2012
Orosensory and Homeostatic Functions of the Insular Taste Cortex
de Araujo IE, Geha P, Small DM. Orosensory and Homeostatic Functions of the Insular Taste Cortex. Chemosensory Perception 2012, 5: 64-79. PMID: 25485032, PMCID: PMC4254792, DOI: 10.1007/s12078-012-9117-9.Peer-Reviewed Original ResearchInsular cortexCortex functionTaste-responsive regionsWeight gain susceptibilityCentral taste pathwaysInsular taste cortexTaste cortexTaste pathwaysCurrent evidenceNeuronal responsesHomeostatic roleChemosensory inputIntegrative circuitsBrain circuitsHomeostatic functionsCurrent experimental evidenceCortexVisual stimulationIngestive behaviorNutritional statePotential roleInsular areasFunctional mapsSensory modalitiesSomatosensory
2011
Modality-Specific Neural Effects of Selective Attention to Taste and Odor
Veldhuizen MG, Small DM. Modality-Specific Neural Effects of Selective Attention to Taste and Odor. Chemical Senses 2011, 36: 747-760. PMID: 21685407, PMCID: PMC3175104, DOI: 10.1093/chemse/bjr043.Peer-Reviewed Original ResearchConceptsPrimary olfactory cortexPrimary taste cortexAnterior insular cortexInsular cortexOlfactory cortexTaste cortexPrimary gustatory cortexFunctional magnetic resonancePrimary olfactoryGustatory cortexModality-specific activationInsular responsesNeural effectsCortexBrain responsesMultimodal regionsTaste perceptionMagnetic resonanceGeneral effectSelective attentionActivationResponse
2010
Taste representation in the human insula
Small DM. Taste representation in the human insula. Brain Structure And Function 2010, 214: 551-561. PMID: 20512366, DOI: 10.1007/s00429-010-0266-9.Peer-Reviewed Original ResearchConceptsInsular cortexTaste cortexTaste representationsUnimodal sensory corticesPrimary taste cortexHuman insular cortexAnterior insular cortexHuman insulaInterspecies differencesSensory cortexSense of tasteCortexFeeding behaviorSensory regionsSignificant interspecies differencesCritical relayPrimary aimMonkeysHumansThe Insular Taste Cortex Contributes to Odor Quality Coding
Veldhuizen MG, Nachtigal D, Teulings L, Gitelman DR, Small DM. The Insular Taste Cortex Contributes to Odor Quality Coding. Frontiers In Human Neuroscience 2010, 4: 58. PMID: 20700500, PMCID: PMC2917218, DOI: 10.3389/fnhum.2010.00058.Peer-Reviewed Original ResearchCommon central mechanismInsular taste cortexTaste cortexCentral mechanismsFood odorsNon-food odorsOdor quality codingOlfactory cortexInsular cortexOlfactory stimulationCortexCentral pathwaysCortex contributesSweet tasteGustatory systemOlfactory stimuliInsulaStimulationDiscrete mechanismsSensationTaste qualityQuality codingOdor sweetnessPiriformSweetness ratings
2009
Neural correlates of evaluative compared with passive tasting
Bender G, Veldhuizen MG, Meltzer JA, Gitelman DR, Small DM. Neural correlates of evaluative compared with passive tasting. European Journal Of Neuroscience 2009, 30: 327-338. PMID: 19614981, PMCID: PMC2776645, DOI: 10.1111/j.1460-9568.2009.06819.x.Peer-Reviewed Original ResearchConceptsLateral orbitofrontal cortexOrbitofrontal cortexPrimary taste cortexLeft lateral orbitofrontal cortexFunctional magnetic resonanceTasteless solutionMaximal responseTaste cortexFunction of taskCortical representationGustatory informationAnterior insulaVentral regionNeural responsesPreferential connectivityAmygdalaNeural correlatesCortexInsulaNeural encodingSubjectsStimulus presenceMagnetic resonanceResponseEarly relay
2007
Trying to Detect Taste in a Tasteless Solution: Modulation of Early Gustatory Cortex by Attention to Taste
Veldhuizen MG, Bender G, Constable RT, Small DM. Trying to Detect Taste in a Tasteless Solution: Modulation of Early Gustatory Cortex by Attention to Taste. Chemical Senses 2007, 32: 569-581. PMID: 17495173, DOI: 10.1093/chemse/bjm025.Peer-Reviewed Original Research
1997
A Role for the Right Anterior Temporal Lobe in Taste Quality Recognition
Small D, Jones-Gotman M, Zatorre R, Petrides M, Evans A. A Role for the Right Anterior Temporal Lobe in Taste Quality Recognition. Journal Of Neuroscience 1997, 17: 5136-5142. PMID: 9185551, PMCID: PMC6573307, DOI: 10.1523/jneurosci.17-13-05136.1997.Peer-Reviewed Original ResearchConceptsRegional cerebral blood flowAnteromedial temporal lobeGroup of patientsTemporal lobeRight anterior temporal lobectomyOrbitofrontal cortexCaudolateral orbitofrontal cortexAnterior temporal lobectomyCerebral blood flowRight anterior temporal lobePrimary taste cortexTreatment of epilepsyPositron emission tomographyRight cerebral hemisphereAnterior temporal lobeRCBF increasesTemporal lobectomyGustatory functionTaste cortexBlood flowCerebral hemispheresControl groupEmission tomographyPatientsTaste sensation