2004
Leg glucose and protein metabolism during an acute bout of resistance exercise in humans
Durham WJ, Miller SL, Yeckel CW, Chinkes DL, Tipton KD, Rasmussen BB, Wolfe RR. Leg glucose and protein metabolism during an acute bout of resistance exercise in humans. Journal Of Applied Physiology 2004, 97: 1379-1386. PMID: 15194677, DOI: 10.1152/japplphysiol.00635.2003.Peer-Reviewed Original ResearchConceptsLeg blood flowResistance exercisePhenylalanine rateLeg glucoseAcute boutBlood flowLactate releaseProtein breakdownWhole-body protein breakdownLower body resistance exerciseGlucose uptakeLeg glucose uptakeLeg lactate releaseBody resistance exerciseVenous blood samplesMuscle protein synthesisProtein metabolismBody protein breakdownExercise regimenExercise boutLeg pressGlutamate uptakeMuscle biopsyProtein synthesisBlood samples
1998
Exogenous amino acids stimulate net muscle protein synthesis in the elderly.
Volpi E, Ferrando A, Yeckel C, Tipton K, Wolfe R. Exogenous amino acids stimulate net muscle protein synthesis in the elderly. Journal Of Clinical Investigation 1998, 101: 2000-2007. PMID: 9576765, PMCID: PMC508787, DOI: 10.1172/jci939.Peer-Reviewed Original ResearchConceptsMuscle protein synthesisAmino acid infusionFractional synthetic rateAmino acid transportAcid infusionMuscle massNet muscle protein synthesisMuscle protein fractional synthetic rateMuscle protein anabolismAcid transportProtein fractional synthetic rateHealthy elderly individualsIntake of proteinAmino acid kineticsAmino acid deliveryAmino acid availabilityAcid availabilityProtein synthesisIntravenous infusionMuscle biopsyElderly individualsProtein anabolismVastus lateralisPostabsorptive stateAmino acid mixture