New potential ligand-receptor axis involved in tissue repair as therapeutic targets in progressive multiple sclerosis.
Carrera Silva E, Correale J, Rothlin C, Ortiz Wilczyñski J. New potential ligand-receptor axis involved in tissue repair as therapeutic targets in progressive multiple sclerosis. Journal Of Pharmacology And Experimental Therapeutics 2024, 100029. PMID: 39379148, DOI: 10.1124/jpet.124.002254.Peer-Reviewed Original ResearchProgressive multiple sclerosisLigand-receptor axisNeuroprotective therapeutic strategiesMultiple sclerosisTissue repairTherapeutic strategiesRefractory to current treatmentsIncreasing preclinical evidenceStages of multiple sclerosisEarly stages of multiple sclerosisAnti-inflammatoryPromote tissue repairTissue repair processPreclinical evidenceTherapeutic optionsReceptor axisReceptor/ligand pairsCurrent treatmentPathogenic mechanismsMS diseaseBenefit patientsTherapeutic interventionsTherapeutic targetSignaling axisEra of omics