2024
Measurement invariance of the Perceived Stress Scale across race, sex, and time, and differential impacts on cocaine use treatment outcomes
Schick M, Kiluk B, Nich C, LaPaglia D, Haeny A. Measurement invariance of the Perceived Stress Scale across race, sex, and time, and differential impacts on cocaine use treatment outcomes. Journal Of Substance Use And Addiction Treatment 2024, 166: 209493. PMID: 39151798, PMCID: PMC11392621, DOI: 10.1016/j.josat.2024.209493.Peer-Reviewed Original ResearchCocaine use disorderPerceived Stress ScaleTreatment retentionMeasurement invarianceTreatment outcomesSubstance use treatment outcomesStress ScalePredicting treatment retentionSelf-efficacyCoping self-efficacyTwo-factor modelInfluence treatment outcomeCocaine abuse/dependenceDSM-IVUse disorderCocaine useBetween-group differencesMetric invarianceScalar invarianceTwo-factorCocainePharmacological treatmentFactor analysisDifferential impactAbuse/dependence
2020
Measurement invariance of the Barratt Impulsiveness Scale across black and white adults with cocaine use disorder
Haeny AM, Kiluk BD, Nich C, LaPaglia DM, Carroll KM. Measurement invariance of the Barratt Impulsiveness Scale across black and white adults with cocaine use disorder. Addictive Behaviors 2020, 114: 106721. PMID: 33162231, PMCID: PMC7802511, DOI: 10.1016/j.addbeh.2020.106721.Peer-Reviewed Original ResearchConceptsBarratt Impulsiveness ScaleHigher motor impulsivenessCocaine use disorderMeasurement invarianceMotor impulsivenessImpulsiveness ScaleBlack subsampleUse disordersDays abstinentMulti-group confirmatory factor analysisTreatment retentionCocaine abuse/dependenceCocaine treatment outcomesFactor analysisConfirmatory factor analysisAbuse/dependenceImpulsivityCocaine-negative urinesImpulsivenessBivariate correlationsWhite subsampleAbstinentOverall sampleTotal sampleAdults
2017
Drug Stroop: Mechanisms of response to computerized cognitive behavioral therapy for cocaine dependence in a randomized clinical trial
DeVito EE, Kiluk BD, Nich C, Mouratidis M, Carroll KM. Drug Stroop: Mechanisms of response to computerized cognitive behavioral therapy for cocaine dependence in a randomized clinical trial. Drug And Alcohol Dependence 2017, 183: 162-168. PMID: 29258028, PMCID: PMC5803332, DOI: 10.1016/j.drugalcdep.2017.10.022.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyDrug-related stimuliAttentional biasDrug-related cuesCognitive controlStroop effectStroop taskBehavioral therapyTreatment componentsComputer-based cognitive behavioral therapyComputerized cognitive behavioral therapyPoor cognitive controlCognitive control processesExecutive cognitive controlSubstance use severityCocaine use outcomesCocaine use disorderResponse inhibitionUse severityUse outcomesControl processGreater engagementTreatment retentionCBT4CBTCocaine dependence
2016
Carvedilol does not reduce cocaine use in methadone-maintained cocaine users
Sofuoglu M, Poling J, Babuscio T, Gonsai K, Severino K, Nich C, Carroll KM. Carvedilol does not reduce cocaine use in methadone-maintained cocaine users. Journal Of Substance Use And Addiction Treatment 2016, 73: 63-69. PMID: 28017186, PMCID: PMC5193370, DOI: 10.1016/j.jsat.2016.11.005.Peer-Reviewed Original ResearchConceptsEfficacy of carvedilolCocaine-positive urinesSignificant group differencesCocaine use disorderCocaine useOpioid usePositive urineGroup differencesOpioid-positive urinesCAR groupMain outcome measuresUrine drug screeningOpioid-dependent participantsSelf-reported drug useSelf-reported daysOverall treatment effectCocaine-dependent participantsTreatment armsAdrenergic blockersTreatment responseOutcome measuresPlaceboWithdrawal severityStudy participationTreatment retention
2014
Computer-Assisted Delivery of Cognitive-Behavioral Therapy: Efficacy and Durability of CBT4CBT Among Cocaine-Dependent Individuals Maintained on Methadone
Carroll KM, Kiluk BD, Nich C, Gordon MA, Portnoy GA, Marino DR, Ball SA. Computer-Assisted Delivery of Cognitive-Behavioral Therapy: Efficacy and Durability of CBT4CBT Among Cocaine-Dependent Individuals Maintained on Methadone. American Journal Of Psychiatry 2014, 171: 436-444. PMID: 24577287, PMCID: PMC4042674, DOI: 10.1176/appi.ajp.2013.13070987.Peer-Reviewed Original ResearchConceptsCocaine-dependent individualsCognitive behavioral therapyMethadone maintenanceCommunity-based outpatient clinicsPrevious pilot trialMethadone maintenance programStandard methadone maintenanceDisseminable strategyDefinitive trialOutpatient clinicClinical trialsEffective adjunctPilot trialTreatment terminationTreatment retentionBetter outcomesConsecutive weeksCBT4CBTWeekly accessAddiction treatmentDurable effectsTrialsSubstance usersStatistical significanceMethadone
2009
A Multisite Randomized Effectiveness Trial of Motivational Enhancement Therapy for Spanish-Speaking Substance Users
Carroll KM, Martino S, Ball SA, Nich C, Frankforter T, Anez LM, Paris M, Suarez-Morales L, Szapocznik J, Miller WR, Rosa C, Matthews J, Farentinos C. A Multisite Randomized Effectiveness Trial of Motivational Enhancement Therapy for Spanish-Speaking Substance Users. Journal Of Consulting And Clinical Psychology 2009, 77: 993-999. PMID: 19803579, PMCID: PMC2792592, DOI: 10.1037/a0016489.Peer-Reviewed Original ResearchConceptsMotivational enhancement therapyEnhancement therapySubstance useSubstance usersRandomized Effectiveness TrialIndividual sessionsCurrent substance useX time interactionTreatment condition interactionCondition x time interactionSubstance use problemsClinical trialsEffectiveness trialTreatment exposureTherapy phaseTreatment retentionTreatment sessionsHispanic adultsTherapyHeterogeneous groupHispanic individualsTime interactionIndividual treatmentTrialsUse problems
2008
Enduring effects of a computer-assisted training program for cognitive behavioral therapy: A 6-month follow-up of CBT4CBT
Carroll KM, Ball SA, Martino S, Nich C, Babuscio TA, Rounsaville BJ. Enduring effects of a computer-assisted training program for cognitive behavioral therapy: A 6-month follow-up of CBT4CBT. Drug And Alcohol Dependence 2008, 100: 178-181. PMID: 19041197, PMCID: PMC2742309, DOI: 10.1016/j.drugalcdep.2008.09.015.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyBehavioral therapyComputer-assisted training programSubstance dependenceComputer-based trainingSubstance use outcomesComputer-assisted versionDrug useEnduring effectCBT4CBTUse outcomesRandomized clinical trialsTreatment retentionDurability of effectTraining programOutpatient communityStudy treatmentStandard treatmentOutpatient treatmentClinical trialsTreatment conditionsParticipantsSignificant differencesTreatmentRegression analysisComputer-Assisted Delivery of Cognitive-Behavioral Therapy for Addiction: A Randomized Trial of CBT4CBT
Carroll KM, Ball SA, Martino S, Nich C, Babuscio TA, Nuro KF, Gordon MA, Portnoy GA, Rounsaville BJ. Computer-Assisted Delivery of Cognitive-Behavioral Therapy for Addiction: A Randomized Trial of CBT4CBT. American Journal Of Psychiatry 2008, 165: 881-888. PMID: 18450927, PMCID: PMC2562873, DOI: 10.1176/appi.ajp.2008.07111835.Peer-Reviewed Original Research
2007
Enhancing brief cognitive-behavioral therapy with motivational enhancement techniques in cocaine users
McKee SA, Carroll KM, Sinha R, Robinson JE, Nich C, Cavallo D, O’Malley S. Enhancing brief cognitive-behavioral therapy with motivational enhancement techniques in cocaine users. Drug And Alcohol Dependence 2007, 91: 97-101. PMID: 17573205, PMCID: PMC2386854, DOI: 10.1016/j.drugalcdep.2007.05.006.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyMotivational enhancement therapyBrief cognitive behavioral therapyMotivational enhancement techniquesSpecific treatment componentsCocaine usersExpectations of successMotivational interviewing techniquesCBT conditionCocaine useEnhancement therapyTreatment componentsIntervention paradigmInterviewing techniquesTherapy processMixed supportCocaine abuseInitial sessionTreatment retentionThree-sessionGreater desireGreat difficultyTreatment conditionsTreatment sessionsProcess measures
2006
The Use of Contingency Management and Motivational/Skills-Building Therapy to Treat Young Adults With Marijuana Dependence
Carroll KM, Easton CJ, Nich C, Hunkele KA, Neavins TM, Sinha R, Ford HL, Vitolo SA, Doebrick CA, Rounsaville BJ. The Use of Contingency Management and Motivational/Skills-Building Therapy to Treat Young Adults With Marijuana Dependence. Journal Of Consulting And Clinical Psychology 2006, 74: 955-966. PMID: 17032099, PMCID: PMC2148500, DOI: 10.1037/0022-006x.74.5.955.Peer-Reviewed Original ResearchConceptsMET/CBTYoung adultsSkill-building interventionsDrug counselingSignificant main effectIndividual drug counselingUrine specimensMarijuana dependenceCriminal justice systemTreatment attendanceCBTMarijuana useContingency managementSession attendanceTreatment retentionJustice systemMain effectIncentives contingentTreatment conditionsAdultsParticipantsAttendanceInterventionContingentTherapy
2004
Ethnic Differences in Substance Abuse Treatment Retention, Compliance, and Outcome From Two Clinical Trials
Milligan CO, Nich C, Carroll KM. Ethnic Differences in Substance Abuse Treatment Retention, Compliance, and Outcome From Two Clinical Trials. Psychiatric Services 2004, 55: 167-173. PMID: 14762242, PMCID: PMC3666311, DOI: 10.1176/appi.ps.55.2.167.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceAntidepressive Agents, TricyclicBlack PeopleCocaine-Related DisordersCognitive Behavioral TherapyCombined Modality TherapyConnecticutDesipramineDisulfiramEnzyme InhibitorsFemaleHumansMalePatient CompliancePatient DropoutsRetrospective StudiesTreatment OutcomeWhite PeopleConceptsCocaine use outcomesTreatment expectationsTreatment retentionAfrican AmericansUse outcomesExpectations of treatmentSubstance abuse treatment retentionDays of treatmentDifferent behavioral treatmentsClinical trialsPretreatment characteristicsAfrican American participantsMedication componentsCocaine dependence
2002
‘Intention-to-treat’ meets ‘missing data’: implications of alternate strategies for analyzing clinical trials data
Nich C, Carroll KM. ‘Intention-to-treat’ meets ‘missing data’: implications of alternate strategies for analyzing clinical trials data. Drug And Alcohol Dependence 2002, 68: 121-130. PMID: 12234641, PMCID: PMC3651592, DOI: 10.1016/s0376-8716(02)00111-4.Peer-Reviewed Original ResearchConceptsEffectiveness of treatmentTreat analysisClinical trialsRandomized clinical trialsClinical trial dataStudy treatmentProtocol violationsTreat strategyTreatment retentionPoint of dropoutTime-varying covariatesTrial dataCocaine dependenceIntended durationParticipant dropoutRelative efficacyTrialsTreatmentMultiple analytic strategiesRetention outcomesDurationFull durationStrategy 1Analytic strategiesSubstantial levels
2001
Targeting Behavioral Therapies to Enhance Naltrexone Treatment of Opioid Dependence: Efficacy of Contingency Management and Significant Other Involvement
Carroll KM, Ball SA, Nich C, O'Connor PG, Eagan DA, Frankforter TL, Triffleman EG, Shi J, Rounsaville BJ. Targeting Behavioral Therapies to Enhance Naltrexone Treatment of Opioid Dependence: Efficacy of Contingency Management and Significant Other Involvement. JAMA Psychiatry 2001, 58: 755-761. PMID: 11483141, PMCID: PMC3651594, DOI: 10.1001/archpsyc.58.8.755.Peer-Reviewed Original ResearchConceptsDrug-free urine specimensNaltrexone treatmentFamily counseling sessionsContingency managementOpioid dependenceTreatment retentionUrine specimensBehavioral therapyOpioid-dependent individualsCounseling sessionsDrug use outcomesSubstance abuse outcomesNaltrexone complianceNaltrexone therapyOpioid useAvailable pharmacotherapiesMedication complianceSpecific pharmacotherapySignificant improvementTherapyUse outcomesAbuse outcomesPrincipal outcomePharmacotherapyTreatment
1995
Alexithymia in Cocaine Abusers
Keller D, Carroll K, Nich C, Rounsaville B. Alexithymia in Cocaine Abusers. American Journal On Addictions 1995, 4: 234-244. DOI: 10.3109/10550499509038108.Peer-Reviewed Original ResearchCognitive-behavioral relapse preventionIdentification of affectNonalexithymic subjectsAmbulatory cocaine abusersAlexithymic subjectsToronto Alexithymia ScaleSubstance-related problemsCocaine abusersCurrent distressAxis I DisordersRelapse preventionAlexithymia ScaleCocaine outcomesAlexithymic rangeTreatment retentionAlexithymic patientsDemographic variablesAlexithymiaI disordersCocaine use
1994
Psychotherapy and Pharmacotherapy for Ambulatory Cocaine Abusers
Carroll KM, Rounsaville BJ, Gordon LT, Nich C, Jatlow P, Bisighini RM, Gawin FH. Psychotherapy and Pharmacotherapy for Ambulatory Cocaine Abusers. JAMA Psychiatry 1994, 51: 177-187. PMID: 8122955, DOI: 10.1001/archpsyc.1994.03950030013002.Peer-Reviewed Original ResearchConceptsClinical managementCocaine useCocaine abusersRelapse preventionAmbulatory cocaine abusersWeeks of treatmentForm of treatmentHigh-severity patientsInitiation trialsAbstinence initiationBaseline severityClinical trialsEffective treatmentTreatment retentionBetter outcomesCocaine abusePharmacotherapyDepressed subjectsPlaceboDesipramine hydrochlorideSpecialized treatmentDesipraminePreventionGreater reductionDistinct subgroups