2018
Cardiac Hypertrophy: Signaling and Cellular Crosstalk
Tirziu D. Cardiac Hypertrophy: Signaling and Cellular Crosstalk. 2018 DOI: 10.1016/b978-0-12-801238-3.99834-9.Peer-Reviewed Original ResearchCardiac hypertrophyHypertrophic responseHemodynamic stressMolecular basisPathological hypertrophic responsesCellular crosstalkVariety of stimuliMyocardial infarctionImmune cellsCardiac performanceHypertrophic growthChronic increaseVascular cellsPhysiological stimuliCellular communicationMajor playersCardiac cellsWall stressHypertrophyCellsCrosstalkCardiomyocytesPrimary mechanismSignalingStressCardiac Hypertrophy: Signaling and Cellular Crosstalk
Tirziu D. Cardiac Hypertrophy: Signaling and Cellular Crosstalk. 2018, 434-450. DOI: 10.1016/b978-0-12-809657-4.99834-x.Peer-Reviewed Original ResearchCardiac hypertrophyHypertrophic responseHemodynamic stressMolecular basisPathological hypertrophic responsesCellular crosstalkVariety of stimuliMyocardial infarctionImmune cellsCardiac performanceHypertrophic growthChronic increaseVascular cellsPhysiological stimuliCellular communicationMajor playersCardiac cellsWall stressHypertrophyCellsCrosstalkCardiomyocytesPrimary mechanismSignalingStress
2007
Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice
Tirziu D, Chorianopoulos E, Moodie KL, Palac RT, Zhuang ZW, Tjwa M, Roncal C, Eriksson U, Fu Q, Elfenbein A, Hall AE, Carmeliet P, Moons L, Simons M. Myocardial hypertrophy in the absence of external stimuli is induced by angiogenesis in mice. Journal Of Clinical Investigation 2007, 117: 3188-3197. PMID: 17975666, PMCID: PMC2045601, DOI: 10.1172/jci32024.Peer-Reviewed Original ResearchMeSH KeywordsAngiogenic ProteinsAnimalsCardiomegalyCells, CulturedEchocardiographyEndothelial CellsEnzyme InhibitorsHeartHemodynamicsMiceMice, Inbred C57BLMice, TransgenicMyocardiumMyocytes, CardiacNeovascularization, PhysiologicNG-Nitroarginine Methyl EsterOrgan SizeRatsRats, Sprague-DawleyTransgenesConceptsMyocardial hypertrophyHeart sizeNormal heart sizeENOS inhibitor L-NAMEInhibitor L-NAMEAtrial natriuretic factorHypertrophic marker expressionNormal adult mouse heartAdult mouse heartAngiogenic growth factorsL-NAMEBeta-MHCCardiac massMyocardial infarctionMyocardial functionNatriuretic factorCardiac performanceCardiomyocyte sizeTransgenic miceStimulation periodHeart growthHypertrophy markersMarker expressionMouse heartsMurine heart