2020
Muscarinic Regulation of Spike Timing Dependent Synaptic Plasticity in the Hippocampus
Fuenzalida M, Chiu C, Chávez A. Muscarinic Regulation of Spike Timing Dependent Synaptic Plasticity in the Hippocampus. Neuroscience 2020, 456: 50-59. PMID: 32828940, DOI: 10.1016/j.neuroscience.2020.08.015.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsCholinergic AgentsHippocampusNeuronal PlasticitySynapsesSynaptic TransmissionConceptsSpike timing dependent synaptic plasticityTiming-dependent plasticityCellular basis of learningMagnitude of long-term changesMuscarinic receptorsInhibitory synapsesMuscarinic regulationSynaptic transmissionSynaptic plasticityShape learningCentral synapsesBasis of learningCellular basisNetwork activityBrain network activityLong-term changesAcetylcholineHippocampusLearningSynapsesSTDPBrainMuscarinicMemoryReceptors
2019
Preserving the balance: diverse forms of long-term GABAergic synaptic plasticity
Chiu CQ, Barberis A, Higley MJ. Preserving the balance: diverse forms of long-term GABAergic synaptic plasticity. Nature Reviews Neuroscience 2019, 20: 272-281. PMID: 30837689, DOI: 10.1038/s41583-019-0141-5.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAnimalsBrainGABAergic NeuronsNeural InhibitionNeuronal PlasticitySynapsesConceptsGABAergic synaptic plasticityInhibitory GABAergic synapsesPostsynaptic action potentialsInhibitory synaptic strengthGABAergic synapsesSynaptic excitationLong-term plasticityGlutamatergic signalingNeuronal activitySynaptic plasticityNeuronal circuitsAction potentialsSynaptic strengthIndividual neuronsCellular mechanismsLines of evidenceBody of literaturePlasticityNeuronsFunctional stabilitySynapses
2004
Small modulation of ongoing cortical dynamics by sensory input during natural vision
Fiser J, Chiu C, Weliky M. Small modulation of ongoing cortical dynamics by sensory input during natural vision. Nature 2004, 431: 573-578. PMID: 15457262, DOI: 10.1038/nature02907.Peer-Reviewed Original ResearchMeSH KeywordsAction PotentialsAgingAnimalsEvoked Potentials, VisualFerretsNeuronsPhotic StimulationSaccadesVisual CortexVisual PerceptionConceptsDynamics of spontaneous activitySpontaneous activityVisual cortexPrimary visual cortexRandom spontaneous activitySpontaneous neural firingVisual cortical neuronsMature visual cortexCortical dynamicsNeural activityEvoked neural activitySensory inputInput signalCortical neuronsCircuit dynamicsNeural firingVisual stimulationMature animalsDynamicsYoung animalsFilm imagesCortexNeural responsesNatural visionNatural viewing conditions
2002
Relationship of Correlated Spontaneous Activity to Functional Ocular Dominance Columns in the Developing Visual Cortex
Chiu C, Weliky M. Relationship of Correlated Spontaneous Activity to Functional Ocular Dominance Columns in the Developing Visual Cortex. Neuron 2002, 35: 1123-1134. PMID: 12354401, DOI: 10.1016/s0896-6273(02)00867-x.Peer-Reviewed Original ResearchConceptsOcular dominance columnsVisual cortexDominance columnsPatterns of correlated activitySpontaneous activityOrganization of ocular dominance columnsRegions of visual cortexCorrelated spontaneous activityLGN afferentsOcular dominance patchesPeriodic alternationCortical connectivityPostnatal developmentIntrinsic periodCortical neuronsOcular dominanceFluctuationsMultielectrode arraysCorrelated activityCortexPeriodic fluctuationsBand
2001
Spontaneous Activity in Developing Ferret Visual Cortex In Vivo
Chiu C, Weliky M. Spontaneous Activity in Developing Ferret Visual Cortex In Vivo. Journal Of Neuroscience 2001, 21: 8906-8914. PMID: 11698602, PMCID: PMC6762264, DOI: 10.1523/jneurosci.21-22-08906.2001.Peer-Reviewed Original ResearchConceptsLateral geniculate nucleusVisual cortex in vivoVisual cortexSpontaneous activityPatterns of correlated activityTiming of spiking activityPatterns of spontaneous activityCortex in vivoExtracellular neuronal activityGeniculate nucleusLong-rangePostnatal dayExtracellular recordingsSpike activityNeuronal activityCross-correlation analysisIntrinsic circuitsSynchronous burstsCortical sitesCortexRecording sitesEye openingCorrelated activityAnatomical organizationPatchy organization