2019
Prognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance
Quail M, Grunseich K, Baldassarre LA, Mojibian H, Marieb MA, Cornfeld D, Soufer A, Sinusas AJ, Peters DC. Prognostic and functional implications of left atrial late gadolinium enhancement cardiovascular magnetic resonance. Journal Of Cardiovascular Magnetic Resonance 2019, 21: 2. PMID: 30602395, PMCID: PMC6317232, DOI: 10.1186/s12968-018-0514-3.Peer-Reviewed Original ResearchConceptsLA late gadolinium enhancementNew-onset atrial arrhythmiasLate gadolinium enhancementAtrial arrhythmiasAtrial late gadolinium enhancementLA functionAtrial fibrillationGadolinium enhancementCardiovascular magnetic resonance imagingNew atrial arrhythmiasPoor procedural outcomesLV diastolic functionLA ejection fractionVentricular mechanical functionCardiovascular magnetic resonanceMagnetic resonance imagingSeptal eDiastolic functionEjection fractionHazard ratioLA volumeProcedural outcomesPrognostic biomarkerCardiac diseasePrior history
2016
CMR-Verified Lower LA Strain in the Presence of Regional Atrial Fibrosis in Atrial Fibrillation
Peters DC, Duncan JS, Grunseich K, Marieb MA, Cornfeld D, Sinusas AJ, Chelikani S. CMR-Verified Lower LA Strain in the Presence of Regional Atrial Fibrosis in Atrial Fibrillation. JACC Cardiovascular Imaging 2016, 10: 207-208. PMID: 27085430, PMCID: PMC5600154, DOI: 10.1016/j.jcmg.2016.01.015.Peer-Reviewed Original Research
2014
Cardiovascular Magnetic Resonance Imaging of Scar Development Following Pulmonary Vein Isolation: A Prospective Study
Hsing J, Peters DC, Knowles BR, Manning WJ, Josephson ME. Cardiovascular Magnetic Resonance Imaging of Scar Development Following Pulmonary Vein Isolation: A Prospective Study. PLOS ONE 2014, 9: e104844. PMID: 25251403, PMCID: PMC4174508, DOI: 10.1371/journal.pone.0104844.Peer-Reviewed Original ResearchMeSH KeywordsAdultAtrial FibrillationCardiovascular SystemCatheter AblationCicatrixContrast MediaEdemaFemaleGadolinium DTPAHumansImage EnhancementLinear ModelsMagnetic Resonance ImagingMaleMiddle AgedProspective StudiesPulmonary VeinsRadiographyReproducibility of ResultsSensitivity and SpecificityTime FactorsConceptsPulmonary vein isolationCardiovascular magnetic resonanceVein isolationAtrial wall thicknessLGE enhancementLGE volumeCardiovascular magnetic resonance imagingVolume of LGEAtrial fibrillation patientsPattern of edemaSubsequent scar formationLate gadolinium enhancement (LGE) imagingMagnetic resonanceAtrial wall thickeningNon-invasive assessmentMagnetic resonance imagingEdema enhancementFibrillation patientsProspective studyPost ablationEarly edemaLGE scarScar formationEdemaResonance imaging
2013
Left atrial late gadolinium enhancement with water–fat separation: The importance of phase‐encoding order
Shaw JL, Knowles BR, Goldfarb JW, Manning WJ, Peters DC. Left atrial late gadolinium enhancement with water–fat separation: The importance of phase‐encoding order. Journal Of Magnetic Resonance Imaging 2013, 40: 119-125. PMID: 24105717, PMCID: PMC5036388, DOI: 10.1002/jmri.24340.Peer-Reviewed Original ResearchMeSH KeywordsAdipose TissueAlgorithmsAtrial FibrillationBody WaterContrast MediaFemaleGadoliniumHeart AtriaHumansImage EnhancementImage Interpretation, Computer-AssistedMagnetic Resonance ImagingMaleMiddle AgedMyocardial StunningPreoperative CarePulmonary VeinsReproducibility of ResultsSensitivity and SpecificitySignal Processing, Computer-AssistedSubtraction TechniqueConceptsWater-fat separationAortic injury is common following pulmonary vein isolation
Tung P, Hong SN, Chan RH, Peters DC, Hauser TH, Manning WJ, Josephson ME. Aortic injury is common following pulmonary vein isolation. Heart Rhythm 2013, 10: 653-658. PMID: 23318348, DOI: 10.1016/j.hrthm.2013.01.012.Peer-Reviewed Original ResearchConceptsPulmonary vein isolationVein isolationAortic blood poolPercent of patientsNumber of patientsCardiac magnetic resonanceLate gadolinium enhancementSignificant increaseAortic injuryEsophageal injuryAortic enhancementMediastinal structuresGadolinium enhancementPatientsControl groupAortaClinical implicationsHyperenhancementMean signal intensityBlood poolLGELatter groupLA enhancementInjuryLarger LAEvaluation of current algorithms for segmentation of scar tissue from late Gadolinium enhancement cardiovascular magnetic resonance of the left atrium: an open-access grand challenge
Karim R, Housden RJ, Balasubramaniam M, Chen Z, Perry D, Uddin A, Al-Beyatti Y, Palkhi E, Acheampong P, Obom S, Hennemuth A, Lu Y, Bai W, Shi W, Gao Y, Peitgen HO, Radau P, Razavi R, Tannenbaum A, Rueckert D, Cates J, Schaeffter T, Peters D, MacLeod R, Rhode K. Evaluation of current algorithms for segmentation of scar tissue from late Gadolinium enhancement cardiovascular magnetic resonance of the left atrium: an open-access grand challenge. Journal Of Cardiovascular Magnetic Resonance 2013, 15: 105. PMID: 24359544, PMCID: PMC3878126, DOI: 10.1186/1532-429x-15-105.Peer-Reviewed Original ResearchConceptsRadio-frequency catheter ablationAtrial fibrillationTreatment of AFEnhancement cardiovascular magnetic resonance imagingLate gadolinium enhancement cardiovascular magnetic resonanceReference standardEnhancement cardiovascular magnetic resonanceCardiovascular magnetic resonance imagingPost-ablation imagesRegions of fibrosisAssessment of treatmentCardiovascular magnetic resonanceMagnetic resonance imagingPost-ablation imagingLA fibrosisCatheter ablationLGE CMR imagesCMR imagesLeft atriumTreatment stratificationScar tissueResonance imagingFibrosisStandardised evaluationKing's College London
2012
Respiratory bellows‐gated late gadolinium enhancement of the left atrium
Peters DC, Shaw JL, Knowles BR, Moghari MH, Manning WJ. Respiratory bellows‐gated late gadolinium enhancement of the left atrium. Journal Of Magnetic Resonance Imaging 2012, 38: 1210-1214. PMID: 23197465, PMCID: PMC3812253, DOI: 10.1002/jmri.23954.Peer-Reviewed Original ResearchConceptsRight inferior pulmonary veinLate gadolinium enhancementRight superior PVAtrial fibrillationGadolinium enhancementRespiratory compensationScar presenceInferior pulmonary veinNav gatingPresence of scarAtrial imagingSuperior PVBlinded gradingPulmonary veinsLeft atriumTrue scarsPatientsQuadrantScarImproved assessmentFibrillationAtrium
2011
Pulmonary vein inflow artifact reduction for free‐breathing left atrium late gadolinium enhancement
Moghari MH, Peters DC, Smink J, Goepfert L, Kissinger KV, Goddu B, Hauser TH, Josephson ME, Manning WJ, Nezafat R. Pulmonary vein inflow artifact reduction for free‐breathing left atrium late gadolinium enhancement. Magnetic Resonance In Medicine 2011, 66: 180-186. PMID: 21360738, PMCID: PMC3120912, DOI: 10.1002/mrm.22769.Peer-Reviewed Original Research
2010
Noncontrast SSFP pulmonary vein magnetic resonance angiography: Impact of off‐resonance and flow
Hu P, Stoeck CT, Smink J, Peters DC, Ngo L, Goddu B, Kissinger KV, Goepfert LA, Chan J, Hauser TH, Rofsky NM, Manning WJ, Nezafat R. Noncontrast SSFP pulmonary vein magnetic resonance angiography: Impact of off‐resonance and flow. Journal Of Magnetic Resonance Imaging 2010, 32: 1255-1261. PMID: 21031533, PMCID: PMC2975425, DOI: 10.1002/jmri.22356.Peer-Reviewed Original ResearchConceptsMagnetic resonance angiographyPulmonary veinsHealthy subjectsResonance angiographyAtrial fibrillation patientsSuperior pulmonary veinBlood flow velocityHealthy adult subjectsSignal voidVoid artifactsFibrillation patientsAF patientsPV bloodPV flowLeft atriumBlood flowAdult subjectsTrigger delaySignal void artifactsPatientsAngiographySubjectsCauseSSFP sequencePulmonaryLate Gadolinium Enhancement of the Esophagus is Common on Cardiac MR Several Months after Pulmonary Vein Isolation: Preliminary Observations
MENG J, PETERS DC, HSING JM, CHUANG ML, CHAN J, FISH A, JOSEPHSON ME, MANNING WJ. Late Gadolinium Enhancement of the Esophagus is Common on Cardiac MR Several Months after Pulmonary Vein Isolation: Preliminary Observations. Pacing And Clinical Electrophysiology 2010, 33: 661-666. PMID: 20059713, DOI: 10.1111/j.1540-8159.2009.02671.x.Peer-Reviewed Original ResearchConceptsPulmonary vein isolationCardiovascular magnetic resonance imagingAtrial fibrillationVein isolationLGE-CMRPost-pulmonary vein isolationLate gadolinium enhancement cardiovascular magnetic resonance imagingEnhancement cardiovascular magnetic resonance imagingFrequent imaging findingsLeft atrium cavityLate gadolinium enhancementMagnetic resonance imagingEsophageal positionImaging findingsEsophageal locationGadolinium enhancementHyperenhancementNoninvasive assessmentVertebral bodyResonance imagingClinical implicationsAblation siteLonger ablation timePatientsCardiac MR
2009
Relationship between intended sites of RF ablation and post-procedural scar in AF patients, using late gadolinium enhancement cardiovascular magnetic resonance
Taclas JE, Nezafat R, Wylie JV, Josephson ME, Hsing J, Manning WJ, Peters DC. Relationship between intended sites of RF ablation and post-procedural scar in AF patients, using late gadolinium enhancement cardiovascular magnetic resonance. Heart Rhythm 2009, 7: 489-496. PMID: 20122877, PMCID: PMC2843771, DOI: 10.1016/j.hrthm.2009.12.007.Peer-Reviewed Original ResearchRecurrence of Atrial Fibrillation Correlates With the Extent of Post-Procedural Late Gadolinium Enhancement A Pilot Study
Peters DC, Wylie JV, Hauser TH, Nezafat R, Han Y, Woo JJ, Taclas J, Kissinger KV, Goddu B, Josephson ME, Manning WJ. Recurrence of Atrial Fibrillation Correlates With the Extent of Post-Procedural Late Gadolinium Enhancement A Pilot Study. JACC Cardiovascular Imaging 2009, 2: 308-316. PMID: 19356576, PMCID: PMC2703450, DOI: 10.1016/j.jcmg.2008.10.016.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAtrial FibrillationCatheter AblationCicatrixContrast MediaFemaleGadolinium DTPAHeart AtriaHumansImage Interpretation, Computer-AssistedImaging, Three-DimensionalKaplan-Meier EstimateMagnetic Resonance ImagingMaleMiddle AgedPilot ProjectsPredictive Value of TestsProportional Hazards ModelsPulmonary VeinsRecurrenceRisk AssessmentTime FactorsTreatment FailureConceptsRight inferior pulmonary veinCardiac magnetic resonanceLGE cardiac magnetic resonanceRF ablation proceduresPulmonary veinsAF recurrenceAblation proceduresPV isolationLate gadolinium enhancement (LGE) CMRAtrial fibrillation correlatesBidirectional conduction blockAtrial fibrillation patientsInferior pulmonary veinExtent of scarringRadiofrequency ablation lesionsExtent of scarA Pilot StudyFirst yearRecurrent AFThirteen patientsFibrillation patientsParoxysmal AFPV ostiaProcedural successAtrial scarring
2008
Evaluating the left atrium by magnetic resonance imaging
Hauser TH, Peters DC, Wylie JV, Manning WJ. Evaluating the left atrium by magnetic resonance imaging. EP Europace 2008, 10: iii22-iii27. PMID: 18955395, PMCID: PMC2573030, DOI: 10.1093/europace/eun223.Peer-Reviewed Original ResearchMeSH KeywordsAtrial FibrillationHeart AtriaHeart Conduction SystemHumansMagnetic Resonance ImagingPulmonary VeinsSurgery, Computer-AssistedConceptsLeft atriumPulmonary veinsRecurrent atrial fibrillationAtrial fibrillation ablationMagnetic resonance imagingFibrillation ablationAtrial fibrillationVariant anatomyAblation therapyMagnetic resonance imaging methodResonance imagingAtriumVeinAnatomyCatheterFibrillationImaging methodTherapyPreventionLeft atrial function and scar after catheter ablation of atrial fibrillation
Wylie JV, Peters DC, Essebag V, Manning WJ, Josephson ME, Hauser TH. Left atrial function and scar after catheter ablation of atrial fibrillation. Heart Rhythm 2008, 5: 656-662. PMID: 18452866, DOI: 10.1016/j.hrthm.2008.02.008.Peer-Reviewed Original ResearchConceptsAtrial systolic functionLA ejection fractionAtrial fibrillationCatheter ablationEjection fractionRadiofrequency ablationLeft atriumAF ablationSystolic functionLA functionCircumferential pulmonary vein isolationMaximum RA volumeRA ejection fractionCardiovascular magnetic resonance imagingPulmonary vein isolationLA scarPersistent atrial fibrillationMaximum LA volumeCine CMR imagingScar volumeMagnetic resonance imagingThromboembolic riskAtrial functionVein isolationConsecutive patients
2007
Detection of Pulmonary Vein and Left Atrial Scar after Catheter Ablation with Three-dimensional Navigator-gated Delayed Enhancement MR Imaging: Initial Experience
Peters DC, Wylie JV, Hauser TH, Kissinger KV, Botnar RM, Essebag V, Josephson ME, Manning WJ. Detection of Pulmonary Vein and Left Atrial Scar after Catheter Ablation with Three-dimensional Navigator-gated Delayed Enhancement MR Imaging: Initial Experience. Radiology 2007, 243: 690-5. PMID: 17517928, DOI: 10.1148/radiol.2433060417.Peer-Reviewed Original ResearchConceptsPulmonary veinsLeft atriumEnhancement MR imagingLeft inferior pulmonary veinMR imagingInferior pulmonary veinEnhancement magnetic resonance imagingLocal institutional review boardUnpaired t-testMagnetic resonance imagingInstitutional review boardIsolation therapyCatheter ablationAtrial fibrillationRadiofrequency ablationInteratrial septumAtrial wallEnhancement patternPatientsInitial experienceAtrial scarResonance imagingRF ablationMR imaging methodsInformed consent
2005
Pulmonary vein imaging: comparison of 3D magnetic resonance angiography with 2D cine MRI for characterizing anatomy and size.
Syed MA, Peters DC, Rashid H, Arai AE. Pulmonary vein imaging: comparison of 3D magnetic resonance angiography with 2D cine MRI for characterizing anatomy and size. Journal Of Cardiovascular Magnetic Resonance 2005, 7: 355-60. PMID: 15881514, DOI: 10.1081/jcmr-200053458.Peer-Reviewed Original ResearchConceptsPulmonary vein ostial diametersMagnetic resonance angiographyPulmonary veinsCine CMROstial diameterNormal volunteersResonance angiographyAtrial fibrillation ablation proceduresAtrial fibrillation patientsPulmonary vein diameterCardiac magnetic resonanceCine cardiac magnetic resonanceThree-dimensional magnetic resonance angiographyContrast-enhanced 3D MRAFibrillation patientsAtrial fibrillationVein diameterAblation proceduresAnatomical depictionPatientsT scannerAngiographyCine MRICMRVein