2018
Trajectories after first‐episode psychosis: Complement to ambiguous outcomes of long‐term antipsychotic treatment by exploring a few hidden cases
Liu C, Lin Y, Liu C, Hsieh M, Chien Y, Hwang T, Hwu H. Trajectories after first‐episode psychosis: Complement to ambiguous outcomes of long‐term antipsychotic treatment by exploring a few hidden cases. Early Intervention In Psychiatry 2018, 13: 895-901. PMID: 29927087, DOI: 10.1111/eip.12696.Peer-Reviewed Original ResearchConceptsFirst-episode psychosisLong-term antipsychotic treatmentAntipsychotic treatmentRecurrence of psychotic symptomsCourse of chronic schizophreniaLow-dose antipsychoticsChronic schizophreniaDysthymic statesPsychotic symptomsDiagnostic stabilityWord lettersRemission criteriaPsychosisAmbiguous informationProbability of relapseCoping strategiesImpending relapseAmbiguous outcomesDiscontinued medicationAntipsychoticsPersonalized formulationsMedication adherencePsychosocial factorsEarly interventionGroup of patients
2013
Aripiprazole for Drug-Naive or Antipsychotic-Short-Exposure Subjects With Ultra-High Risk State and First-Episode Psychosis
Liu C, Chien Y, Hsieh M, Hwang T, Hwu H, Liu C. Aripiprazole for Drug-Naive or Antipsychotic-Short-Exposure Subjects With Ultra-High Risk State and First-Episode Psychosis. Journal Of Clinical Psychopharmacology 2013, 33: 18-23. PMID: 23277261, DOI: 10.1097/jcp.0b013e31827cb017.Peer-Reviewed Original ResearchConceptsFirst-episode psychosisUltra-high riskFirst-episode psychosis patientsDrug-naiveUltra-high risk stateUltra-high-risk patientsLow-dose aripiprazoleNegative symptom scoresPositive symptom scoresFlexible dosing strategyState of psychosisTreatment responseAntipsychotic therapyDrug-naive populationSevere psychopathologyUHR patientsFirst-episodeAripiprazoleAdverse eventsSymptom scoresPsychosisRisk stateConcomitant medicationsTarget doseClinical improvement
2010
Follow-up of subjects with suspected pre-psychotic state in Taiwan
Liu C, Lai M, Liu C, Chiu Y, Hsieh M, Hwang T, Chien Y, Chen W, Hua M, Hsiung P, Huang Y, Hwu H. Follow-up of subjects with suspected pre-psychotic state in Taiwan. Schizophrenia Research 2010, 126: 65-70. PMID: 21112187, DOI: 10.1016/j.schres.2010.10.028.Peer-Reviewed Original ResearchConceptsFirst-episode psychosisPre-psychotic stateUHR subjectsRate of conversion to psychosisUltra-high-risk groupConversion to psychosisPsychosis risk syndromeFollow-upRisk groupsIntermediate-risk groupNegative symptomsSchizophreniform disorderSchizoaffective disorderPsychotic disordersAntipsychotic useBipolar disorderClinical interviewFollow-up of subjectsOutcomes of subjectsCommunity-based populationRisk syndromeDiagnostic categoriesPsychosisClinical attentionUHRCreating a Platform to Bridge Service and Research for Early Psychosis
Liu C, Hwu H, Chiu Y, Lai M, Tseng H. Creating a Platform to Bridge Service and Research for Early Psychosis. Journal Of The Formosan Medical Association 2010, 109: 543-549. PMID: 20654794, DOI: 10.1016/s0929-6646(10)60089-7.Peer-Reviewed Original ResearchConceptsFull-blown psychosisRisk subjectsPsychopathology progressProspective studyEarly psychosisPerceptual disturbancesLongitudinal prospective studyPsychosisIdentification of subjectsStudy teamEarly identification of subjectsYear oldsEarly interventionClinical entityClinical severityClinicRiskSubjectsAppointmentInterventionYearsIll-definedTeamEnrollment