1991
A Preliminary, Open Study of the Combination of Fluoxetine and Desipramine for Rapid Treatment of Major Depression
Nelson JC, Mazure CM, Bowers MB, Jatlow PI. A Preliminary, Open Study of the Combination of Fluoxetine and Desipramine for Rapid Treatment of Major Depression. JAMA Psychiatry 1991, 48: 303-307. PMID: 2009031, DOI: 10.1001/archpsyc.1991.01810280019002.Peer-Reviewed Original ResearchConceptsMajor depressionMean changeHamilton Depression Rating Scale scoresDepression Rating Scale scoresCombination of fluoxetineDesipramine plasma levelsRating Scale scoresBeta-adrenergic receptorsOpen studyDesipramine levelsPlasma levelsStandardized doseScale scoreDesipramineDesipramine hydrochlorideRapid treatmentPatientsFluoxetineDrugsWeeksDepressionInpatientsTreatmentRecent studiesSame setting
1989
The Yale-Brown Obsessive Compulsive Scale: II. Validity
Goodman WK, Price LH, Rasmussen SA, Mazure C, Delgado P, Heninger GR, Charney DS. The Yale-Brown Obsessive Compulsive Scale: II. Validity. JAMA Psychiatry 1989, 46: 1012-1016. PMID: 2510699, DOI: 10.1001/archpsyc.1989.01810110054008.Peer-Reviewed Original ResearchConceptsObsessive-compulsive disorderYale-Brown Obsessive Compulsive ScaleObsessive Compulsive ScaleYale-Brown scaleScale scoreCompulsive ScaleSecondary depressive symptomsPlacebo-controlled trialCohort of patientsDrug-induced changesObsessive-compulsive disorder symptom severityMeasures of depressionDrug trialsOutcome measuresDisorder symptom severityDepressive symptomsObsessive-compulsive disorder symptomsSymptom severityPatientsBaseline ratingsDisordersDisorder symptomsValid instrumentSymptomsTrials