2023
Retinal Ischemic Perivascular Lesions in Individuals With Atrial Fibrillation
Bakhoum C, Madala S, Lando L, Yarmohammadi A, Long C, Miguez S, Chan A, Singer M, Jin A, Steren B, Adabifirouzjaei F, Goldbaum M, DeMaria A, Sarraf D, Bakhoum M. Retinal Ischemic Perivascular Lesions in Individuals With Atrial Fibrillation. Journal Of The American Heart Association 2023, 12: e028853. PMID: 37577936, PMCID: PMC10492933, DOI: 10.1161/jaha.122.028853.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAtrial FibrillationCase-Control StudiesHumansIschemiaMiddle AgedRisk FactorsStrokeConceptsOptical coherence tomography scansAtrial fibrillationPerivascular lesionsTomography scanSpectral domain optical coherence tomography scansMacular spectral-domain optical coherence tomographySpectral-domain optical coherence tomographyMultivariable logistic regression modelCardiovascular risk factorsDomain optical coherence tomographyAtrial fibrillation groupCoronary artery diseaseIschemic heart diseaseSex-matched individualsCase-control studyPercentage of subjectsIschemic cardiovascular diseaseOptical coherence tomographyLogistic regression modelsCardiovascular workupCardiac emboliFibrillation groupSmoking historyArtery diseaseCarotid stenosis
2022
Retinal vein occlusion is associated with stroke independent of underlying cardiovascular disease
Bakhoum C, Madala S, Long C, Adabifirouzjaei F, Freeman W, Goldbaum M, DeMaria A, Bakhoum M. Retinal vein occlusion is associated with stroke independent of underlying cardiovascular disease. Eye 2022, 37: 764-767. PMID: 35411111, PMCID: PMC9998396, DOI: 10.1038/s41433-022-02038-x.Peer-Reviewed Original ResearchMeSH KeywordsAgedCardiovascular DiseasesCross-Sectional StudiesHumansHypertensionRetinal Vein OcclusionRisk FactorsStrokeConceptsRetinal vein occlusionPresence of RVORisk of strokeCardiovascular diseaseOdds ratioVein occlusionRisk factorsMultivariable logistic regression modelCoronary artery diseaseCross-sectional studyYears of ageLogistic regression modelsArtery diseaseDiabetes mellitusCarotid diseaseStroke developmentAtrial fibrillationLeading causeYoung subjectsEarly interventionStrokeOlder individualsConclusionsOur findingsDiseaseRiskNocturnal Dipping and Left Ventricular Mass Index in the Chronic Kidney Disease in Children Cohort
Bakhoum C, Katz R, Samuels J, Al-Rousan T, Furth S, Ix J, Garimella P. Nocturnal Dipping and Left Ventricular Mass Index in the Chronic Kidney Disease in Children Cohort. Clinical Journal Of The American Society Of Nephrology 2022, 17: 75-82. PMID: 34772729, PMCID: PMC8763165, DOI: 10.2215/cjn.09810721.Peer-Reviewed Original ResearchConceptsLeft ventricular mass indexHigher left ventricular mass indexVentricular mass indexChronic kidney diseaseMass indexDiastolic dippingGreater proteinuriaSodium intakeKidney diseaseFemale sexRisk factorsAmbulatory BP monitoringHigh sodium intakeNocturnal BP declineCross-sectional analysisSpline regression analysisNonglomerular CKDSystolic dippingNocturnal dippingBP declineBP monitoringMean ageBlack raceEchocardiographic dataChild Cohort
2021
Relationship between Retinal Vascular Occlusions and Cognitive Dementia in a Large Cross-Sectional Cohort
Chan AX, Bakhoum CY, Bangen KJ, Bakhoum MF. Relationship between Retinal Vascular Occlusions and Cognitive Dementia in a Large Cross-Sectional Cohort. American Journal Of Ophthalmology 2021, 226: 201-205. PMID: 33529587, PMCID: PMC9227960, DOI: 10.1016/j.ajo.2021.01.026.Peer-Reviewed Original ResearchConceptsRetinal vascular occlusionVascular occlusionCognitive dementiaHigh prevalenceMultiple logistic regression analysisCross-sectional studyLogistic regression analysisYears of ageElectronic medical recordsMedical visitsMedical recordsRisk factorsDiagnostic codesStudy populationInternational ClassificationSectional cohortSignificant associationDementiaOlder ageOcclusionStrokeAgeRegression analysisPrevalenceAssociationProteinuria and nocturnal blood pressure dipping in hypertensive children and adolescents
Bakhoum CY, Vuong KT, Carter CE, Gabbai FB, Ix JH, Garimella PS. Proteinuria and nocturnal blood pressure dipping in hypertensive children and adolescents. Pediatric Research 2021, 90: 876-881. PMID: 33504962, PMCID: PMC8313642, DOI: 10.1038/s41390-020-01315-3.Peer-Reviewed Original ResearchConceptsAmbulatory blood pressure monitoringBody mass indexAssociation of proteinuriaBlood pressureRisk factorsUrine PCRNocturnal blood pressure dippingKidney function declineNocturnal blood pressureAdverse cardiovascular outcomesElevated blood pressureModifiable risk factorsDiastolic blood pressureGlomerular filtration rateBlood pressure dippingBlood pressure monitoringSpot urine proteinHypertensive childrenImpactOur studyCardiovascular outcomesCreatinine ratioFunction declineMass indexProspective studyUrine protein