Chapter 7 Phosphate Homeostasis Regulatory Mechanisms
Bergwitz C, Jüppner H. Chapter 7 Phosphate Homeostasis Regulatory Mechanisms. 2012, 141-161. DOI: 10.1016/b978-0-12-382040-2.10007-3.ChaptersRegulatory mechanismsBone-forming osteoblastsPi homeostasisMonocyte-macrophage lineage cellsBone-resorbing cellsPi concentrationMacrophage colony-stimulating factorSkeletal developmentFunction of chondrocytesExtracellular matrixLineage cellsMatrix productionOsteogenic cellsMajor functionColony-stimulating factorBone-resorbing osteoclastsPlasma Pi concentrationCellsOsteoblastsIntegral componentFunction of boneRate of bone growthAmbient Pi concentrationsMechanical supportHydroxyapatite crystals