Exogenous amino acids stimulate net muscle protein synthesis in the elderly.
Volpi E, Ferrando A, Yeckel C, Tipton K, Wolfe R. Exogenous amino acids stimulate net muscle protein synthesis in the elderly. Journal Of Clinical Investigation 1998, 101: 2000-2007. PMID: 9576765, PMCID: PMC508787, DOI: 10.1172/jci939.Peer-Reviewed Original ResearchMeSH KeywordsAgedAmino AcidsBiological TransportBiopsyCatheters, IndwellingHumansInfusions, IntravenousLegMaleModels, BiologicalMuscle ProteinsMuscle, SkeletalConceptsMuscle protein synthesisAmino acid infusionFractional synthetic rateAmino acid transportAcid infusionMuscle massNet muscle protein synthesisMuscle protein fractional synthetic rateMuscle protein anabolismAcid transportProtein fractional synthetic rateHealthy elderly individualsIntake of proteinAmino acid kineticsAmino acid deliveryAmino acid availabilityAcid availabilityProtein synthesisIntravenous infusionMuscle biopsyElderly individualsProtein anabolismVastus lateralisPostabsorptive stateAmino acid mixture