2016
Executive Dysfunction Predicts Treatment Response to Neuroplasticity-Based Computerized Cognitive Remediation (nCCR-GD) in Elderly Patients with Major Depression
Morimoto SS, Gunning FM, Wexler BE, Hu W, Ilieva I, Liu J, Nitis J, Alexopoulos GS. Executive Dysfunction Predicts Treatment Response to Neuroplasticity-Based Computerized Cognitive Remediation (nCCR-GD) in Elderly Patients with Major Depression. American Journal Of Geriatric Psychiatry 2016, 24: 816-820. PMID: 27591163, PMCID: PMC5873289, DOI: 10.1016/j.jagp.2016.06.010.Peer-Reviewed Original ResearchConceptsExecutive dysfunctionCognitive remediation interventionsComputerized cognitive remediationPoor treatment responseFavorable treatment responseTreatment responseCognitive remediationRemediation interventionsMajor depressionNeuropsychological performanceElderly patientsOlder adultsLate-life depressionMontgomery-Asberg Depression Rating Scale scoreTreatment-resistant major depressionDepression Rating Scale scoresRating Scale scoresDepressionAntidepressant treatmentTreatment trialsScale scorePatientsBaselineGreater reductionDysfunction
1992
The Outpatient Treatment of Depression
WEXLER B, CICCHETTI D. The Outpatient Treatment of Depression. The Journal Of Nervous And Mental Disease 1992, 180: 277-286. PMID: 1533868, DOI: 10.1097/00005053-199205000-00001.Peer-Reviewed Original ResearchConceptsTreatment failure rateTreatment success rateTreatment dropout ratesInitial treatmentRoutine treatmentOutpatient treatmentEffective treatmentDepressed outpatientsSide effectsClinical practiceCombined treatmentRoutine useIndividual psychotherapyMultiple studiesSuccess rateTreatmentPharmacotherapyModest advantageFailure rateDropout ratePsychotherapyUnnecessary costsPatientsOutpatients