2002
Contingency Management to Enhance Naltrexone Treatment of Opioid Dependence: A Randomized Clinical Trial of Reinforcement Magnitude
Carroll KM, Sinha R, Nich C, Babuscio T, Rounsaville BJ. Contingency Management to Enhance Naltrexone Treatment of Opioid Dependence: A Randomized Clinical Trial of Reinforcement Magnitude. Experimental And Clinical Psychopharmacology 2002, 10: 54-63. PMID: 11866252, DOI: 10.1037/1064-1297.10.1.54.Peer-Reviewed Original ResearchConceptsNaltrexone treatmentContingency managementOpioid-dependent individualsSignificant reductionReinforcement magnitudeOpioid useAvailable pharmacotherapiesNaltrexone maintenanceOpioid dependenceClinical trialsCM groupBehavioral therapyNaltrexoneTreatmentCM conditionRelative benefitsParticipantsPharmacotherapyTherapyTrialsWeeks
2001
Targeting Behavioral Therapies to Enhance Naltrexone Treatment of Opioid Dependence: Efficacy of Contingency Management and Significant Other Involvement
Carroll KM, Ball SA, Nich C, O'Connor PG, Eagan DA, Frankforter TL, Triffleman EG, Shi J, Rounsaville BJ. Targeting Behavioral Therapies to Enhance Naltrexone Treatment of Opioid Dependence: Efficacy of Contingency Management and Significant Other Involvement. JAMA Psychiatry 2001, 58: 755-761. PMID: 11483141, PMCID: PMC3651594, DOI: 10.1001/archpsyc.58.8.755.Peer-Reviewed Original ResearchConceptsDrug-free urine specimensNaltrexone treatmentFamily counseling sessionsContingency managementOpioid dependenceTreatment retentionUrine specimensBehavioral therapyOpioid-dependent individualsCounseling sessionsDrug use outcomesSubstance abuse outcomesNaltrexone complianceNaltrexone therapyOpioid useAvailable pharmacotherapiesMedication complianceSpecific pharmacotherapySignificant improvementTherapyUse outcomesAbuse outcomesPrincipal outcomePharmacotherapyTreatment
1997
Contribution of the Therapeutic Alliance to Outcome in Active Versus Control Psychotherapies
Carroll K, Nich C, Rounsaville B. Contribution of the Therapeutic Alliance to Outcome in Active Versus Control Psychotherapies. Journal Of Consulting And Clinical Psychology 1997, 65: 510-514. PMID: 9170775, DOI: 10.1037/0022-006x.65.3.510.Peer-Reviewed Original Research
1994
One-Year Follow-up of Psychotherapy and Pharmacotherapy for Cocaine Dependence: Delayed Emergence of Psychotherapy Effects
Carroll KM, Rounsaville BJ, Nich C, Gordon LT, Wirtz PW, Gawin F. One-Year Follow-up of Psychotherapy and Pharmacotherapy for Cocaine Dependence: Delayed Emergence of Psychotherapy Effects. JAMA Psychiatry 1994, 51: 989-997. PMID: 7979888, DOI: 10.1001/archpsyc.1994.03950120061010.Peer-Reviewed Original ResearchConceptsCognitive-behavioral relapse preventionRelapse preventionAmbulatory cocaine abusersCocaine dependenceSupportive clinical managementCoping skillsCocaine usePsychotherapy effectsLess cocaine useSubstance abusersPsychotherapyFull sampleCocaine abusersEffects regression modelsRandom effects regression modelsAbusersOutpatient treatmentOne-year followPosttreatment levelsSubject implementationTime effectsPharmacotherapySkillsAbstinenceRelative abilityPsychotherapy and Pharmacotherapy for Ambulatory Cocaine Abusers
Carroll KM, Rounsaville BJ, Gordon LT, Nich C, Jatlow P, Bisighini RM, Gawin FH. Psychotherapy and Pharmacotherapy for Ambulatory Cocaine Abusers. JAMA Psychiatry 1994, 51: 177-187. PMID: 8122955, DOI: 10.1001/archpsyc.1994.03950030013002.Peer-Reviewed Original ResearchConceptsClinical managementCocaine useCocaine abusersRelapse preventionAmbulatory cocaine abusersWeeks of treatmentForm of treatmentHigh-severity patientsInitiation trialsAbstinence initiationBaseline severityClinical trialsEffective treatmentTreatment retentionBetter outcomesCocaine abusePharmacotherapyDepressed subjectsPlaceboDesipramine hydrochlorideSpecialized treatmentDesipraminePreventionGreater reductionDistinct subgroups