2017
Effect of computerized cognitive behavioral therapy on acquisition of coping skills among cocaine-dependent individuals enrolled in methadone maintenance
Kiluk BD, DeVito EE, Buck MB, Hunkele K, Nich C, Carroll KM. Effect of computerized cognitive behavioral therapy on acquisition of coping skills among cocaine-dependent individuals enrolled in methadone maintenance. Journal Of Substance Use And Addiction Treatment 2017, 82: 87-92. PMID: 29021121, PMCID: PMC5687291, DOI: 10.1016/j.jsat.2017.09.011.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyCocaine-dependent individualsHigh-risk situationsBehavioral therapyVerbal responsesComputerized cognitive behavioral therapyAbstinence outcomesComputerized CBT programParticipants' verbal responsesRole-play assessmentComputer-based trainingCertain high-risk situationsStandard methadone treatmentSubstance use disordersConsistent statistical supportCBT programMethadone treatmentMethadone maintenanceDependent individualsPlay assessmentPrior findingsClinical trialsTreatment periodUse disordersSubstance users
2016
Alexithymia and Addiction: A Review and Preliminary Data Suggesting Neurobiological Links to Reward/Loss Processing
Morie KP, Yip SW, Nich C, Hunkele K, Carroll KM, Potenza MN. Alexithymia and Addiction: A Review and Preliminary Data Suggesting Neurobiological Links to Reward/Loss Processing. Current Addiction Reports 2016, 3: 239-248. PMID: 27695665, PMCID: PMC5040368, DOI: 10.1007/s40429-016-0097-8.Peer-Reviewed Original ResearchReward/loss processingSubstance use disordersLoss processingRole of alexithymiaPreliminary fMRI dataUse disordersCocaine-dependent individualsEmotional awarenessNeural correlatesReward anticipationNeurobiological correlatesAlexithymiaNeurobiological linkFMRI dataSubstance useSubstance dependenceCocaine dependenceAddictionCorrelatesIndividualsDisordersProcessingAnticipationImpairment
2014
Only connect: The working alliance in computer-based cognitive behavioral therapy
Kiluk BD, Serafini K, Frankforter T, Nich C, Carroll KM. Only connect: The working alliance in computer-based cognitive behavioral therapy. Behaviour Research And Therapy 2014, 63: 139-146. PMID: 25461789, PMCID: PMC4408209, DOI: 10.1016/j.brat.2014.10.003.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyTechnology-based interventionsWorking Alliance InventoryBehavioral therapyComputer-based cognitive behavioral therapyCocaine-dependent individualsCocaine use outcomesEfficacy of computerDays abstinentFace psychotherapyUse outcomesSimilar psychometric characteristicsPsychometric characteristicsSubscale scoresAlliance InventoryTherapistsPreliminary findingsTotal scoreInterventionTreatment outcomesCBTScoresAbstinentPsychotherapyLittle evidenceComputer-Assisted Delivery of Cognitive-Behavioral Therapy: Efficacy and Durability of CBT4CBT Among Cocaine-Dependent Individuals Maintained on Methadone
Carroll KM, Kiluk BD, Nich C, Gordon MA, Portnoy GA, Marino DR, Ball SA. Computer-Assisted Delivery of Cognitive-Behavioral Therapy: Efficacy and Durability of CBT4CBT Among Cocaine-Dependent Individuals Maintained on Methadone. American Journal Of Psychiatry 2014, 171: 436-444. PMID: 24577287, PMCID: PMC4042674, DOI: 10.1176/appi.ajp.2013.13070987.Peer-Reviewed Original ResearchConceptsCocaine-dependent individualsCognitive behavioral therapyMethadone maintenanceCommunity-based outpatient clinicsPrevious pilot trialMethadone maintenance programStandard methadone maintenanceDisseminable strategyDefinitive trialOutpatient clinicClinical trialsEffective adjunctPilot trialTreatment terminationTreatment retentionBetter outcomesConsecutive weeksCBT4CBTWeekly accessAddiction treatmentDurable effectsTrialsSubstance usersStatistical significanceMethadone
2013
Smokers Versus Snorters: Do Treatment Outcomes Differ According to Route of Cocaine Administration?
Kiluk BD, Babuscio TA, Nich C, Carroll KM. Smokers Versus Snorters: Do Treatment Outcomes Differ According to Route of Cocaine Administration? Experimental And Clinical Psychopharmacology 2013, 21: 490-498. PMID: 24364538, PMCID: PMC3943602, DOI: 10.1037/a0034173.Peer-Reviewed Original ResearchConceptsTreatment outcomesCocaine administrationAddiction Severity Index composite scoresIntranasal usersComposite scoreRoute of administrationCocaine use outcomesPrimary routeIntranasal routeClinical trialsSustained abstinenceCocaine-dependent individualsTreatment phaseSmokersCocaine useStudy periodAdministrationUse outcomesSeverity of problemsMaximal concentrationStatistical significanceASI domainsOutcomesDifferential changesCocaine
2012
Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: A randomized placebo-controlled trial
Carroll KM, Nich C, Shi JM, Eagan D, Ball SA. Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: A randomized placebo-controlled trial. Drug And Alcohol Dependence 2012, 126: 224-231. PMID: 22695473, PMCID: PMC3461119, DOI: 10.1016/j.drugalcdep.2012.05.019.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DeterrentsAlcohol DrinkingCocaine-Related DisordersCounselingDemographyDiagnostic and Statistical Manual of Mental DisordersDisulfiramDouble-Blind MethodFemaleFollow-Up StudiesHumansMaleMethadoneNarcoticsOpiate Substitution TreatmentPatient ComplianceRegression AnalysisSelf-Help GroupsSocioeconomic FactorsSubstance Abuse DetectionTreatment OutcomeConceptsMethadone maintenance programEfficacy of disulfiramAlcohol use disorderCocaine useStandard counselingUse disordersCommunity-based methadone maintenance programRandomized placebo-controlled trialPlacebo-controlled trialCurrent alcohol use disorderTwelve-step facilitationCocaine-negative urinesLess cocaine useMethadone maintenanceStep FacilitationCocaine-dependent individualsPlaceboBetter outcomesDisulfiram efficacyTreatment approachesFactorial trialDisulfiramMaintenance programRelative efficacyCocaine users
2005
Practice Makes Progress? Homework Assignments and Outcome in Treatment of Cocaine Dependence
Carroll KM, Nich C, Ball SA. Practice Makes Progress? Homework Assignments and Outcome in Treatment of Cocaine Dependence. Journal Of Consulting And Clinical Psychology 2005, 73: 749-755. PMID: 16173864, PMCID: PMC2365906, DOI: 10.1037/0022-006x.73.4.749.Peer-Reviewed Original Research
2004
Efficacy of Disulfiram and Cognitive Behavior Therapy in Cocaine-DependentOutpatients: A Randomized Placebo-Controlled Trial
Carroll KM, Fenton LR, Ball SA, Nich C, Frankforter TL, Shi J, Rounsaville BJ. Efficacy of Disulfiram and Cognitive Behavior Therapy in Cocaine-DependentOutpatients: A Randomized Placebo-Controlled Trial. JAMA Psychiatry 2004, 61: 264-272. PMID: 14993114, PMCID: PMC3675448, DOI: 10.1001/archpsyc.61.3.264.Peer-Reviewed Original ResearchConceptsCocaine useGeneral populationCocaine dependenceEfficacy of disulfiramUrine toxicology screenOutpatient substance abuse treatment programsBehavior therapyConcurrent alcohol useSubstance abuse treatment programsCurrent cocaine dependenceCognitive behavior therapyDisulfiram useRandomized PlaceboDisulfiram therapyMedication complianceToxicology screenIdentical capsulesEffective therapyPlaceboCocaine-dependent individualsSelf-reported frequencyPromising treatmentPlacebo conditionInterpersonal psychotherapyTherapy
1998
Treatment of cocaine and alcohol dependence with psychotherapy and disulfiram
Carroll KM, Nich C, Ball SA, McCance E, Rounsavile BJ. Treatment of cocaine and alcohol dependence with psychotherapy and disulfiram. Addiction 1998, 93: 713-727. PMID: 9692270, DOI: 10.1046/j.1360-0443.1998.9357137.x.Peer-Reviewed Original ResearchConceptsCognitive-behavioral treatmentAlcohol useClinical managementCocaine useConcurrent alcohol abuseDrug use disordersTreatment of cocaineCo-morbid disordersPromising treatment strategySubstance abuse treatment centersTreatment-seeking cocaine abusersUrine toxicologyDrug-dependent individualsContinuous abstinenceDisulfiram treatmentStep FacilitationTreatment strategiesCocaine-dependent individualsAlcohol abuseAlcohol abusersUse disordersTreatment centersSupportive psychotherapyAlcohol dependenceActive psychotherapy