Naltrexone and Disulfiram in Patients With Alcohol Dependence and Current Depression
Petrakis I, Ralevski E, Nich C, Levinson C, Carroll K, Poling J, Rounsaville B. Naltrexone and Disulfiram in Patients With Alcohol Dependence and Current Depression. Journal Of Clinical Psychopharmacology 2007, 27: 160-165. PMID: 17414239, DOI: 10.1097/jcp.0b13e3180337fcb.Peer-Reviewed Original ResearchMeSH KeywordsAlcohol DeterrentsAlcoholismBipolar DisorderCocaine-Related DisordersComorbidityConnecticutDepressive Disorder, MajorDisulfiramDouble-Blind MethodDrug Therapy, CombinationFemaleGamma-GlutamyltransferaseGastrointestinal DiseasesHumansMaleMassachusettsMiddle AgedNaltrexoneNarcotic AntagonistsPsychiatric Status Rating ScalesPsychotic DisordersSchizophreniaStress Disorders, Post-TraumaticTreatment OutcomeVeteransConceptsPsychiatric symptomsAlcohol dependenceAlcohol use outcomesMajor depressionPsychiatric disordersVeterans Administration Outpatient ClinicHamilton Depression Rating ScaleAxis I psychiatric disordersCommon co-occurring disordersDouble-blind randomizationUse outcomesGamma-glutamyltransferase levelsDepression Rating ScaleFourth Edition criteriaDiagnosis of depressionCo-occurring disordersSpecific psychiatric symptomsTreatment of alcoholismAlcohol use disorderOpen randomizationAdverse eventsMedication groupSecondary outcomesPrimary outcomeMedication treatment