Featured Publications
Antiplatelet regimens following carotid artery revascularization
Lee M, Ahmed ZV, Huang J, Brice A, Arham A, Castro-Dominguez Y, Aboian E, Nagpal S, Smolderen KG, Mena-Hurtado C. Antiplatelet regimens following carotid artery revascularization. American Heart Journal 2022, 253: 48-52. PMID: 35863439, DOI: 10.1016/j.ahj.2022.07.004.Peer-Reviewed Original ResearchConceptsDual antiplatelet therapySingle antiplatelet therapyCarotid artery stentingCarotid endarterectomyAntiplatelet therapyReal-world clinical practiceCarotid artery revascularizationLow adherence ratesArtery revascularizationArtery stentingAdherence ratesClinical practicePatientsTherapyEngland dataHigh percentageRevascularizationAntiplateletEndarterectomyStenting
2020
Intravascular Lithotripsy for Treatment of Calcified Lesions During Carotid Artery Stenting
Giannopoulos S, Speziale F, Vadalà G, Soukas P, Kuhn BA, Stoltz CL, Foteh MI, Mena-Hurtado C, Armstrong EJ. Intravascular Lithotripsy for Treatment of Calcified Lesions During Carotid Artery Stenting. Journal Of Endovascular Therapy 2020, 28: 93-99. PMID: 32869718, DOI: 10.1177/1526602820954244.Peer-Reviewed Original ResearchConceptsCarotid artery lesionsIntravascular lithotripsyArtery lesionsCarotid duplex ultrasound examinationAortic arch manipulationDual antiplatelet therapyCarotid artery stentingEmbolic protection devicesDuplex ultrasound examinationCarotid artery stenosisLong-term safetyArch manipulationBaseline stenosisAntiplatelet therapyAsymptomatic patientsSignificant restenosisIschemic strokeISR lesionsRisk patientsStent restenosesTransfemoral accessAdverse eventsArtery stentingArtery stenosisSymptomatic bradycardia
2016
Carotid artery stenting versus carotid endarterectomy
Nanna MG, Gomes P, Njoh RF, Ward C, Attaran RR, Mena C. Carotid artery stenting versus carotid endarterectomy. Postgraduate Medical Journal 2016, 92: 532-539. PMID: 27317752, DOI: 10.1136/postgradmedj-2015-133689.Peer-Reviewed Original ResearchMeSH KeywordsAsymptomatic DiseasesCarotid StenosisEndarterectomy, CarotidEndovascular ProceduresHumansStentsStrokeConceptsCarotid endarterectomyCarotid artery stentingCarotid artery stenosisArtery stentingMedical therapyArtery stenosisCarotid stenosisTreatment optionsSurgical techniqueTreatment strategiesCarotid arteryMajor causeEndarterectomyStenosisStrokeMorbidityStentingArterySignificant contributorOptionsTherapyMortalityTrialsCarotid stenting versus endarterectomy for the treatment of carotid artery stenosis: Contemporary results from a large single center study
Meller SM, Al‐Damluji M, Gutierrez A, Stilp E, Mena‐Hurtado C. Carotid stenting versus endarterectomy for the treatment of carotid artery stenosis: Contemporary results from a large single center study. Catheterization And Cardiovascular Interventions 2016, 88: 822-830. PMID: 27219323, DOI: 10.1002/ccd.26593.Peer-Reviewed Original ResearchConceptsBaseline medical comorbiditiesMedical comorbiditiesComposite endpointMyocardial infarctionSymptom statusCarotid revascularizationCarotid endarterectomy (CEA) versus carotid arteryPrimary end pointCause of strokeOccurrence of strokeEmbolic protection devicesCarotid artery stenosisMultivariate regression analysisHigh ratePeriprocedural deathPeriprocedural strokeComplication rateArtery stenosisCarotid stenosisPatient populationCarotid arteryComorbiditiesEnd pointStrokePatients
2015
Readmissions After Carotid Artery Revascularization in the Medicare Population
Al-Damluji MS, Dharmarajan K, Zhang W, Geary LL, Stilp E, Dardik A, Mena-Hurtado C, Curtis JP. Readmissions After Carotid Artery Revascularization in the Medicare Population. Journal Of The American College Of Cardiology 2015, 65: 1398-1408. PMID: 25857904, PMCID: PMC4403264, DOI: 10.1016/j.jacc.2015.01.048.Peer-Reviewed Original ResearchConceptsRisk-standardized readmission ratesCarotid artery stentingHospital risk-standardized readmission ratesCarotid revascularizationCarotid endarterectomyReadmission ratesHospital variationReadmission riskService administrative claims dataKaplan-Meier survival curvesLogistic regressionCarotid artery revascularizationPrior clinical researchAcute care hospitalizationDays of dischargeHospital-level variationSevere carotid stenosisCause hospital readmissionAdministrative claims dataMixed-effects logistic regressionChoice of procedureArtery revascularizationIschemic strokeArtery stentingHospital readmission
2014
Management of Symptomatic Carotid Disease in 2014
Litsky J, Stilp E, Njoh R, Mena-Hurtado C. Management of Symptomatic Carotid Disease in 2014. Current Cardiology Reports 2014, 16: 462. PMID: 24464307, DOI: 10.1007/s11886-013-0462-3.Peer-Reviewed Original ResearchConceptsSymptomatic carotid stenosisCarotid artery stentingCarotid endarterectomyCarotid stenosisMedical therapyHigh-grade symptomatic carotid stenosisExtracranial carotid artery stenosisPreventive medical therapyClass I recommendationSymptomatic carotid diseaseCarotid artery stenosisCause of deathRetinal symptomsStroke preventionArtery stentingI recommendationLandmark trialsPerioperative eventsArtery stenosisCarotid diseaseSymptomatic lesionsNoninvasive evaluationStenosisTherapyModern management
2013
An evidence‐based review of the impact of periprocedural myocardial infarction in carotid revascularization
Stilp E, Baird C, Gray WA, Schneider PA, Simonton CA, Verta P, Mena‐Hurtado C. An evidence‐based review of the impact of periprocedural myocardial infarction in carotid revascularization. Catheterization And Cardiovascular Interventions 2013, 82: 709-714. PMID: 23765902, DOI: 10.1002/ccd.25056.Peer-Reviewed Original ResearchConceptsPeriprocedural myocardial infarctionCarotid endarterectomyRevascularization strategyCarotid revascularizationMyocardial infarctionCarotid arteryIncidence of PMIAsymptomatic atherosclerotic stenosisCarotid revascularization strategiesPatient symptom statusLong-term morbidityCarotid artery stenosisExtracranial carotid arteriesEvidence-based reviewAsymptomatic patientsRevascularization TrialLandmark trialsMedical therapyArtery stenosisRandomized comparisonAtherosclerotic stenosisSymptom statusInvasive optionBiomarker assessmentRevascularizationCarotid Revascularization: A Systematic Review of the Evidence
AL‐DAMLUJI M, NAGPAL S, STILP E, REMETZ M, MENA C. Carotid Revascularization: A Systematic Review of the Evidence. Journal Of Interventional Cardiology 2013, 26: 399-410. PMID: 23844747, DOI: 10.1111/joic.12037.Peer-Reviewed Original ResearchConceptsCarotid artery stentingProspective clinical trialsHigh surgical risk patientsSurgical risk patientsEmbolic protection devicesCarotid endarterectomyClinical trialsRisk patientsMyocardial infarctionIncidence rateSafety of CASEffective stroke prevention strategiesHigh surgical risk candidatesLong-term outcome ratesObjective performance criteriaTrials (RCTs) comparing outcomesHigh surgical riskStroke prevention strategiesEvidence-based reviewPatient selection strategiesLong-term effectivenessArtery stentingPeriprocedural safetySurgical riskComparing outcomes