2021
A neutrophil activation signature predicts critical illness and mortality in COVID-19
Meizlish ML, Pine AB, Bishai JD, Goshua G, Nadelmann ER, Simonov M, Chang CH, Zhang H, Shallow M, Bahel P, Owusu K, Yamamoto Y, Arora T, Atri DS, Patel A, Gbyli R, Kwan J, Won CH, Dela Cruz C, Price C, Koff J, King BA, Rinder HM, Wilson FP, Hwa J, Halene S, Damsky W, van Dijk D, Lee AI, Chun HJ. A neutrophil activation signature predicts critical illness and mortality in COVID-19. Blood Advances 2021, 5: 1164-1177. PMID: 33635335, PMCID: PMC7908851, DOI: 10.1182/bloodadvances.2020003568.Peer-Reviewed Original ResearchConceptsCritical illnessHealth system databaseNeutrophil activationCOVID-19Neutrophil activation signatureSevere COVID-19Intensive care unitGranulocyte colony-stimulating factorHigh mortality rateColony-stimulating factorSystem databaseHepatocyte growth factorClinical decompensationNeutrophil countImmune hyperactivationCare unitEarly elevationLipocalin-2Interleukin-8Longitudinal cohortClinical dataMortality ratePatientsIllnessActivation signature
2017
Impact of Sleep Breathing Disorders in Obese Critically Ill Patients
Al-Halawani M, Won C. Impact of Sleep Breathing Disorders in Obese Critically Ill Patients. 2017, 77-85. DOI: 10.1007/978-3-319-49253-7_8.Peer-Reviewed Original ResearchSleep breathing disordersBreathing disordersObesity hypoventilation syndromeObstructive sleep apneaSleep-disordered breathingIntensive care unitObese patientsHypoventilation syndromeIll patientsCare unitSleep apneaIll populationMajor causeObesePatientsDisordersRiskSerious riskApneaICUMorbidityComplicationsSyndromeMortalityBreathing