2020
Transition to Advanced Therapies in Elderly Patients Supported by Extracorporeal Membrane Oxygenation Therapy
Chouairi F, Vallabhajosyula S, Mullan C, Mori M, Geirsson A, Desai NR, Ahmad T, Miller PE. Transition to Advanced Therapies in Elderly Patients Supported by Extracorporeal Membrane Oxygenation Therapy. Journal Of Cardiac Failure 2020, 26: 1086-1089. PMID: 32777479, DOI: 10.1016/j.cardfail.2020.07.019.Peer-Reviewed Original ResearchConceptsExtracorporeal membrane oxygenationOrthotopic cardiac transplantationCardiogenic shockAdvanced therapiesVentricular assist device implantationNational Inpatient Sample databaseExtracorporeal membrane oxygenation therapyYounger groupStudy periodAssist device implantationMembrane oxygenation therapyProportion of patientsSurvival of patientsHospitalizations of peopleOlder age groupsHospital mortalityCardiac transplantationECMO supportMultivariable adjustmentElderly patientsLVAD implantationMembrane oxygenationOxygenation therapyPrimary outcomeDevice implantationPsychiatric Comorbidity and Outcomes After Left Ventricular Assist Device Implantation for End-Stage Heart Failure
Mullan C, Caraballo C, Ravindra NG, Miller PE, McCullough M, Brown K, Aw TW, Gruen J, Clarke JD, Velazquez EJ, Geirsson A, Mori M, Desai NR, Ahmad T. Psychiatric Comorbidity and Outcomes After Left Ventricular Assist Device Implantation for End-Stage Heart Failure. JACC Heart Failure 2020, 8: 569-577. PMID: 32535119, DOI: 10.1016/j.jchf.2020.03.011.Peer-Reviewed Original ResearchConceptsPsychiatric comorbidityMajor psychiatric illnessNarcotic dependencePsychiatric illnessAdverse eventsHeart failureAlcohol abuseKansas City Cardiomyopathy Questionnaire scoreDrug useVentricular assist device implantationEnd-stage heart failureMechanically Assisted Circulatory SupportAssist device implantationEnd-stage heartRisk of rehospitalizationContinuous-flow LVADRisk of mortalityVulnerable patient populationVentricular assist deviceDevice-related infectionsInteragency RegistryLVAD recipientsSpecific psychiatric conditionsClinical outcomesPatient selectionClinical impact of concomitant tricuspid valve procedures during left ventricular assist device implantation
Mullan C, Caraballo C, Ravindra NG, Miller PE, Mori M, McCullough M, Clarke JD, Anwer M, Velazquez EJ, Geirsson A, Desai NR, Ahmad T. Clinical impact of concomitant tricuspid valve procedures during left ventricular assist device implantation. The Journal Of Heart And Lung Transplantation 2020, 39: 926-933. PMID: 32593561, DOI: 10.1016/j.healun.2020.05.007.Peer-Reviewed Original ResearchConceptsConcomitant tricuspid valve proceduresTricuspid valve proceduresSevere tricuspid regurgitationTricuspid regurgitationLVAD implantationValve proceduresLeft ventricular assist device implantationVentricular assist device implantationDegree of TREnd-stage heart failureAssist device implantationRisk of bleedingCases of mildContinuous-flow LVADVentricular assist deviceInteragency RegistryAdult patientsAdverse eventsSurvival benefitHeart failureClinical outcomesDevice implantationTR severityQOL outcomesClinical impact
2019
Clinical Outcomes After Left Ventricular Assist Device Implantation in Older Adults An INTERMACS Analysis
Caraballo C, DeFilippis EM, Nakagawa S, Ravindra NG, Miller PE, Mezzacappa C, McCullough M, Gruen J, Levin A, Reinhardt S, Mullan C, Ali A, Maurer MS, Desai NR, Ahmad T, Topkara VK. Clinical Outcomes After Left Ventricular Assist Device Implantation in Older Adults An INTERMACS Analysis. JACC Heart Failure 2019, 7: 1069-1078. PMID: 31779930, DOI: 10.1016/j.jchf.2019.10.004.Peer-Reviewed Original ResearchConceptsYears of ageVentricular assist device implantationAssist device implantationOlder adultsElderly patientsLVAD implantationDevice implantationMultivariate Cox proportional hazards regression modelCox proportional hazards regression modelKaplan-Meier survival estimatesMechanically Assisted Circulatory SupportProportional hazards regression modelsMechanical circulatory support technologyPost-LVAD outcomesHeart failure populationLog-rank testingSerum albumin levelPredictors of survivalPost-LVAD implantationHazards regression modelsPredictors of outcomeAge-specific outcomesAntithrombotic regimenDurable MCSINTERMACS Analysis