170 Efficacy and Safety of Dasotraline in Adults with Binge-Eating Disorder: A Randomized, Double-blind, Fixed-dose Trial
Tsai J, Navia B, McElroy S, Hudson J, Grilo C, Goldman R, Deng L, Kent J, Loebel A. 170 Efficacy and Safety of Dasotraline in Adults with Binge-Eating Disorder: A Randomized, Double-blind, Fixed-dose Trial. CNS Spectrums 2020, 25: 308-309. DOI: 10.1017/s1092852920000863.Peer-Reviewed Original ResearchBinge-eating disorderEfficacy endpointWeek 12Dopamine/norepinephrine reuptake inhibitorFlexible-dose studySafety of dasotralineDouble-blind treatmentFixed-dose studyPrimary efficacy endpointProportion of patientsSecondary efficacy endpointsClinical Global ImpressionNorepinephrine reuptake inhibitorsWeeks of treatmentTreatment of patientsCompulsive Scale ModifiedBinge-eating episodesDSM-5 criteriaYale-Brown ObsessiveITT populationReuptake inhibitorsGlobal ImpressionDose studySignificant efficacySeverity Scale