2023
Allotransplantation and Gene Therapy Equity for Children with Sickle Cell Disease: Distributional Cost-Effectiveness of Allotransplantation Vs Gene Therapy Vs Standard-of-Care in Pediatric Patients with Sickle Cell Disease in the United States
Goshua G, Ito S, Chetlapalli K, Potnis K, Calhoun C, Krishnamurti L, Krumholz H, Pandya A. Allotransplantation and Gene Therapy Equity for Children with Sickle Cell Disease: Distributional Cost-Effectiveness of Allotransplantation Vs Gene Therapy Vs Standard-of-Care in Pediatric Patients with Sickle Cell Disease in the United States. Blood 2023, 142: 490. DOI: 10.1182/blood-2023-191072.Peer-Reviewed Original ResearchSickle cell diseaseIncremental cost-effectiveness ratioDistributional cost-effectiveness analysisPediatric patientsCell diseaseCost-effectiveness analysisDisease severityHealth resource utilization dataPediatric Health Information SystemGene therapyJustifiable treatment optionTransplant-related mortalityVaso-occlusive crisisExpert clinical experienceMarrow Transplant ResearchSubstantial mortality riskVisual analog scaleQuality-adjusted life expectancyConcomitant riskCost-effectiveness ratioResource utilization dataCost-effectiveness frontierHost diseaseMaximum patientsOpioid therapy
2017
Current Healthcare Utilization Patterns and Most Common Reasons for Admission Amongst Patients with Sickle Cell Disease
Calhoun C, Keller M, Olsen M, King A. Current Healthcare Utilization Patterns and Most Common Reasons for Admission Amongst Patients with Sickle Cell Disease. Blood 2017, 130: 866. DOI: 10.1182/blood.v130.suppl_1.866.866.Peer-Reviewed Original ResearchSickle cell diseaseVaso-occlusive crisisSCD patientsState Inpatient DatabasesIndex hospitalizationRespiratory infectionsHealthcare utilizationSCD populationAge groupsAdult careCell diseaseCommon reasonHuman Research Protection OfficeICD-9-CM diagnosis codesICD-9-CM diagnosisUtilization Project State Inpatient DatabasesYoung adult age groupPrimary insurance typeVaso-occlusive episodesAnnual healthcare costsChronic lung diseaseHealthcare utilization patternsHospital resource useYears age groupHigher mortality risk