An integrative approach to ortholog prediction for disease-focused and other functional studies
Hu Y, Flockhart I, Vinayagam A, Bergwitz C, Berger B, Perrimon N, Mohr SE. An integrative approach to ortholog prediction for disease-focused and other functional studies. BMC Bioinformatics 2011, 12: 357. PMID: 21880147, PMCID: PMC3179972, DOI: 10.1186/1471-2105-12-357.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsDatabases, GeneticDiseaseDisease Models, AnimalEvolution, MolecularGenetic Predisposition to DiseaseGenome-Wide Association StudyHumansConceptsGenome-wide association studiesIdentification of orthologsModel organismsDisease genesFunctions of human disease genesHuman disease-associated genesGenome-wide association study data setsOrthologous gene relationshipsFunction of orthologsHuman disease genesPercent amino acid identityAmino acid identityDisease-associated genesOnline Mendelian InheritancePossible orthologsOrthologous genesOrtholog predictionOrtholog pairsFunctional genomicsGene functionC. elegansOrthology predictionOrthologous pairsGene relationshipsS. cerevisiae