2018
Abstinence and Low Risk Drinking During Treatment: Association With Psychosocial Functioning, Alcohol Use, and Alcohol Problems 3 Years Following Treatment
Witkiewitz K, Kirouac M, Roos CR, Wilson AD, Hallgren KA, Bravo AJ, Montes KS, Maisto SA. Abstinence and Low Risk Drinking During Treatment: Association With Psychosocial Functioning, Alcohol Use, and Alcohol Problems 3 Years Following Treatment. Psychology Of Addictive Behaviors 2018, 32: 639-646. PMID: 30160499, PMCID: PMC6136973, DOI: 10.1037/adb0000381.Peer-Reviewed Original ResearchConceptsLow-risk drinkingRisk drinkingHeavy drinkingDrinking daysAlcohol-related consequencesAlcohol usePersistent heavy drinkingWeeks of treatmentOutcomes 3 yearsDrinking outcomesHeavy drinking daysLow-risk drinkersAlcohol use disorderMeasures latent class analysisOutpatient armRisk drinkersOutcome measuresHeavy drinking episodesLower riskUse disordersHeavy drinkersFunctioning outcomesPsychosocial functioningAbstinenceDrinking episodesBroad Coping Repertoire Mediates the Effect of the Combined Behavioral Intervention on Alcohol Outcomes in the COMBINE Study: An Application of Latent Class Mediation.
Witkiewitz K, Roos CR, Tofighi D, Van Horn ML. Broad Coping Repertoire Mediates the Effect of the Combined Behavioral Intervention on Alcohol Outcomes in the COMBINE Study: An Application of Latent Class Mediation. Journal Of Studies On Alcohol And Drugs 2018, 79: 199-207. PMID: 29553346, PMCID: PMC6019776, DOI: 10.15288/jsad.2018.79.199.Peer-Reviewed Original ResearchConceptsAlcohol use disorderMedication managementBehavioral interventionsDrinking outcomesOutcomes 12 monthsCombined Behavioral InterventionCombined PharmacotherapiesUse disordersAUD treatmentCoping repertoireCOMBINE StudySecondary analysisSignificant mediatorAlcohol Dependence (COMBINE) StudyBehavioral treatmentIntervention efficacyBroad coping repertoireMultisite studyInterventionGreater likelihoodOutcomesTreatmentMediatorsAlcohol outcomesBehavior change
2017
Coping mediates the effects of cognitive–behavioral therapy for alcohol use disorder among out‐patient clients in Project MATCH when dependence severity is high
Roos CR, Maisto SA, Witkiewitz K. Coping mediates the effects of cognitive–behavioral therapy for alcohol use disorder among out‐patient clients in Project MATCH when dependence severity is high. Addiction 2017, 112: 1547-1557. PMID: 28388836, PMCID: PMC5544539, DOI: 10.1111/add.13841.Peer-Reviewed Original ResearchConceptsAlcohol use disorderTwelve-step facilitationCognitive behavioral therapyMotivational enhancement therapyUse disordersPositive treatment effectDependence severityDrinking outcomesTreatment effectsProject MATCHPercentage days abstinentHeavy drinking daysAlcohol Treatment TrialPrimary outcomeTreatment armsTreatment trialsSecondary data analysisDays abstinentDrinking daysAlcohol Dependence ScaleTherapyPatient samplesEnhancement therapySeverityChange Questionnaire
2016
Reward and relief dimensions of temptation to drink: construct validity and role in predicting differential benefit from acamprosate and naltrexone
Roos CR, Mann K, Witkiewitz K. Reward and relief dimensions of temptation to drink: construct validity and role in predicting differential benefit from acamprosate and naltrexone. Addiction Biology 2016, 22: 1528-1539. PMID: 27480445, PMCID: PMC5290305, DOI: 10.1111/adb.12427.Peer-Reviewed Original ResearchConceptsAlcohol use disorderTreatment of AUDOpioid receptor antagonistRandomized clinical trialsBetter drinking outcomesGlutamatergic systemSubtypes of individualsReceptor antagonistClinical trialsRewarding effectsUse disordersClinical decisionDrinking outcomesReward drinkersDrinkersNaltrexoneExcellent reliabilityDifferential benefitsDistinct patterns
2015
Examining Temptation to Drink From an Existential Perspective: Associations Among Temptation, Purpose in Life, and Drinking Outcomes
Roos CR, Kirouac M, Pearson MR, Fink BC, Witkiewitz K. Examining Temptation to Drink From an Existential Perspective: Associations Among Temptation, Purpose in Life, and Drinking Outcomes. Psychology Of Addictive Behaviors 2015, 29: 716-724. PMID: 25730630, PMCID: PMC4558413, DOI: 10.1037/adb0000063.Peer-Reviewed Original ResearchConceptsAlcohol use disorderDrinking outcomesCourse of treatmentHigher initial levelsInitial levelAlcohol treatment outcomesFrequency of drinkingKind of treatmentLower initial levelsAlcohol-related cuesCurve analysisLongitudinal associationsDrinking-related consequencesExistential issuesProject MATCHOutcomesTreatmentLatent growth curve analysisFuture studiesGrowth curve analysisTTDDrinkingCurrent studyAssociationLevelsThe Indirect Effect of the Therapeutic Alliance and Alcohol Abstinence Self‐Efficacy on Alcohol Use and Alcohol‐Related Problems in Project MATCH
Maisto SA, Roos CR, O'Sickey AJ, Kirouac M, Connors GJ, Tonigan JS, Witkiewitz K. The Indirect Effect of the Therapeutic Alliance and Alcohol Abstinence Self‐Efficacy on Alcohol Use and Alcohol‐Related Problems in Project MATCH. Alcohol Clinical And Experimental Research 2015, 39: 504-513. PMID: 25704134, PMCID: PMC4457319, DOI: 10.1111/acer.12649.Peer-Reviewed Original ResearchConceptsAlcohol use disorderTherapeutic allianceCognitive behavioral treatment groupClient ratingsBehavioral treatment groupEffects of therapistSelf-efficacy changeProject MATCH dataAlcohol-related outcomesAUD treatment outcomesTwelve-step facilitationAlcohol abstinencePosttreatment drinking outcomesMotivation enhancementWorking Alliance InventoryModeration effectMediation analysisDrinking outcomesTherapist ratingsStatistical mediatorAUD outcomesAlliance ratingsAlcohol useAlliance InventoryIndirect effects