2019
Advancing Precision Medicine for Alcohol Use Disorder: Replication and Extension of Reward Drinking as a Predictor of Naltrexone Response
Witkiewitz K, Roos CR, Mann K, Kranzler HR. Advancing Precision Medicine for Alcohol Use Disorder: Replication and Extension of Reward Drinking as a Predictor of Naltrexone Response. Alcohol Clinical And Experimental Research 2019, 43: 2395-2405. PMID: 31436886, PMCID: PMC6824945, DOI: 10.1111/acer.14183.Peer-Reviewed Original ResearchMeSH KeywordsAlcohol DeterrentsAlcohol DrinkingAlcoholismFemaleHumansMaleMiddle AgedNaltrexonePrecision MedicineRewardTreatment OutcomeConceptsEffects of naltrexoneHeavy drinking daysAlcohol use disorderDaily naltrexoneUse disordersDrinking daysDaily drinkingPercent heavy drinking daysPrecision medicinePrecision medicine approachDaily medicationNaltrexone responseInteractive voice response technologyClinical trialsNaltrexone effectsRewarding effectsSpecific treatmentNaltrexoneSecondary analysisMedicine approachDrinkersProblem drinkersReward drinkersPlaceboDrinking
2018
Response to Letter to Editor (Precision medicine in alcohol dependence: evidence of efficacy and initial support for comparative effectiveness)
Mann K, Roos CR, Witkiewitz K. Response to Letter to Editor (Precision medicine in alcohol dependence: evidence of efficacy and initial support for comparative effectiveness). Neuropsychopharmacology 2018, 43: 1801-1802. PMID: 29930387, PMCID: PMC6046056, DOI: 10.1038/s41386-018-0113-x.Peer-Reviewed Original Research
2017
Mindfulness-Based Interventions for Addictive Behaviors: Implementation Issues on the Road Ahead
Wilson AD, Roos CR, Robinson CS, Stein ER, Manuel JA, Enkema MC, Bowen S, Witkiewitz K. Mindfulness-Based Interventions for Addictive Behaviors: Implementation Issues on the Road Ahead. Psychology Of Addictive Behaviors 2017, 31: 888-896. PMID: 29072477, PMCID: PMC5714676, DOI: 10.1037/adb0000319.Peer-Reviewed Original ResearchPrecision Medicine in Alcohol Dependence: A Controlled Trial Testing Pharmacotherapy Response Among Reward and Relief Drinking Phenotypes
Mann K, Roos CR, Hoffmann S, Nakovics H, Leménager T, Heinz A, Witkiewitz K. Precision Medicine in Alcohol Dependence: A Controlled Trial Testing Pharmacotherapy Response Among Reward and Relief Drinking Phenotypes. Neuropsychopharmacology 2017, 43: 891-899. PMID: 29154368, PMCID: PMC5809801, DOI: 10.1038/npp.2017.282.Peer-Reviewed Original ResearchConceptsBetter treatment responseAlcohol dependenceTreatment responsePREDICT studyAnalysis of subgroupsSubgroup of individualsRelief scoresActive medicationRandomized trialsAD patientsSelf-report questionnairesMedicationsNaltrexonePharmacotherapy responseHigher effect sizesHeavy drinkingClinical applicabilityCutoff analysisDrinking phenotypesPlaceboPrecision medicineDrinkersPatientsEffect sizeDrinking