2020
Forced Zika Virus Infection of Culex pipiens Leads to Limited Virus Accumulation in Mosquito Saliva
Abbo SR, Vogels CBF, Visser TM, Geertsema C, van Oers MM, Koenraadt CJM, Pijlman GP. Forced Zika Virus Infection of Culex pipiens Leads to Limited Virus Accumulation in Mosquito Saliva. Viruses 2020, 12: 659. PMID: 32575394, PMCID: PMC7354520, DOI: 10.3390/v12060659.Peer-Reviewed Original ResearchConceptsZika virusGuillain-Barré syndromeZika virus infectionInfectious blood mealUrban transmission cyclesMosquito-borne pathogenMosquito salivaZIKV transmissionOral exposureVirus infectionCongenital microcephalySevere diseaseIntrathoracic injectionLarge outbreakVirus disseminationUsutu virusMidgut barrierBarrier functionMosquito midgutVirus transmissionSalivaBlood mealYellow fever mosquitoVector competenceVirusThe invasive Asian bush mosquito Aedes japonicus found in the Netherlands can experimentally transmit Zika virus and Usutu virus
Abbo SR, Visser TM, Wang H, Göertz GP, Fros JJ, Abma-Henkens MHC, Geertsema C, Vogels CBF, Koopmans MPG, Reusken CBEM, Hall-Mendelin S, Hall RA, van Oers MM, Koenraadt CJM, Pijlman GP. The invasive Asian bush mosquito Aedes japonicus found in the Netherlands can experimentally transmit Zika virus and Usutu virus. PLOS Neglected Tropical Diseases 2020, 14: e0008217. PMID: 32282830, PMCID: PMC7153878, DOI: 10.1371/journal.pntd.0008217.Peer-Reviewed Original ResearchConceptsZika virusUsutu virusFed mosquitoesMidgut barrierMosquito midgut barrierGuillain-Barré syndromeInfectious blood mealSevere neurological impairmentSevere congenital microcephalyField-collected AeWest Nile virusClinical manifestationsMild diseaseUSUV infectionNeurological impairmentCongenital microcephalyRNA responseVirus disseminationArboviral diseasesNile virusVirus transmissionDroplet feedingVirusFemale mosquitoesBlood meal
2019
Effect of overwintering on survival and vector competence of the West Nile virus vector Culex pipiens
Koenraadt CJM, Möhlmann TWR, Verhulst NO, Spitzen J, Vogels CBF. Effect of overwintering on survival and vector competence of the West Nile virus vector Culex pipiens. Parasites & Vectors 2019, 12: 147. PMID: 30917854, PMCID: PMC6437999, DOI: 10.1186/s13071-019-3400-4.Peer-Reviewed Original ResearchConceptsVector competencePipiens mosquitoesBiotype pipiensMosquito-borne virusLaboratory-reared CxReal-time PCROlder ageConclusionsThis studyCulex pipiens mosquitoesBiotype compositionLaboratory-reared mosquitoesNile virusLaboratory-reared femalesSurvivalMonthsPipiens biotypesTwo-thirdsCulex pipiensWNV transmissionWest Nile virus vector Culex pipiensBiotype molestusPipiens femalesWNVMosquitoesSpecies Cx
2017
Vector competence of northern and southern European Culex pipiens pipiens mosquitoes for West Nile virus across a gradient of temperatures
Vogels CBF, Göertz GP, Pijlman GP, Koenraadt CJM. Vector competence of northern and southern European Culex pipiens pipiens mosquitoes for West Nile virus across a gradient of temperatures. Medical And Veterinary Entomology 2017, 31: 358-364. PMID: 28752627, DOI: 10.1111/mve.12251.Peer-Reviewed Original Research
2015
Winter Activity and Aboveground Hybridization Between the Two Biotypes of the West Nile Virus Vector Culex pipiens
Vogels CB, van de Peppel LJ, van Vliet AJ, Westenberg M, Ibañez-Justicia A, Stroo A, Buijs JA, Visser TM, Koenraadt CJ. Winter Activity and Aboveground Hybridization Between the Two Biotypes of the West Nile Virus Vector Culex pipiens. Vector-Borne And Zoonotic Diseases 2015, 15: 619-626. PMID: 26394124, DOI: 10.1089/vbz.2015.1820.Peer-Reviewed Original Research