2014
Increasing stimulus duration can normalize late-positive event related potentials in people with schizophrenia: Possible implications for understanding cognitive deficits
Wexler BE, Ikezawa S, Corbera S. Increasing stimulus duration can normalize late-positive event related potentials in people with schizophrenia: Possible implications for understanding cognitive deficits. Schizophrenia Research 2014, 158: 163-169. PMID: 25096541, PMCID: PMC4240766, DOI: 10.1016/j.schres.2014.07.012.Peer-Reviewed Original ResearchConceptsHealthy controlsCognitive deficitsMs stimuliStructured Clinical InterviewDSM-IV criteriaModulation of responsesStimulus durationPictures of handsEvent Related PotentialsAdult outpatientsPain stimuliHealthy peoplePatientsClinical InterviewSchizoaffective disorderSchizophreniaMs stimulusSensory inputStimulus onsetSame durationDurationStimuliDeficitsResponseNeutral stimuli
2013
Emotion self-regulation and empathy depend upon longer stimulus exposure
Ikezawa S, Corbera S, Wexler BE. Emotion self-regulation and empathy depend upon longer stimulus exposure. Social Cognitive And Affective Neuroscience 2013, 9: 1561-1568. PMID: 24064924, PMCID: PMC4187273, DOI: 10.1093/scan/nst148.Peer-Reviewed Original ResearchConceptsLate positive potentialSelf-regulatory processesEvent-related potentialsEmpathic responsesLate event-related potentialsThreat-related stimuliPain-related stimuliLonger stimulus exposuresLate ERP componentsPictures of handsStimulus exposure durationAttentional modulationERP responsesERP componentsNeural basisBrain processingStimulus exposureTask conditionsStimulus presentationNeutral situationsProcessing existClinical populationsStimulus durationExposure durationJudgment condition
2012
A pilot and feasibility study of computer-based training for visual processing deficits in schizophrenia
Surti TS, Wexler BE. A pilot and feasibility study of computer-based training for visual processing deficits in schizophrenia. Schizophrenia Research 2012, 142: 248-249. PMID: 23043873, DOI: 10.1016/j.schres.2012.09.013.Peer-Reviewed Original Research
2011
Successful computer-based visual training specifically predicts visual memory enhancement over verbal memory improvement in schizophrenia
Surti TS, Corbera S, Bell MD, Wexler BE. Successful computer-based visual training specifically predicts visual memory enhancement over verbal memory improvement in schizophrenia. Schizophrenia Research 2011, 132: 131-134. PMID: 21795025, PMCID: PMC3195942, DOI: 10.1016/j.schres.2011.06.031.Peer-Reviewed Original ResearchConceptsCognitive remediationCognitive control trainingEarly visual processingVerbal memory improvementVerbal learningAuditory learningVisual learningCognitive gainsVisual processingMemory enhancementVisual trainingCognitive outcomesMemory improvementControl trainingNeuropsychological testingVisual informationMultiple modalitiesTraining exercisesLearningInformation manipulationTrainingSchizophreniaGeneralizesTaskParticipants
2005
Cue-Induced Brain Activity Changes and Relapse in Cocaine-Dependent Patients
Kosten TR, Scanley BE, Tucker KA, Oliveto A, Prince C, Sinha R, Potenza MN, Skudlarski P, Wexler BE. Cue-Induced Brain Activity Changes and Relapse in Cocaine-Dependent Patients. Neuropsychopharmacology 2005, 31: 644-650. PMID: 16123763, DOI: 10.1038/sj.npp.1300851.Peer-Reviewed Original ResearchConceptsFunctional magnetic resonance imagingPosterior cingulate cortexCocaine-related cuesCocaine-dependent patientsBrain activationTreatment effectiveness scoreSensory association corticesBrain activity changesPCC activationCocaine cuesSuperior temporalBOLD activationCingulate cortexSubjective reportsTreatment developmentAssociation cortexCuesProcessing areasCocaine abusePhysiological activationCortexNonrelapsersBest predictorCocaine-free urinesDrug use
2004
Functional MRI changes before and after onset of reported emotions
Prohovnik I, Skudlarski P, Fulbright RK, Gore JC, Wexler BE. Functional MRI changes before and after onset of reported emotions. Psychiatry Research 2004, 132: 239-250. PMID: 15664795, DOI: 10.1016/j.pscychresns.2004.03.005.Peer-Reviewed Original ResearchMeSH KeywordsAdultBrainEmotionsFemaleHumansMagnetic Resonance ImagingMaleMood DisordersPhotic StimulationTemporal LobeTime FactorsVideotape RecordingConceptsFunctional magnetic resonance imagingEmotional responsesConscious emotional experienceBrain regionsBrain-imaging studiesSubjective emotional responsesNegative emotional responsesFace social interactionsSuperior temporal gyrusMiddle frontal gyrusEmotion-related behaviorsDistinctive brain regionsMultiple brain regionsCognitive tasksEvoked emotionHealthy young adultsNeural correlatesSad conditionEmotional experienceFrontal gyrusReported onsetEmotional stimulationTemporal gyrusSensory regionsSocial interaction
1994
Decreased perceptual sensitivity to emotion-evoking stimuli in depression
Wexler B, Levenson L, Warrenburg S, Price L. Decreased perceptual sensitivity to emotion-evoking stimuli in depression. Psychiatry Research 1994, 51: 127-138. PMID: 8022947, DOI: 10.1016/0165-1781(94)90032-9.Peer-Reviewed Original ResearchConceptsFacial displaysOwn faceNegative emotion-related wordsEmotion-evoking stimuliEmotion-related wordsDichotic listening paradigmEmotion-related stimuliNegative facial displaysNormal cognitive processingNeutral wordsAutomatic mimicryCognitive processingPerceptual sensitivityFacial mimicryNegative wordsEmotional responsesDichotic testsSelective perceptionDepressed patientsStimuliWordsHealthy controlsEmotionsFaceSuch measures