2024
Deficient sleep, altered hypothalamic functional connectivity, depression and anxiety in cigarette smokers
Chen Y, Chaudhary S, Li G, Fucito L, Bi J, Li C. Deficient sleep, altered hypothalamic functional connectivity, depression and anxiety in cigarette smokers. Neuroimage Reports 2024, 4: 100200. PMID: 38605733, PMCID: PMC11008573, DOI: 10.1016/j.ynirp.2024.100200.Peer-Reviewed Original ResearchResting state functional connectivitySeverity of depressionPittsburgh Sleep Quality IndexMotivated behaviorNicotine dependenceFunctional connectivityPittsburgh Sleep Quality Index scoreAchenbach Adult Self-ReportSeverity of alcohol useAssociated with greater severityComorbid nicotine dependenceDeficient sleepAdult Self-ReportHypothalamic functional connectivityHuman Connectome ProjectAnxiety disordersAnxiety severityPublished routinesAnxiety symptomsCircuit dysfunctionGreater severityPsychiatric problemsSleep-wake cyclePoor sleep qualityNeural markers
2019
Threat bias and resting state functional connectivity of the amygdala and bed nucleus stria terminalis
Jenks SK, Zhang S, Li CR, Hu S. Threat bias and resting state functional connectivity of the amygdala and bed nucleus stria terminalis. Journal Of Psychiatric Research 2019, 122: 54-63. PMID: 31927266, PMCID: PMC7010552, DOI: 10.1016/j.jpsychires.2019.12.017.Peer-Reviewed Original ResearchConceptsHealthy controlsState functional connectivityStria terminalisFunctional connectivityAnxiety disordersBed nucleus stria terminalisNucleus stria terminalisAnxiety-related disordersBed nucleusClinical heterogeneityComorbid anxietyWhole brainAmygdalaIntrinsic connectivityRSFCNathan Kline Institute-Rockland SampleAnticipatory anxietyBNSTGroup differencesNeural markersDisordersPatientsTerminalisImaging resultsCurrent findings
2013
Ventromedial prefrontal cortex and the regulation of physiological arousal
Zhang S, Hu S, Chao HH, Ide JS, Luo X, Farr OM, Li CS. Ventromedial prefrontal cortex and the regulation of physiological arousal. Social Cognitive And Affective Neuroscience 2013, 9: 900-908. PMID: 23620600, PMCID: PMC4090954, DOI: 10.1093/scan/nst064.Peer-Reviewed Original ResearchConceptsSkin conductance levelVentromedial prefrontal cortexPrefrontal cortexDorsal anterior cingulate cortexCausal roleAnterior cingulate cortexFunctional magnetic resonance imagingMagnetic resonance imagingCerebral blood oxygenationSkin conductance measurementsHealthy adultsPhysiological arousalUnderstanding of dysfunctionCingulate cortexResonance imagingBrain regionsBlood oxygenationAnxiety disordersAltered controlCortexGranger causality analysisSkin conductance responsesBehavioral tasksPhasic skin conductance responsesSkin conductance
2000
Perceptual alternation in obsessive compulsive disorder — implications for a role of the cortico-striatal circuitry in mediating awareness
Li C, Chen M, Yang Y, Chang H, Liu C, Shen S, Chen C. Perceptual alternation in obsessive compulsive disorder — implications for a role of the cortico-striatal circuitry in mediating awareness. Behavioural Brain Research 2000, 111: 61-69. PMID: 10840132, DOI: 10.1016/s0166-4328(00)00140-6.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnxiety DisordersAttentionAwarenessBrain MappingCerebral CortexCorpus StriatumDepth PerceptionFemaleFrontal LobeHumansMaleNerve NetNeural InhibitionObsessive-Compulsive DisorderOptical IllusionsOrientationPattern Recognition, VisualPerceptual DisordersReaction TimeSaccadesSynaptic TransmissionConceptsCortico-striatal circuitryPerceptual alternationsPerceptual reversalsHamilton anxiety scoreFronto-striatal circuitryPerceptual alternation ratesYale-Brown Obsessive CompulsiveGeneralized anxiety disorderEtiology of OCDNormal controlsNormal subjectsAlternative perceptsFunctional aberrationsSchröder staircaseBehavioral tasksEye fixationsAnxiety disordersObsessive-CompulsiveAnxiety scoresAlternation rateBehavioral manifestationsInhibitory functionBrain statesOCDDifferent thoughts