Maternal T-Cell Engraftment Interferes With Human Leukocyte Antigen Typing in Severe Combined Immunodeficiency
Liu C, Duffy B, Bednarski JJ, Calhoun C, Lay L, Rundblad B, Payton JE, Mohanakumar T. Maternal T-Cell Engraftment Interferes With Human Leukocyte Antigen Typing in Severe Combined Immunodeficiency. American Journal Of Clinical Pathology 2016, 145: 251-257. PMID: 26834123, PMCID: PMC4901308, DOI: 10.1093/ajcp/aqv079.Peer-Reviewed Original ResearchConceptsMaternal T-cell engraftmentT-cell engraftmentPeripheral blood leukocytesSevere combined immunodeficiencyHuman leukocyte antigen (HLA) typingPatients' buccal cellsHLA typingBlood leukocytesSequence-specific primersBuccal cellsAntigen typingCombined immunodeficiencyAllogeneic hematopoietic stem cell transplantationPatient's peripheral blood leukocytesHematopoietic stem cell transplantationStem cell transplantationHLA-C locusAccurate HLA typingPatient's CD3Immunologic assessmentSequence-specific oligonucleotidesCell transplantationBlood chimerismT lymphocytesRepeat testing