2006
Familial Aggregation of Insulin Resistance in First-Degree Relatives of Patients With Nonalcoholic Fatty Liver Disease
Abdelmalek M, Liu C, Shuster J, Nelson D, Asal N. Familial Aggregation of Insulin Resistance in First-Degree Relatives of Patients With Nonalcoholic Fatty Liver Disease. Clinical Gastroenterology And Hepatology 2006, 4: 1162-1169. PMID: 16901766, DOI: 10.1016/j.cgh.2006.06.001.Peer-Reviewed Original ResearchConceptsNonalcoholic fatty liver diseaseFirst-degree relativesFatty liver diseaseCryptogenic cirrhosisDiabetes mellitusLiver diseaseGenetic predispositionRisk of DMFamilial clusteringFirst-degree family membersBody mass indexInsulin resistance syndromeSignificant survival differenceExpression of IRWarrants further investigationNAFLD patientsMass indexResistance syndromeInsulin resistanceMedical historySurvival differencesHealthy controlsCardiac diseaseRenal stonesFamilial aggregation studies
2005
40 THE NATURAL HISTORY OF CRYPTOGENIC CIRRHOSIS FOLLOWING ORTHOTOPIC LIVER TRANSPLANTATION: A HISTORICAL COHORT STUDY
Abdelmalek M, Mudaliar K, Liu C, Reed A, Nelson D, Asal N, Stacpoole P. 40 THE NATURAL HISTORY OF CRYPTOGENIC CIRRHOSIS FOLLOWING ORTHOTOPIC LIVER TRANSPLANTATION: A HISTORICAL COHORT STUDY. Journal Of Investigative Medicine 2005, 53: s393. DOI: 10.2310/6650.2005.00205.39.Peer-Reviewed Original ResearchNonalcoholic fatty liver diseaseLiver transplantationCryptogenic cirrhosisSteatosis gradeClinical dataMean age 53Repeat liver transplantationYr post-LTFatty liver diseaseInsulin resistance syndromeCardiovascular disease deathsPost-LTPre-LTMELD scoreGlycemic controlHDL cholesterolLiver biopsyInflammatory activityLDL cholesterolLiver diseaseDisease deathsResistance syndromeSingle pathologistClinicopathologic correlationRisk factors