2012
Mineralizing Enthesopathy Is a Common Feature of Renal Phosphate-Wasting Disorders Attributed to FGF23 and Is Exacerbated by Standard Therapy in Hyp Mice
Karaplis A, Bai X, Falet J, Macica C. Mineralizing Enthesopathy Is a Common Feature of Renal Phosphate-Wasting Disorders Attributed to FGF23 and Is Exacerbated by Standard Therapy in Hyp Mice. Endocrinology 2012, 153: 5906-5917. PMID: 23038738, PMCID: PMC3512070, DOI: 10.1210/en.2012-1551.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsExtracellular Matrix ProteinsFamilial Hypophosphatemic RicketsFemaleFibroblast Growth Factor-23Fibroblast Growth FactorsGenetic Diseases, X-LinkedImmunohistochemistryKidneyMaleMiceMice, Inbred C57BLMice, TransgenicModels, GeneticMutationPedigreePhosphatesPhosphoproteinsRheumatic DiseasesTransgenesUp-RegulationConceptsPhosphate-wasting disordersStandard therapyFGF23 levelsElevated fibroblast growth factor 23Hyp miceRenal phosphate-wasting disordersFibroblast growth factor 23High FGF23 levelsGrowth factor 23Elevated FGF23 levelsAction of FGF23Dentin matrix acidic phosphoprotein 1Phosphate wasting disorderAutosomal recessive hypophosphatemic ricketsRecessive hypophosphatemic ricketsLigament insertion sitesChildhood managementOral phosphateFactor 23Achilles insertionDisease morbidityPotential morbidityBone spursUntoward effectsMurine model
1991
Localization of endothelin-like immunoreactivity in rat kidneys
Wilkes B, Susin M, Mento P, Macica C, Girardi E, Boss E, Nord E. Localization of endothelin-like immunoreactivity in rat kidneys. American Journal Of Physiology 1991, 260: f913-f920. PMID: 2058711, DOI: 10.1152/ajprenal.1991.260.6.f913.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsEndothelinsGlomerular MesangiumImmunoenzyme TechniquesImmunohistochemistryKidneyKidney TubulesMaleRatsRats, Inbred StrainsConceptsEndothelin-like immunoreactivityVasa rectaeEndothelin-1Renal papillaRat kidneyProximal tubule brush borderDistal nephron segmentsTubule brush borderNormal rat kidneyGlomerular immunostainingArcuate arteriesPeritubular capillariesRenal cortexRenal tissueImmunoperoxidase techniqueParacrine actionIntense immunostainingCytoplasmic immunostainingDuct epitheliumImmunostaining densityRenal medullaBig endothelinNephron segmentsImmunoreactivityImmunostaining