertension, PortalLiver Cirrhosis, BiliaryLiver NeoplasmsMass ScreeningOsteoporosisOsteoporotic FracturesVitamin A DeficiencyVitamin D DeficiencyVitamin E DeficiencyVitamin K DeficiencyConceptsPrimary biliary cholangitisChronic cholestasisFat-soluble vitamin deficiencyEarly-stage diseaseMetabolic bone diseaseCardiovascular eventsChronic complicationsPortal hypertensionBiliary cholangitisVitamin deficiencyBone diseaseLong-term effectsNotable riskCholestasisComplicationsPatientsPractical managementDiseaseRiskHarmful consequencesCholangitisHypertensionHyperlipidemiaOsteoporosisTherapy
2017
Gallbladder and bile duct disease in Cystic Fibrosis
Assis DN, Debray D. Gallbladder and bile duct disease in Cystic Fibrosis. Journal Of Cystic Fibrosis 2017, 16: s62-s69. PMID: 28986023, DOI: 10.1016/j.jcf.2017.07.006.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsBile duct diseaseCystic fibrosisHigh-quality careDuct diseaseExtra-pulmonary manifestationsBile duct pathologyEfficient clinical evaluationHepatobiliary disturbancesCommon complicationClinical presentationBiliary diseaseDuct pathologyBiliary treeClinical evaluationBiliary disordersUndetected pathologyGallbladderDiverse disordersPatientsDiseaseCareFibrosisPathologyDisordersComplications
2015
Gastrointestinal Disorders in Cystic Fibrosis
Assis DN, Freedman SD. Gastrointestinal Disorders in Cystic Fibrosis. Clinics In Chest Medicine 2015, 37: 109-118. PMID: 26857772, DOI: 10.1016/j.ccm.2015.11.004.BooksConceptsCystic fibrosisDistal intestinal obstruction syndromeCommon GI complicationsIntestinal obstruction syndromeCare of patientsGI complicationsGastrointestinal manifestationsObstruction syndromeGI disordersGI malignanciesIntestinal overgrowthPulmonary functionClinical presentationGastrointestinal disordersPancreatic insufficiencyInnovative therapiesRecent approvalModulating agentsFibrosisDisordersComplicationsPatientsMalignancySyndromeTherapy
2012
Successful Treatment of a Bleeding Umbilical Varix by Percutaneous Umbilical Vein Embolization With Sclerotherapy
Assis DN, Pollak J, Schilsky ML, Emre S. Successful Treatment of a Bleeding Umbilical Varix by Percutaneous Umbilical Vein Embolization With Sclerotherapy. Journal Of Clinical Gastroenterology 2012, 46: 115-118. PMID: 21897280, DOI: 10.1097/mcg.0b013e31822b7f9a.Peer-Reviewed Case Reports and Technical NotesConceptsUmbilical varixEctopic varicesVein embolizationSuccessful treatmentEctopic variceal bleedingLife-threatening complicationsChallenging clinical dilemmaNew therapeutic optionsVariceal bleedingAcute presentationPortal hypertensionTherapeutic optionsClinical dilemmaVaricesUnreported techniqueExternal hemorrhageBleedingSclerotherapyEmbolizationRare sourceTreatmentHypertensionComplicationsHemorrhagePatients
2010
Testing and management of thrombocytopenia and coagulopathy in the pre- and postliver transplant patient.
Assis DN, Schilsky ML. Testing and management of thrombocytopenia and coagulopathy in the pre- and postliver transplant patient. Minerva Gastroenterology 2010, 56: 331-43. PMID: 21037549.Peer-Reviewed Original ResearchConceptsPost-transplant periodLiver diseaseAdvanced liver diseaseManagement of coagulopathyAcute liver failureManagement of thrombocytopeniaImportant clinical skillSuperimposed complicationsHepatic dysfunctionTransplant patientsLiver failureCoagulation changesTransplant periodPathophysiologic changesBlood productsCoagulation testingCoagulopathyThrombocytopeniaPatientsClinical skillsDiseasePreSepsisComplicationsDysfunction