2022
Differences in the Delivery of Medications for Opioid use Disorder during Hospitalization by Racial Categories: A Retrospective Cohort Analysis;
Priest K, King C, Englander H, Lovejoy T, McCarty D. Differences in the Delivery of Medications for Opioid use Disorder during Hospitalization by Racial Categories: A Retrospective Cohort Analysis;. Substance Abuse 2022, 43: 1251-1259. PMID: 35670778, PMCID: PMC10292919, DOI: 10.1080/08897077.2022.2074601.Peer-Reviewed Original ResearchConceptsOpioid use disorderVeterans Health AdministrationWhite patientsUse disordersMOUD deliveryBlack patientsDelivery of buprenorphineType of MOUDRetrospective cohort analysisAcute care hospitalsCOVID-19 pandemic continuesDelivery of medicationsOutpatient clinical environmentLogistic regression modelsMOUD accessAddiction treatment systemCare hospitalStudy cohortSurgical hospitalizationMean ageCohort analysisHospitalizationMOUDPatientsBuprenorphine
2021
Expert Panel Consensus on Management of Advanced Cancer–Related Pain in Individuals With Opioid Use Disorder
Merlin JS, Khodyakov D, Arnold R, Bulls HW, Dao E, Kapo J, King C, Meier D, Paice J, Ritchie C, Liebschutz JM. Expert Panel Consensus on Management of Advanced Cancer–Related Pain in Individuals With Opioid Use Disorder. JAMA Network Open 2021, 4: e2139968. PMID: 34962565, DOI: 10.1001/jamanetworkopen.2021.39968.Peer-Reviewed Original ResearchConceptsOpioid use disorderFull agonist opioidsAdvanced cancerUncertain appropriatenessCancer painPalliative careUse disordersCancer pain managementAppropriateness of managementExpert panel consensusConsensus-based guidanceImportant comorbidityOpioid medicationsPain managementMethadone clinicsPainPatientsPanel consensusPrognosisCancerMethadoneDelphi processExpert panelMonthsOpioidsAssociations between fentanyl use and initiation, persistence, and retention on medications for opioid use disorder among people living with uncontrolled HIV disease
Cook R, Torralva R, King C, Lum P, Tookes H, Foot C, Vergara-Rodriguez P, Rodriguez A, Fanucchi L, Lucas G, Waddell E, Korthuis P. Associations between fentanyl use and initiation, persistence, and retention on medications for opioid use disorder among people living with uncontrolled HIV disease. Drug And Alcohol Dependence 2021, 228: 109077. PMID: 34600253, PMCID: PMC8595584, DOI: 10.1016/j.drugalcdep.2021.109077.Peer-Reviewed Original ResearchConceptsUncontrolled HIV diseaseFentanyl useOpioid use disorderXR-NTXHIV diseaseUse disordersTreatment of OUDUncontrolled HIV infectionExtended-release naltrexoneHIV viral suppressionUrine drug screeningExposure of interestMultisite clinical trialPercent of participantsMethadone administrationMOUD initiationMOUD retentionViral suppressionBuprenorphine prescriptionsHIV infectionClinical trialsWeek 20First injectionAdministrationMOUDDesigning and validating a Markov model for hospital-based addiction consult service impact on 12-month drug and non-drug related mortality
King C, Englander H, Korthuis P, Barocas J, McConnell K, Morris C, Cook R. Designing and validating a Markov model for hospital-based addiction consult service impact on 12-month drug and non-drug related mortality. PLOS ONE 2021, 16: e0256793. PMID: 34506517, PMCID: PMC8432751, DOI: 10.1371/journal.pone.0256793.Peer-Reviewed Original ResearchMeSH KeywordsAdultCohort StudiesFemaleHospitalizationHumansMaleMarkov ChainsMiddle AgedOpioid-Related DisordersOregonConceptsAddiction consult serviceOpioid use disorderDrug-related deathsHospitalized patientsOUD careRelated mortalityPercent of patientsNon-drug related deathTrajectory of careSubstance use treatmentLogistic regression modelsACS careOUD treatmentPatient survivalRelated deathsSUD careConsult serviceMedicaid dataPatientsUse disordersMortalityUse treatmentCareBayesian logistic regression modelDeathUnderstanding the impact of the SARS-COV-2 pandemic on hospitalized patients with substance use disorder
King C, Vega T, Button D, Nicolaidis C, Gregg J, Englander H. Understanding the impact of the SARS-COV-2 pandemic on hospitalized patients with substance use disorder. PLOS ONE 2021, 16: e0247951. PMID: 33635926, PMCID: PMC7909702, DOI: 10.1371/journal.pone.0247951.Peer-Reviewed Original ResearchConceptsSubstance use disordersSARS-CoV-2 pandemicHospitalized patientsUse disordersHospital policy changesAcademic medical centerExperiences of healthcareAcute illnessOutpatient careMedical CenterPatientsHospitalCommunity resourcesDisordersPandemicQualitative studyThematic analysisSemi-structured interviewsSurvival adaptationHospitalizationIllnessMain themesCareHIV clinic-based buprenorphine plus naloxone versus referral for methadone maintenance therapy for treatment of opioid use disorder in HIV clinics in Vietnam (BRAVO): an open-label, randomised, non-inferiority trial
Korthuis P, King C, Cook R, Khuyen T, Kunkel L, Bart G, Nguyen T, Thuy D, Bielavitz S, Nguyen D, Tam N, Giang L. HIV clinic-based buprenorphine plus naloxone versus referral for methadone maintenance therapy for treatment of opioid use disorder in HIV clinics in Vietnam (BRAVO): an open-label, randomised, non-inferiority trial. The Lancet HIV 2021, 8: e67-e76. PMID: 33539760, PMCID: PMC8082651, DOI: 10.1016/s2352-3018(20)30302-7.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnti-HIV AgentsAntiretroviral Therapy, Highly ActiveBuprenorphineCD4 Lymphocyte CountDrug Therapy, CombinationFemaleHIV InfectionsHumansMaleMethadoneMiddle AgedNaloxoneNarcotic AntagonistsNarcoticsOpiate Substitution TreatmentOpioid-Related DisordersPatient ComplianceRandom AllocationRNA, ViralTreatment OutcomeVietnamViral LoadConceptsMethadone maintenance therapyOpioid use disorderHIV viral suppressionMaintenance therapySerious adverse eventsViral suppressionAdverse eventsNon-inferiority trialUse disordersHIV clinicNaloxone treatmentComputer-generated random number sequenceOpioid use disorder medicationsTreatment-emergent adverse eventsHIV clinic visitsQuarterly study visitsBuprenorphine adherenceCD4 countHIV careClinic visitsBuprenorphine treatmentHIV outcomesMiddle-income countriesPrimary outcomeMean age
2020
Evaluating new paralysis, mortality, and readmission among subgroups of patients with spinal epidural abscess: A latent class analysis
Brown P, Phillipi G, King C, Tanski M, Sullivan P. Evaluating new paralysis, mortality, and readmission among subgroups of patients with spinal epidural abscess: A latent class analysis. PLOS ONE 2020, 15: e0238853. PMID: 32915861, PMCID: PMC7485888, DOI: 10.1371/journal.pone.0238853.Peer-Reviewed Original ResearchConceptsSpinal epidural abscessSubgroup of patientsClinical outcomesPatient populationGroup 2Group 1Longer hospital courseSubstance use disorder diagnosisLatent class analysisSubstance use disordersChi-square testCharacteristics of subgroupsHospital mortalityEpidural abscessHospital courseMedical comorbiditiesSignificant morbidityVascular accessRisk factorsClinical subgroupsHealth centersSupport patientsHigh riskPatientsSubsequent mortalityCommunity-derived recommendations for healthcare systems and medical students to support people who are houseless in Portland, Oregon: a mixed-methods study
King C, Fisher C, Johnson J, Chun A, Bangsberg D, Carder P. Community-derived recommendations for healthcare systems and medical students to support people who are houseless in Portland, Oregon: a mixed-methods study. BMC Public Health 2020, 20: 1337. PMID: 32878612, PMCID: PMC7466795, DOI: 10.1186/s12889-020-09444-4.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttitude to HealthBehavior, AddictiveDelivery of Health CareFemaleHealth Services Needs and DemandHousingHumansIll-Housed PersonsMaleMental DisordersMental HealthMiddle AgedOregonPatient AdvocacyPopulation HealthProfessional-Patient RelationsQualitative ResearchSocial ChangeSocial StigmaSocial SupportStudents, MedicalSubstance-Related DisordersSurveys and QuestionnairesConceptsCommunity-based organizationsQualitative interview guideSelf-identified needsMixed-methods surveyInstitutional levelSemi-structured qualitative interview guideHouselessMixed-methods studyQualitative dataDisproportionate disparitiesThematic analysisInstitutionsQualitative themesInterview guideHouselessnessTraining institutionsPeopleCare experiencesHealth of peopleHealthcare systemTime of interviewMental health conditionsSubstance use disordersCommunityStigmaCommunity Outreach for Navajo People Living with Diabetes: Who Benefits Most?
Trevisi L, Orav J, Atwood S, Brown C, Curley C, King C, Muskett O, Sehn H, Nelson A, Begay M, Shin S. Community Outreach for Navajo People Living with Diabetes: Who Benefits Most? Preventing Chronic Disease 2020, 17: e68. PMID: 32701432, PMCID: PMC7380292, DOI: 10.5888/pcd17.200068.Peer-Reviewed Original ResearchConceptsPrimary care providersBaseline HbACommunity Health RepresentativesMental health conditionsCare providersCOPE patientsHealth conditionsGlycated hemoglobin APrimary care physiciansRoutine health recordsPatient empowerment interventionCommunity outreachDe-identified dataPreferred languageCare physiciansCOPE interventionPatientsHealth representativesDiabetesHealth recordsHemoglobin AHbALinear mixed modelsInterventionEmpowerment interventionHIV care continuum characteristics among people with opioid use disorder and HIV in Vietnam: baseline results from the BRAVO study
King C, Giang L, Bart G, Kunkel L, Korthuis P. HIV care continuum characteristics among people with opioid use disorder and HIV in Vietnam: baseline results from the BRAVO study. BMC Public Health 2020, 20: 421. PMID: 32228522, PMCID: PMC7106608, DOI: 10.1186/s12889-020-08538-3.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalgesics, OpioidAnti-Retroviral AgentsBuprenorphineContinuity of Patient CareFemaleHIV InfectionsHumansLogistic ModelsMaleMethadoneMiddle AgedOpiate Substitution TreatmentOpioid-Related DisordersPatient Acceptance of Health CareRandomized Controlled Trials as TopicVietnamViral LoadConceptsHIV viral suppressionOpioid use disorderReceipt of ARTAntiretroviral therapyViral suppressionUse disordersART statusParticipant characteristicsHIV care continuumBaseline participant characteristicsGreater depression symptomsLogistic regression modelsART initiationHIV peopleHIV diagnosisPatient characteristicsClinical trialsCare continuumDepression symptomsStudy participantsCurrent prescriptionDisordersBaselineRegression modelsPrimary objectiveTime-to-completed-imaging, survival and function in patients with spinal epidural abscess: Description of a series of 34 patients, 2015–2018
King C, Fisher C, Brown P, Priest K, Tanski M, Sullivan P. Time-to-completed-imaging, survival and function in patients with spinal epidural abscess: Description of a series of 34 patients, 2015–2018. BMC Health Services Research 2020, 20: 119. PMID: 32059715, PMCID: PMC7023770, DOI: 10.1186/s12913-020-4973-5.Peer-Reviewed Original ResearchConceptsIntravenous drug useDrug useEpidural abscessEmergency departmentRisk factorsMethodsThis retrospective cohort studySingle academic medical centerMean timeRetrospective cohort studySpinal epidural abscessLife-threatening infectionsAcademic medical centerMulti-center approachShorter mean timeCohort studyNeurologic symptomsBack painClassic triadSignificant morbiditySurgical interventionSingle hospitalQuality improvement workMedical CenterPrompt identificationPatients
2019
Integrating community health representatives with health care systems: clinical outcomes among individuals with diabetes in Navajo Nation
Trevisi L, Orav J, Atwood S, Brown C, Curley C, King C, Muskett O, Sehn H, Nelson K, Begay M, Shin S. Integrating community health representatives with health care systems: clinical outcomes among individuals with diabetes in Navajo Nation. International Journal For Equity In Health 2019, 18: 183. PMID: 31771603, PMCID: PMC6880375, DOI: 10.1186/s12939-019-1097-9.Peer-Reviewed Original ResearchConceptsCommunity Health RepresentativesClinical outcomesHealth representativesSystolic blood pressureBody mass indexRoutine clinical dataLow-density lipoproteinIntegrated care teamsPatient empowerment interventionHealth care systemHealth service information systemCOPE groupCOPE patientsClinical characteristicsBlood pressureDiabetes mellitusMass indexCare teamClinical dataLipid levelsHome visitsCOPE interventionNavajo populationPatientsClinical sites
2018
Glycemic control and healthcare utilization following pregnancy among women with pre-existing diabetes in Navajo Nation
Ho J, Bachman-Carter K, Thorkelson S, Anderson K, Jaggi J, Brown C, Nelson A, Curley C, King C, Atwood S, Shin S. Glycemic control and healthcare utilization following pregnancy among women with pre-existing diabetes in Navajo Nation. BMC Health Services Research 2018, 18: 629. PMID: 30097012, PMCID: PMC6086058, DOI: 10.1186/s12913-018-3434-x.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultArizonaBlood GlucoseDiabetes Mellitus, Type 2Facilities and Services UtilizationFemaleGlycated HemoglobinHealth Services, IndigenousHumansIndians, North AmericanLogistic ModelsMiddle AgedNew MexicoPatient Acceptance of Health CarePostnatal CarePregnancyPregnancy in DiabeticsPrenatal CareRetrospective StudiesUnited StatesUtahYoung AdultConceptsPre-existing diabetesGlycemic controlIndian Health Service HospitalSpecialized prenatal careRetrospective chart reviewPatient-level predictorsPrimary care providersImmediate postpartum periodResultsOne hundred twentyType 2 diabetesContinuity of healthcareTribal Health SystemBaseline HbA1cChart reviewPrimary outcomeHealthcare utilizationPrenatal carePostpartum periodPregnancy periodHundred twentyService hospitalsCare providersGeneral populationOnly covariatePregnancyIdentifying risk factors for 30-day readmission events among American Indian patients with diabetes in the Four Corners region of the southwest from 2009 to 2016
King C, Atwood S, Lozada M, Nelson A, Brown C, Sabo S, Curley C, Muskett O, Orav E, Shin S. Identifying risk factors for 30-day readmission events among American Indian patients with diabetes in the Four Corners region of the southwest from 2009 to 2016. PLOS ONE 2018, 13: e0195476. PMID: 30070989, PMCID: PMC6071952, DOI: 10.1371/journal.pone.0195476.Peer-Reviewed Original Research
2017
Primary care and survival among American Indian patients with diabetes in the Southwest United States: Evaluation of a cohort study at Gallup Indian Medical Center, 2009–2016
King C, Atwood S, Brown C, Nelson A, Lozada M, Wei J, Merino M, Curley C, Muskett O, Sabo S, Gampa V, Orav J, Shin S. Primary care and survival among American Indian patients with diabetes in the Southwest United States: Evaluation of a cohort study at Gallup Indian Medical Center, 2009–2016. Primary Care Diabetes 2017, 12: 212-217. PMID: 29229284, DOI: 10.1016/j.pcd.2017.11.003.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAge FactorsAgedAged, 80 and overCause of DeathChildCohort StudiesDatabases, FactualDiabetes MellitusFemaleHospitalizationHumansIndians, North AmericanKaplan-Meier EstimateMaleMiddle AgedPrimary Health CareProportional Hazards ModelsRetrospective StudiesRisk AssessmentSex FactorsSouthwestern United StatesStatistics, NonparametricSurvival AnalysisYoung AdultConceptsPrimary care providersLog-rank testAmerican Indian patientsCare providersIndian patientsCox proportional hazards analysisStudy periodProportional hazards analysisMedian survival timeCause mortalityCohort studyOverall survivalImproved survivalFirst admissionUnadjusted analysesPrimary careMedical CenterSurvival timePatientsAdmissionDiabetesSurvivalHealthcare deliverySignificant differencesHazard analysis