2018
Epidemiology of Lower Extremity Deep Venous Thrombosis in Critically Ill Adolescents
Faustino EVS, Shabanova V, Pinto MG, Li S, Trakas E, Miksa M, Gertz S, Polikoff LA, Napolitano M, Brudnicki AR, Tala JA, Silva CT, Investigators T, Miksa M, Taragin B, Blickman J, Taillie E, Trakas E, Balasco A, Herliczek T, Polikoff L, Dovi G, Napolitano M, Gertz S, Riordan M, Zasa J, Brudnicki A, Eldridge P, Li S, Pinto M, Faustino E, Silva C, Tala J. Epidemiology of Lower Extremity Deep Venous Thrombosis in Critically Ill Adolescents. The Journal Of Pediatrics 2018, 201: 176-183.e2. PMID: 29891258, DOI: 10.1016/j.jpeds.2018.05.006.Peer-Reviewed Original ResearchConceptsDeep venous thrombosisExtremity deep venous thrombosisIll adolescentsVenous thrombosisFrequency of DVTLower extremity deep venous thrombosisCases of DVTBilateral deep venous thrombosisPediatric intensive care unitInvasive mechanical ventilationCentral venous catheterizationIntensive care unitPharmacologic prophylaxisTherapeutic anticoagulationCohort studyPulmonary embolismCardiopulmonary supportCare unitMechanical ventilationVenous catheterizationSevere illnessSerial sonogramsLower extremitiesEpidemiologyThrombosis
2015
Diagnostic accuracy of point-of-care ultrasound for catheter-related thrombosis in children
Li S, Silva CT, Brudnicki AR, Baker KE, Tala JA, Pinto MG, Polikoff LA, Qin L, Faustino EV, Northeast Pediatric Critical Care Research Consortium. Diagnostic accuracy of point-of-care ultrasound for catheter-related thrombosis in children. Pediatric Radiology 2015, 46: 219-228. PMID: 26440129, PMCID: PMC4738063, DOI: 10.1007/s00247-015-3467-9.Peer-Reviewed Original ResearchMeSH KeywordsAge DistributionCausalityCentral Venous CathetersChildChild, PreschoolCohort StudiesConnecticutFemaleHumansInfantInfant, NewbornMalePoint-of-Care TestingPrevalenceReproducibility of ResultsRisk FactorsSensitivity and SpecificitySex DistributionUltrasonographyUpper Extremity Deep Vein ThrombosisConceptsCatheter-related thrombosisCare ultrasoundChance-corrected agreementIll childrenCare USCentral venous catheter-related thrombosisPediatric radiologistsDeep venous thrombosisCentral venous cathetersIntensive care unitVenous cathetersVenous thrombosisCare unitSubclavian veinThrombosisAccuracy of pointCatheterSensitivity of pointDiscordant readingsDiagnostic accuracyMulticenterUltrasoundRadiology departmentChildrenPhysiciansFactor VIII May Predict Catheter-Related Thrombosis in Critically Ill Children
Faustino EV, Li S, Silva CT, Pinto MG, Qin L, Tala JA, Rinder HM, Kupfer GM, Shapiro ED. Factor VIII May Predict Catheter-Related Thrombosis in Critically Ill Children. Pediatric Critical Care Medicine 2015, 16: 497-504. PMID: 25828784, PMCID: PMC4497863, DOI: 10.1097/pcc.0000000000000409.Peer-Reviewed Original ResearchConceptsCatheter-related thrombosisFactor VIII activityIncident thrombosisIll childrenVIII activityCentral venous catheter-related thrombosisDays of enrollmentProspective cohort studyCentral venous cathetersImportant clinical predictorsTertiary academic centerIU/dlPharmacologic thromboprophylaxisSurveillance ultrasonographyCohort studyVenous cathetersClinical predictorsThrombotic eventsOdds ratioSD increaseHigh riskThrombosisAcademic centersFactor VIIIYouden indexPrevalence of post‐thrombotic syndrome after cardiac catheterization
Luceri MJ, Tala JA, Weismann CG, Silva CT, Faustino EV. Prevalence of post‐thrombotic syndrome after cardiac catheterization. Pediatric Blood & Cancer 2015, 62: 1222-1227. PMID: 25663038, PMCID: PMC4433560, DOI: 10.1002/pbc.25438.Peer-Reviewed Original ResearchConceptsPost-thrombotic syndromeCardiac catheterizationFirst catheterizationCyanotic congenital heart diseaseManco-Johnson instrumentDeep venous thrombosisSurvival of childrenTime of enrollmentCongenital heart diseaseCross-sectional studyChronic complicationsCommon complicationMedian ageVenous thrombosisValvular insufficiencyFemoral veinHeart diseaseSignificant syndromeAntithrombotic agentsCatheterizationSyndromeDisease increasesThrombosisComplicationsChildren
2012
Incidence and Acute Complications of Asymptomatic Central Venous Catheter–Related Deep Venous Thrombosis in Critically Ill Children
Faustino EV, Spinella PC, Li S, Pinto MG, Stoltz P, Tala J, Card ME, Northrup V, Baker KE, Goodman TR, Chen L, Silva CT. Incidence and Acute Complications of Asymptomatic Central Venous Catheter–Related Deep Venous Thrombosis in Critically Ill Children. The Journal Of Pediatrics 2012, 162: 387-391. PMID: 22883418, PMCID: PMC3575007, DOI: 10.1016/j.jpeds.2012.06.059.Peer-Reviewed Original ResearchConceptsCVC-related deep venous thrombosisDeep venous thrombosisCentral venous cathetersIntensive care unitAcute complicationsIll childrenVenous cathetersVenous thrombosisCare unitPediatric intensive care unitProspective cohort studyChronic complicationsHospital lengthCohort studyPatient demographicsPulmonary embolismCompression ultrasonographyMechanical ventilationHigher oddsCurrent incidenceColor DopplerComplicationsCVC characteristicsLarger studyThrombosis