2023
1541-P: Sympathetic Nervous System Activity in Response to Food Ingestion Is Impacted by Obesity
CHUNG T, DEAJON-JACKSON J, BINI J, SONG H, SANCHEZ RANGEL E, YECKEL C, HWANG J, STACHENFELD N, BELFORT-DEAGUIAR R. 1541-P: Sympathetic Nervous System Activity in Response to Food Ingestion Is Impacted by Obesity. Diabetes 2023, 72 DOI: 10.2337/db23-1541-p.Peer-Reviewed Original ResearchSympathetic nervous system activityMuscle sympathetic nerve activityMixed meal testNormal weightNervous system activityDistribution volume ratioPET-CTHeart rateSympathetic nerve activitySystem activityIngestion of foodMSNA increasesEndogenous NEMeal testNE releaseNerve activityOB subjectsObesity altersKidney diseaseDeltoid muscleLean individualsOB individualsNE transporterObeseFood ingestion
2018
Glycemic Variability from CGM Correlates with Indices of Glucose Metabolism in Healthy Obesity but Not in Type 2 Diabetes
ELSHAFIE A, LAM W, PARIKH L, RANGEL E, SCHMIDT C, HWANG J, YECKEL C, SHERWIN R, BELFORT-DEAGUIAR R. Glycemic Variability from CGM Correlates with Indices of Glucose Metabolism in Healthy Obesity but Not in Type 2 Diabetes. Diabetes 2018, 67 DOI: 10.2337/db18-82-lb.Peer-Reviewed Original ResearchGlucose infusion rateInsulin secretion-sensitivity index-2Beta-cell functionContinuous overlapping net glycemic actionGlucose variabilityContinuous glucose monitorT2D subjectsObese subjectsInsulin levelsGV indicesGlucose metabolismCell functionInsulin sensitivity indexType 2 diabetesGlycemic Risk AssessmentCGM indicesHealthy obesityMannKind CorporationHealthy obeseOB subjectsGlycemic excursionsInsulin resistanceIncremental AUCGlycemic variabilityRegeneron Pharmaceuticals