2019
Randomized placebo-controlled trial of galantamine in individuals with cocaine use disorder
DeVito EE, Carroll KM, Babuscio T, Nich C, Sofuoglu M. Randomized placebo-controlled trial of galantamine in individuals with cocaine use disorder. Journal Of Substance Use And Addiction Treatment 2019, 107: 29-37. PMID: 31757262, PMCID: PMC6918721, DOI: 10.1016/j.jsat.2019.08.009.Peer-Reviewed Original ResearchConceptsCocaine use disorderSignificant treatment group differencesUse disordersEfficacy of galantamineTreatment-seeking cocaine usersCurrent cocaine use disordersGroup differencesCocaine use outcomesSample of individualsTreatment group differencesComorbid opioid use disorderMethadone-maintained individualsMemory capacityAbstinent individualsCocaine useCognitive improvementCognitive outcomesCocaine use reductionCognitive functionUse outcomesCocaine usersGalantamine groupIndividualsDisordersInitial promise
2012
Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: A randomized placebo-controlled trial
Carroll KM, Nich C, Shi JM, Eagan D, Ball SA. Efficacy of disulfiram and Twelve Step Facilitation in cocaine-dependent individuals maintained on methadone: A randomized placebo-controlled trial. Drug And Alcohol Dependence 2012, 126: 224-231. PMID: 22695473, PMCID: PMC3461119, DOI: 10.1016/j.drugalcdep.2012.05.019.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlcohol DeterrentsAlcohol DrinkingCocaine-Related DisordersCounselingDemographyDiagnostic and Statistical Manual of Mental DisordersDisulfiramDouble-Blind MethodFemaleFollow-Up StudiesHumansMaleMethadoneNarcoticsOpiate Substitution TreatmentPatient ComplianceRegression AnalysisSelf-Help GroupsSocioeconomic FactorsSubstance Abuse DetectionTreatment OutcomeConceptsMethadone maintenance programEfficacy of disulfiramAlcohol use disorderCocaine useStandard counselingUse disordersCommunity-based methadone maintenance programRandomized placebo-controlled trialPlacebo-controlled trialCurrent alcohol use disorderTwelve-step facilitationCocaine-negative urinesLess cocaine useMethadone maintenanceStep FacilitationCocaine-dependent individualsPlaceboBetter outcomesDisulfiram efficacyTreatment approachesFactorial trialDisulfiramMaintenance programRelative efficacyCocaine users
2007
Enhancing brief cognitive-behavioral therapy with motivational enhancement techniques in cocaine users
McKee SA, Carroll KM, Sinha R, Robinson JE, Nich C, Cavallo D, O’Malley S. Enhancing brief cognitive-behavioral therapy with motivational enhancement techniques in cocaine users. Drug And Alcohol Dependence 2007, 91: 97-101. PMID: 17573205, PMCID: PMC2386854, DOI: 10.1016/j.drugalcdep.2007.05.006.Peer-Reviewed Original ResearchConceptsCognitive behavioral therapyMotivational enhancement therapyBrief cognitive behavioral therapyMotivational enhancement techniquesSpecific treatment componentsCocaine usersExpectations of successMotivational interviewing techniquesCBT conditionCocaine useEnhancement therapyTreatment componentsIntervention paradigmInterviewing techniquesTherapy processMixed supportCocaine abuseInitial sessionTreatment retentionThree-sessionGreater desireGreat difficultyTreatment conditionsTreatment sessionsProcess measures
2004
Prize reinforcement contingency management for treating cocaine users: how low can we go, and with whom?
Petry NM, Tedford J, Austin M, Nich C, Carroll KM, Rounsaville BJ. Prize reinforcement contingency management for treating cocaine users: how low can we go, and with whom? Addiction 2004, 99: 349-360. PMID: 14982548, PMCID: PMC3709247, DOI: 10.1111/j.1360-0443.2003.00642.x.Peer-Reviewed Original ResearchConceptsStandard treatmentUrinalysis resultsNegative urinalysis resultsCM conditionCommunity-based treatment centersPositive urinalysis resultsCommunity-based settingsContingency management interventionSevere patientsNegative urine samplesTreatment periodCM interventionPatientsTreatment centersMore abstinenceDrug useCocaine useTreatment assignmentBeneficial effectsUrine samplesCocaine usersContingency managementTreatmentInterventionGoal-related activities