2012
Empathy in electrodermal responsive and nonresponsive patients with schizophrenia
Ikezawa S, Corbera S, Liu J, Wexler BE. Empathy in electrodermal responsive and nonresponsive patients with schizophrenia. Schizophrenia Research 2012, 142: 71-76. PMID: 23058162, PMCID: PMC3502678, DOI: 10.1016/j.schres.2012.09.011.Peer-Reviewed Original ResearchMeSH KeywordsAdultAnalysis of VarianceAntipsychotic AgentsChlorpromazineElectroencephalographyEmpathyEvoked PotentialsFemaleGalvanic Skin ResponseHumansMaleMiddle AgedNeuropsychological TestsPersonality TestsPsychiatric Status Rating ScalesPsychotic DisordersRecognition, PsychologySchizophreniaSchizophrenic PsychologySocial BehaviorConceptsSkin conductance responsesEvent Related PotentialsSocial cognitionEmotion-evoking stimuliHealthy controlsPictures of peopleAssessment of symptomsERP responsesPersonal distressConductance responsesRelated potentialsNonresponsive patientsSchizophrenia patientsSCR frequencyCognitionPatientsSocial functionSocial integrationPotential markerSchizophreniaDistressPainPrognosisSubgroupsSymptoms
2010
Predictors of Participation in Community Outpatient Psychosocial Rehabilitation in Schizophrenia
Kurtz MM, Rose J, Wexler BE. Predictors of Participation in Community Outpatient Psychosocial Rehabilitation in Schizophrenia. Community Mental Health Journal 2010, 47: 622-627. PMID: 20676766, PMCID: PMC3046324, DOI: 10.1007/s10597-010-9343-z.Peer-Reviewed Original ResearchMeSH KeywordsAdultAmbulatory CareConnecticutForecastingHumansLogistic ModelsMotivationPatientsPsychotic DisordersRehabilitation CentersSchizophreniaYoung AdultConceptsLower verbal fluency scoresVerbal fluency scoresSchizoaffective disorderPsychosocial rehabilitation programsVerbal learningVerbal abilityNeurocognitive factorsVisual vigilanceVerbal fluencyFluency scoresNeurocognitive assessmentDSM-IV schizophreniaSymptom measuresPsychosocial rehabilitationPredictors of participationDemographic variablesSchizophreniaFinal multivariate modelRehabilitation programGreater likelihoodRace/ethnicityStudy entryFluencyDisordersMeasures
2008
Neurocognitive enhancement therapy with vocational services: Work outcomes at two-year follow-up
Bell MD, Zito W, Greig T, Wexler BE. Neurocognitive enhancement therapy with vocational services: Work outcomes at two-year follow-up. Schizophrenia Research 2008, 105: 18-29. PMID: 18715755, DOI: 10.1016/j.schres.2008.06.026.Peer-Reviewed Original ResearchMeSH KeywordsAdultCognition DisordersCognitive Behavioral TherapyCombined Modality TherapyEmploymentEmployment, SupportedFemaleFollow-Up StudiesHumansMaleNeuropsychological TestsOccupational TherapyPsychiatric Status Rating ScalesPsychotherapy, GroupPsychotic DisordersRehabilitation, VocationalSchizophreniaSchizophrenic PsychologyTreatment OutcomeVocational EducationConceptsNeurocognitive enhancement therapyEnhancement therapyComputer-based cognitive trainingCommunity-based vocational servicesWeekly support groupsCognitive remediationCognitive trainingExecutive functionWork outcomesRemediation programVocational outcomesCommunity mental health centerMental health centersCognitive impairmentSixth quarterVocational servicesNet trainingTherapy outcomeSupport groupsCompetitive employmentSchizophreniaRehabilitation methodsSchizoaffective patientsEmployment programsTrainingSymptoms versus neurocognition as predictors of change in life skills in schizophrenia after outpatient rehabilitation
Kurtz MM, Wexler BE, Fujimoto M, Shagan DS, Seltzer JC. Symptoms versus neurocognition as predictors of change in life skills in schizophrenia after outpatient rehabilitation. Schizophrenia Research 2008, 102: 303-311. PMID: 18495433, PMCID: PMC2519168, DOI: 10.1016/j.schres.2008.03.023.Peer-Reviewed Original ResearchMeSH KeywordsActivities of Daily LivingAdultAmbulatory CareCognition DisordersCognitive Behavioral TherapyFemaleHumansLongitudinal StudiesMaleMiddle AgedNeuropsychological TestsPsychiatric Status Rating ScalesPsychotic DisordersSchizophreniaSchizophrenic PsychologyTherapy, Computer-AssistedVerbal LearningConceptsEveryday life skillsPerformance-based measuresLife skillsVerbal learningVerbal abilityCognitive rehabilitation interventionLongitudinal studyPredictors of changeMeasures of symptomsCognitive interventionsVisual vigilanceSustained vigilanceProcessing speedNeurocognitive deficitsNeurocognitive functionNegative symptomsBody of literatureNeurocognitionSkillsRehabilitation interventionsSchizoaffective disorderOutpatient rehabilitationCurrent studySchizophreniaRehabilitation strategies
2007
Improved cognitive function in schizophrenia after one year of cognitive training and vocational services
Greig TC, Zito W, Wexler BE, Fiszdon J, Bell MD. Improved cognitive function in schizophrenia after one year of cognitive training and vocational services. Schizophrenia Research 2007, 96: 156-161. PMID: 17669629, PMCID: PMC2080620, DOI: 10.1016/j.schres.2007.07.003.Peer-Reviewed Original ResearchConceptsNeurocognitive enhancement therapyCognitive training exercisesCognitive remediation programNeuropsychological test batterySchizoaffective disorderCognitive trainingExecutive functionEnhancement therapyTest batteryCognitive functionCognitive deficitsRemediation programVocational programsCommunity mental health centerYear-long programMental health centersFeedback groupVocational servicesStable outpatientsParticipantsSchizophreniaTraining exercisesProcessing groupUrban community mental health centerSupport programsA pilot study of a weight management program with food provision in schizophrenia
Jean-Baptiste M, Tek C, Liskov E, Chakunta UR, Nicholls S, Hassan AQ, Brownell KD, Wexler BE. A pilot study of a weight management program with food provision in schizophrenia. Schizophrenia Research 2007, 96: 198-205. PMID: 17628437, DOI: 10.1016/j.schres.2007.05.022.Peer-Reviewed Original ResearchMeSH KeywordsAdultBlood GlucoseBody WeightEnergy IntakeExerciseFeeding BehaviorFemaleHumansMaleObesityPilot ProjectsPsychotic DisordersSample SizeSchizophreniaConceptsWeight lossSignificant medical risksMeaningful weight lossWeight loss programWeight management programSevere mental illnessSerious medical problemLifestyle modificationComorbid obesityLoss programPilot trialGeneral populationMetabolic indicesCognitive impairmentMental illnessMedical riskMedical problemsWeight gainObesityPilot studySpecific populationsSchizophreniaBehavioral programHealthy foodsReplacement program
2005
Neurocognitive enhancement therapy with work therapy: Productivity outcomes at 6- and 12-month follow-ups
Bell MD, Bryson GJ, Greig TC, Fiszdon JM, Wexler BE. Neurocognitive enhancement therapy with work therapy: Productivity outcomes at 6- and 12-month follow-ups. The Journal Of Rehabilitation Research And Development 2005, 42: 829. PMID: 16680620, DOI: 10.1682/jrrd.2005.03.0061.Peer-Reviewed Original ResearchMeSH KeywordsAdultCognitive Behavioral TherapyCombined Modality TherapyFollow-Up StudiesHumansMiddle AgedNeuropsychological TestsOdds RatioPatient ComplianceProbabilityPsychiatric Status Rating ScalesPsychotic DisordersRehabilitation, VocationalRisk AssessmentSchizophreniaTask Performance and AnalysisTime FactorsTreatment OutcomeConceptsNeurocognitive enhancement therapyWork therapyCognitive trainingEnhancement therapyComputerized cognitive trainingExecutive functionWork outcomesCommunity mental health centerDiagnosis of schizophreniaMental health centersMental hygiene clinicSchizoaffective disorderRandom effects analysisNet trainingProductivity outcomesTrainingRehabilitation programSchizophreniaMore hoursMemoryPresent studyDisordersOutcomesEffect analysisFindings
2001
Neurocognitive Enhancement Therapy With Work Therapy: Effects on Neuropsychological Test Performance
Bell M, Bryson G, Greig T, Corcoran C, Wexler BE. Neurocognitive Enhancement Therapy With Work Therapy: Effects on Neuropsychological Test Performance. JAMA Psychiatry 2001, 58: 763-768. PMID: 11483142, DOI: 10.1001/archpsyc.58.8.763.Peer-Reviewed Original ResearchMeSH KeywordsAdultAttentionCognitionCognition DisordersComputer-Assisted InstructionDichotic Listening TestsFeedbackFemaleFrontal LobeHumansMaleMemoryMultivariate AnalysisNeuropsychological TestsOccupational TherapyPsychomotor PerformancePsychotic DisordersSchizophreniaSchizophrenic PsychologyTeachingTreatment OutcomeConceptsNeurocognitive enhancement therapyEnhancement therapyWork therapyMental activityNeuropsychological testingLarge effect size improvementsExecutive function tasksNeuropsychological test performanceEffect size improvementsComputer-based trainingFunction tasksExecutive functionMemory performanceCognitive performanceNeuropsychological testsTraining tasksCognitive deficitsTest performanceComputer trainingCognitive dysfunctionIndependent outcome measureOccupational dysfunctionNatural contextSchizoaffective disorderMemory
1991
Cerebral laterality, symptoms, and diagnosis in psychotic patients
Wexler B, Giller E, Southwick S. Cerebral laterality, symptoms, and diagnosis in psychotic patients. Biological Psychiatry 1991, 29: 103-116. PMID: 1995082, DOI: 10.1016/0006-3223(91)90039-o.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBrainDepressive DisorderDichotic Listening TestsFunctional LateralityHumansMaleMiddle AgedProhibitinsPsychotic DisordersSchizophreniaConceptsRight ear advantageLower right-ear advantagesManic patientsPositive symptomsNegative symptomsCerebral lateralitySubset of patientsDisease-related decreaseWord TestSchizoaffective patientsSymptomatic inpatientsDepressed patientsHealthy controlsSymptom remissionSchizophrenic patientsMood disturbancePatientsMore symptomsPsychotic patientsSymptomsDichotic word testLeft hemisphereEar advantageThought disorderSimilar changes
1989
Possible Subtypes of Affective Disorder Suggested by Differences in Cerebral Laterality and Testosterone: A Preliminary Report
Wexler B, Mason J, Giller E. Possible Subtypes of Affective Disorder Suggested by Differences in Cerebral Laterality and Testosterone: A Preliminary Report. JAMA Psychiatry 1989, 46: 429-433. PMID: 2712661, DOI: 10.1001/archpsyc.1989.01810050043007.Peer-Reviewed Original ResearchConceptsSerum testosterone levelsDichotic listening testAffective disordersTestosterone levelsMean serum testosterone levelCerebral lateralityTime of admissionPathophysiological heterogeneityDiagnostic groupsSymptom severityPreliminary reportPossible subtypesHemisphere functionDisordersSubgroupsLateralityMeaningful subgroupsPositive correlationNegative correlationGroupHospitalizationPatientsAdmissionPathogenesesTestosterone
1986
Alterations in Cerebral Laterality during Acute Psychotic Illness
Wexler B. Alterations in Cerebral Laterality during Acute Psychotic Illness. The British Journal Of Psychiatry 1986, 149: 202-209. PMID: 3779276, DOI: 10.1192/bjp.149.2.202.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainFemaleFunctional LateralityHumansMaleMiddle AgedNeuropsychological TestsPrognosisPsychotic DisordersConceptsAcute psychotic illnessAcute psychotic episodeMajor psychiatric illnessDichotic listening testPsychiatric illnessPsychotic episodePsychotic illnessHemisphere dysfunctionLocalisation testsDot testCerebral lateralityNonsense Syllable TestIllnessWord TestTone testMedicationsPatientsPerceptual asymmetryDysfunctionDiagnosisA Model of Brain Function: Its Implications for Psychiatric Research
Wexler B. A Model of Brain Function: Its Implications for Psychiatric Research. The British Journal Of Psychiatry 1986, 148: 357-362. PMID: 3730703, DOI: 10.1192/bjp.148.4.357.Peer-Reviewed Original Research
1979
Alterations in Cerebral Laterality During Acute Psychotic Illness
Wexler B, Heninger G. Alterations in Cerebral Laterality During Acute Psychotic Illness. JAMA Psychiatry 1979, 36: 278-284. PMID: 33633, DOI: 10.1001/archpsyc.1979.01780030044003.Peer-Reviewed Original ResearchConceptsAcute psychotic illnessHigher lateralityCerebral lateralityPsychotic illnessPrimary major depressive illnessMajor depressive illnessDirect drug effectRight-handed patientsDichotic listening testDepressive illnessControl subjectsDegree of lateralizationNurses' ratingsClinical stateDrug effectsDiagnostic groupsPatientsLateralityIllnessInterindividual differencesPsychotic thoughtWeeksAccuracy of performanceLateralization