Subcortical structures associated with childhood trauma and perceived stress in schizophrenia
Fan F, Tan S, Liu S, Chen S, Huang J, Wang Z, Yang F, Li CR, Tan Y. Subcortical structures associated with childhood trauma and perceived stress in schizophrenia. Psychological Medicine 2022, 53: 5654-5662. PMID: 36154670, DOI: 10.1017/s0033291722002860.Peer-Reviewed Original ResearchConceptsGray matter volumeAmygdala gray matter volumeSubcortical gray matter volumesClinical symptomsEarly life traumaChildhood traumaSubcortical structuresCortical gray matter volumePerceived stressTotal cortical gray matter volumeAge-matched controlsSmaller amygdala volumesStructural brain imagingClinical featuresClinical manifestationsTrauma ScoreHealthy controlsChildhood trauma scoresLong-term effectsAmygdala volumePatientsMatter volumeEarly childhood traumaSmaller amygdalaVolumetric correlates