On the outside, looking in: A review and evaluation of the comparability of blood and brain “‐omes”
Tylee DS, Kawaguchi DM, Glatt SJ. On the outside, looking in: A review and evaluation of the comparability of blood and brain “‐omes”. American Journal Of Medical Genetics Part B Neuropsychiatric Genetics 2013, 162: 595-603. PMID: 24132893, DOI: 10.1002/ajmg.b.32150.Peer-Reviewed Original ResearchConceptsCpG island methylation levelsCross-tissue correlationBlood-based biomarker studiesTranscriptomic studiesDNA methylationOmics analysisGene expressionMethylation levelsBlood tissue samplesExpression levelsProtein expressionProfiling methodExpressionEpigenomeTranscriptomeProteomeGenesMethylationTranscriptsTissue samplesValidation of biomarkersBetter understandingCritical precursorPatternsParticular subset