1996
Neurodevelopmental outcome at 36 months' corrected age of preterm infants in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial.
Ment L, Vohr B, Oh W, Scott D, Allan W, Westerveld M, Duncan C, Ehrenkranz R, Katz K, Schneider K, Makuch R. Neurodevelopmental outcome at 36 months' corrected age of preterm infants in the Multicenter Indomethacin Intraventricular Hemorrhage Prevention Trial. Pediatrics 1996, 98: 714-8. PMID: 8885951, DOI: 10.1542/peds.98.4.714.Peer-Reviewed Original ResearchMeSH KeywordsCerebral HemorrhageChild DevelopmentChild, PreschoolChi-Square DistributionCyclooxygenase InhibitorsHumansIndomethacinInfantInfant, NewbornInfant, PrematureInfant, Premature, DiseasesInfant, Very Low Birth WeightIntelligence TestsNeurologic ExaminationUltrasonography, Doppler, TranscranialConceptsLow-dose indomethacinMonths' corrected ageIntraventricular hemorrhageCorrected ageNeurodevelopmental followLong-term neurodevelopmental followLow birth weight infantsLow birth weight neonatesBirth weight infantsMean gestational ageBirth weight neonatesStandard neurologic examinationAdverse cognitive outcomesIncidence of deafnessDose indomethacinWeight infantsPreterm infantsProspective trialWeight neonatesCranial ultrasoundEarly administrationNeurodevelopmental outcomesNeurologic examinationCerebral palsyGestational age
1994
Low-dose indomethacin and prevention of intraventricular hemorrhage: a multicenter randomized trial.
Ment L, Ehrenkranz R, Duncan C, Scott D, Taylor K, Katz K, Schneider K, Makuch R, Oh W, Vohr B, Philip A, Allan W. Low-dose indomethacin and prevention of intraventricular hemorrhage: a multicenter randomized trial. Pediatrics 1994, 93: 543-50. PMID: 8134206, DOI: 10.1542/peds.93.4.543.Peer-Reviewed Original ResearchConceptsLow birth weight neonatesSeverity of IVHBirth weight neonatesIntraventricular hemorrhageWeight neonatesDose indomethacinBirth weightGrade 4 intraventricular hemorrhageSerial cranial ultrasound examinationsSignificant adverse drug eventsPercent of neonatesPlacebo-controlled trialPatent ductus arteriosusCranial ultrasound examinationMajor risk factorAdverse drug eventsHours of ageFirst postnatal dayDuctal closureProphylactic indomethacinApgar scoreNeurodevelopmental handicapParenchymal involvementPlacebo groupAdverse events
1988
Randomized low-dose indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight neonates
Ment L, Duncan C, Ehrenkranz R, Kleinman C, Taylor K, Scott D, Gettner P, Sherwonit E, Williams J. Randomized low-dose indomethacin trial for prevention of intraventricular hemorrhage in very low birth weight neonates. The Journal Of Pediatrics 1988, 112: 948-955. PMID: 3373405, DOI: 10.1016/s0022-3476(88)80225-7.Peer-Reviewed Original ResearchConceptsIntraventricular hemorrhageGerminal matrixPostnatal hoursUrinary outputDay 5Placebo-controlled prospective trialLow birth weight neonatesDuctus arteriosus shuntIndomethacin-treated infantsSerum indomethacin levelsBirth weight neonatesCardiac ultrasound studiesAdequate urinary outputGroups of infantsIndomethacin trialStudy medicationApgar scorePreterm neonatesProspective trialWeight neonatesDuctus arteriosusGestational ageSerum electrolytesBirth weightPatent ductus
1985
Neurodevelopmental assessment of very low birth weight neonates: Effect of germinal matrix and intraventricular hemorrhage
Ment L, Scott D, Ehrenkranz R, Duncan C. Neurodevelopmental assessment of very low birth weight neonates: Effect of germinal matrix and intraventricular hemorrhage. Pediatric Neurology 1985, 1: 164-168. PMID: 3880401, DOI: 10.1016/0887-8994(85)90058-x.Peer-Reviewed Original ResearchConceptsGMH/IVHIntraventricular hemorrhageNeurodevelopmental assessmentGerminal matrixSurviving infantsNeonatal germinal matrix hemorrhageNewborn Special Care UnitLow birth weight neonatesBirth weight neonatesGerminal matrix hemorrhageMajor neurologic abnormalitiesSpecial care unitsNon-hemorrhage groupWeight neonatesCare unitGroup infantsPostnatal hoursNeurologic abnormalitiesBirth weightSevere gradesHemorrhageDevelopmental scoresBayley ScalesInfantsInfant development
1984
Posthemorrhagic hydrocephalus. Low incidence in very low birth weight neonates with intraventricular hemorrhage.
Ment L, Duncan C, Scott D, Ehrenkranz R. Posthemorrhagic hydrocephalus. Low incidence in very low birth weight neonates with intraventricular hemorrhage. Journal Of Neurosurgery 1984, 60: 343-7. PMID: 6693962, DOI: 10.3171/jns.1984.60.2.0343.Peer-Reviewed Original ResearchConceptsIntraventricular hemorrhagePosthemorrhagic hydrocephalusLong-term neurodevelopmental handicapsNewborn Special Care UnitLow birth weight neonatesCranial ultrasound scanningCranial ultrasound studiesBirth weight neonatesBirth weight rangeCongenital aqueductal stenosisElevated intracranial pressureSpecial care unitsOccipitofrontal head circumferenceNon-hemorrhage groupNeurodevelopmental handicapPreterm infantsWeight neonatesCare unitPostnatal hoursAqueductal stenosisBirth weightEqual incidenceIntracranial pressureHead circumferenceGerminal matrix