2024
Digital Health Interventions for Hypertension Management in US Populations Experiencing Health Disparities
Katz M, Mszar R, Grimshaw A, Gunderson C, Onuma O, Lu Y, Spatz E. Digital Health Interventions for Hypertension Management in US Populations Experiencing Health Disparities. JAMA Network Open 2024, 7: e2356070. PMID: 38353950, PMCID: PMC10867699, DOI: 10.1001/jamanetworkopen.2023.56070.Peer-Reviewed Original ResearchConceptsDigital health interventionsHealth disparitiesHealth interventionsSystematic reviewSystolic BPSocial determinants of healthHypertension managementCommunity health workersFactors associated with cardiovascular diseaseDeterminants of healthLeveraging digital healthRemote BP monitoringDigital health technologiesStandard care groupMeta-analysisBlood pressureDiastolic BPPreferred Reporting ItemsControl groupSystolic BP changeBaseline to 6Random-effects modelSkilled nursingCultural tailoringSocial determinants
2023
Exercise Does Not Independently Improve Histological Outcomes in Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis
Chen G, Banini B, Do A, Gunderson C, Zaman S, Lim J. Exercise Does Not Independently Improve Histological Outcomes in Biopsy-Proven Non-Alcoholic Fatty Liver Disease: A Systematic Review and Meta-Analysis. Genes 2023, 14: 1811. PMID: 37761951, PMCID: PMC10531443, DOI: 10.3390/genes14091811.Peer-Reviewed Original ResearchConceptsNon-alcoholic fatty liver diseaseBiopsy-proven non-alcoholic fatty liver diseaseEffects of exerciseFatty liver diseaseHistological outcomesLiver histologyLiver diseaseClinical trialsHistological endpointsSystematic reviewSignificant histopathological improvementNAFLD activity scoreImpact of exerciseIndependent effectsRandom-effects modelSystematic literature searchHistopathological improvementExercise interventionActivity scoreClinical endpointsPooled estimatesMeta-AnalysisTotal participantsLiterature searchComparison groupBurden of bone disease in chronic pancreatitis: A systematic review and meta-analysis
Chhoda A, Hernandez-Woodbine M, Addo N, Nasir S, Grimshaw A, Gunderson C, Ahmed A, Freedman S, Sheth S. Burden of bone disease in chronic pancreatitis: A systematic review and meta-analysis. World Journal Of Gastroenterology 2023, 29: 1374-1394. PMID: 36925454, PMCID: PMC10011962, DOI: 10.3748/wjg.v29.i8.1374.Peer-Reviewed Original ResearchConceptsPrevalence of osteopeniaChronic pancreatitisFragility fracturesBone diseaseCP patientsClinical featuresPooled prevalenceSystematic reviewBaseline clinical featuresSignificant bone diseasePrevalence of osteoporosisBody mass indexCause of morbidityBone mineralization parametersRandom-effects modelPaucity of dataWeb of SciencePERT useSmoking exposureSystemic inflammationTherapy useMass indexTrue burdenCochrane LibraryMean age
2022
Benefit of Extended Surveillance of Low-Risk Pancreatic Cysts After 5-Year Stability: A Systematic Review and Meta-Analysis
Chhoda A, Singh S, Sheth AH, Grimshaw AA, Gunderson C, Sharma P, Kunstman JW, Sharma A, Ahuja N, Gonda TA, Farrell JJ. Benefit of Extended Surveillance of Low-Risk Pancreatic Cysts After 5-Year Stability: A Systematic Review and Meta-Analysis. Clinical Gastroenterology And Hepatology 2022, 21: 1430-1446. PMID: 35568304, DOI: 10.1016/j.cgh.2022.04.025.Peer-Reviewed Original ResearchConceptsDisease-specific mortalityAdvanced neoplasiaBD-IPMNsExtended surveillancePooled incidenceWorrisome featuresSystematic reviewIntraductal papillary mucinous neoplasmHigh-grade dysplasiaPapillary mucinous neoplasmHigh-quality studiesRandom-effects modelWarrants further investigationWeb of ScienceNeoplasia incidenceWarrants further explorationSurvival benefitCochrane LibraryMucinous neoplasmsPancreatic cancerPancreatic cystsSurveillance periodEligible studiesOvid MEDLINELower incidence
2021
Late-Stage Pancreatic Cancer Detected During High-Risk Individual Surveillance: A Systematic Review and Meta-Analysis
Chhoda A, Vodusek Z, Wattamwar K, Mukherjee E, Gunderson C, Grimshaw A, Sharma A, Ahuja N, Kastrinos F, Farrell JJ. Late-Stage Pancreatic Cancer Detected During High-Risk Individual Surveillance: A Systematic Review and Meta-Analysis. Gastroenterology 2021, 162: 786-798. PMID: 34813861, DOI: 10.1053/j.gastro.2021.11.021.Peer-Reviewed Original ResearchConceptsLate-stage PDACPancreatic ductal adenocarcinomaHigh-risk individualsHigh-grade precursorsCumulative incidenceAdvanced neoplasiaLate-stage pancreatic cancerTiming of presentationRandom-effects modelWeb of ScienceClinicoradiologic factorsClinicoradiologic featuresSurveillance imagingCochrane LibraryPancreatic cancerDuctal adenocarcinomaPancreatic morphologySurveillance studyFunnel plotLesion sitePDAC stagesSurveillance adherenceSystematic reviewMeta-AnalysisSignificant associationEvaluation of diagnostic yield of EUS among patients with asymptomatic common bile duct dilation: systematic review and meta-analysis
Chhoda A, Dawod S, Grimshaw A, Gunderson C, Mahadev S. Evaluation of diagnostic yield of EUS among patients with asymptomatic common bile duct dilation: systematic review and meta-analysis. Gastrointestinal Endoscopy 2021, 94: 890-901.e8. PMID: 34245751, DOI: 10.1016/j.gie.2021.07.002.Peer-Reviewed Original ResearchConceptsCommon bile duct dilationBile duct dilationAsymptomatic patientsBiliary dilationDiagnostic yieldCBD dilationDuct dilationEUS evaluationSystematic reviewHealth resource utilizationInverse variance methodRandom-effects modelCost-effectiveness analysisRadiologic evidenceBenign etiologyMalignant etiologyFrequent indicationOvid EmbaseAsymptomatic individualsCochrane LibraryMalignant pathologyOvid MEDLINEFurther interventionPatientsGoogle Scholar
2020
Rate of Preventable Mortality in Hospitalized Patients: a Systematic Review and Meta-analysis
Rodwin BA, Bilan VP, Merchant NB, Steffens CG, Grimshaw AA, Bastian LA, Gunderson CG. Rate of Preventable Mortality in Hospitalized Patients: a Systematic Review and Meta-analysis. Journal Of General Internal Medicine 2020, 35: 2099-2106. PMID: 31965525, PMCID: PMC7351940, DOI: 10.1007/s11606-019-05592-5.Peer-Reviewed Original ResearchConceptsInpatient deathPreventable mortalityPreventable deathsMortality rateHospital mortality rateLife expectancyRandom-effects modelSystematic literature searchNumber of deathsWeb of ScienceHospital deathAdult patientsHospitalized patientsResultsSixteen studiesCase seriesPooled rateCochrane LibraryInclusion criteriaPatientsMeta-AnalysisSystematic reviewLiterature searchData extractionMortalityDeath
2018
Do Patients with Cellulitis Need to be Hospitalized? A Systematic Review and Meta-analysis of Mortality Rates of Inpatients with Cellulitis
Gunderson CG, Cherry BM, Fisher A. Do Patients with Cellulitis Need to be Hospitalized? A Systematic Review and Meta-analysis of Mortality Rates of Inpatients with Cellulitis. Journal Of General Internal Medicine 2018, 33: 1553-1560. PMID: 30022408, PMCID: PMC6108983, DOI: 10.1007/s11606-018-4546-z.Peer-Reviewed Original ResearchConceptsInfectious Diseases SocietyOutpatient managementMortality rateDiseases SocietyNewcastle-Ottawa Quality Assessment ScaleActual clinical evidencePneumonia severity indexCommunity-acquired pneumoniaLow-risk patientsQuality Assessment ScaleThird of deathsWorldwide mortality rateRandom-effects modelSystematic literature searchInpatient mortalityRisk patientsConsecutive patientsClinical evidenceResultsEighteen studiesDiseases codesI2 statisticCommon causeInclusion criteriaStudy qualityCellulitis
2013
Risk of deep vein thrombosis in patients with cellulitis and erysipelas A systematic review and meta-analysis
Gunderson CG, Chang JJ. Risk of deep vein thrombosis in patients with cellulitis and erysipelas A systematic review and meta-analysis. Thrombosis Research 2013, 132: 336-340. PMID: 23948644, DOI: 10.1016/j.thromres.2013.07.021.Peer-Reviewed Original ResearchConceptsDeep vein thrombosisPrevalence of DVTPooled incidence rateCompression ultrasoundIncidence rateDVT rateVein thrombosisNewcastle-Ottawa Quality Assessment ScaleRisk of DVTOverall pooled incidence rateProximal deep vein thrombosisOverall DVT rateUnilateral limb swellingLow-risk patientsGroup of patientsQuality Assessment ScaleRandom-effects modelSystematic literature searchCohort studyRisk patientsCommon presentationLimb swellingProspective studyRetrospective studyCellulitis