Glomerular endothelin receptors during initiation and maintenance of ischemic acute renal failure in rats
Wilkes B, Pearl A, Mento P, Maita M, Macica C, Girardi E. Glomerular endothelin receptors during initiation and maintenance of ischemic acute renal failure in rats. American Journal Of Physiology 1991, 260: f110-f118. PMID: 1847009, DOI: 10.1152/ajprenal.1991.260.1.f110.Peer-Reviewed Original ResearchConceptsIschemic acute renal failureAcute renal failureRenal blood flowGlomerular filtration rateET receptorsRenal failureEndothelin receptorsET infusionElevated ET levelsLeft renal arteryMean arterial pressureNormal Sprague-Dawley ratsSprague-Dawley ratsReceptor sitesRenal hemodynamicsArterial pressureContralateral kidneyRenal arteryFiltration rateReceptor numberBlood flowET levelsRatsET bindingAdditional studies