Simulating the impact of Addiction Consult Services in the context of drug supply contamination, hospitalizations, and drug-related mortality
King C, Cook R, Wheelock H, Korthuis P, Leahy J, Goff A, Morris C, Englander H. Simulating the impact of Addiction Consult Services in the context of drug supply contamination, hospitalizations, and drug-related mortality. International Journal Of Drug Policy 2021, 100: 103525. PMID: 34837879, PMCID: PMC8810590, DOI: 10.1016/j.drugpo.2021.103525.Peer-Reviewed Original ResearchConceptsAddiction consult serviceOpioid use disorderDrug-related deathsConsult serviceHospital dischargeCare systemDrug-related causesOpioid-related deathsDrug supplyRisk of overdoseDrug-related mortalityOpioid overdose deathsHarm reduction interventionsAdult patientsOUD patientsHospital admissionOpioid overdosesEffective treatmentOverdose deathsSimulated cohortPatientsUse disordersReduction interventionsHospitalizationDeathAssociations between fentanyl use and initiation, persistence, and retention on medications for opioid use disorder among people living with uncontrolled HIV disease
Cook R, Torralva R, King C, Lum P, Tookes H, Foot C, Vergara-Rodriguez P, Rodriguez A, Fanucchi L, Lucas G, Waddell E, Korthuis P. Associations between fentanyl use and initiation, persistence, and retention on medications for opioid use disorder among people living with uncontrolled HIV disease. Drug And Alcohol Dependence 2021, 228: 109077. PMID: 34600253, PMCID: PMC8595584, DOI: 10.1016/j.drugalcdep.2021.109077.Peer-Reviewed Original ResearchConceptsUncontrolled HIV diseaseFentanyl useOpioid use disorderXR-NTXHIV diseaseUse disordersTreatment of OUDUncontrolled HIV infectionExtended-release naltrexoneHIV viral suppressionUrine drug screeningExposure of interestMultisite clinical trialPercent of participantsMethadone administrationMOUD initiationMOUD retentionViral suppressionBuprenorphine prescriptionsHIV infectionClinical trialsWeek 20First injectionAdministrationMOUD