2003
Increased leukocyte-platelet adhesion in patients with graft occlusion after peripheral vascular surgery
Esposito CJ, Popescu WM, Rinder HM, Schwartz JJ, Smith BR, Rinder CS. Increased leukocyte-platelet adhesion in patients with graft occlusion after peripheral vascular surgery. Thrombosis And Haemostasis 2003, 90: 1128-1134. PMID: 14652647, DOI: 10.1160/th03-04-0226.Peer-Reviewed Original ResearchConceptsPeripheral vascular diseasePeripheral vascular surgeryGraft occlusionLeukocyte-platelet adhesionOcclusion groupPlatelet turnoverVascular surgeryPMN activationPeripheral vascular surgery patientsLower extremity peripheral vascular diseaseEtiology of thrombosisVascular surgery patientsLate graft occlusionEarly postoperative periodSurface CD11b expressionProgression of atherosclerosisGraft lossPVD patientsGraft patientsPostoperative dayPostoperative periodSurgery patientsAcute thrombosisGraft patencyVascular disease
1999
Selective blockade of membrane attack complex formation during simulated extracorporeal circulation inhibits platelet but not leukocyte activation
Rinder CS, Rinder HM, Smith MJ, Tracey JB, Fitch J, Li L, Rollins SA, Smith BR. Selective blockade of membrane attack complex formation during simulated extracorporeal circulation inhibits platelet but not leukocyte activation. Journal Of Thoracic And Cardiovascular Surgery 1999, 118: 460-466. PMID: 10469960, DOI: 10.1016/s0022-5223(99)70183-2.Peer-Reviewed Original ResearchMeSH KeywordsAntibodies, MonoclonalBlood PlateletsComplement ActivationComplement C3aComplement C8Complement Membrane Attack ComplexEnzyme-Linked Immunosorbent AssayExtracorporeal CirculationFlow CytometryHumansLeukocyte CountLeukocyte ElastaseMacrophage-1 AntigenNeutrophil ActivationNeutrophilsPlatelet ActivationPlatelet CountP-SelectinReference ValuesConceptsNeutrophil activationExtracorporeal circuitExtracorporeal circulationLeukocyte activationMembrane attack complexPlatelet activationC5b-9C5b-9 generationAttack complexC5b-9 formationMembrane attack complex formationPlatelet CD62PControl circulationCardiopulmonary bypassLate complement componentsPlatelet countMonocyte countInhibits plateletSelective blockadeLoss of monocytesExtracorporeal modelSC5b-9Complement activationComplement componentsCellular activation
1994
Neutrophil but not Monocyte Activation Inhibits P-Selectin-Mediated Platelet Adhesion*
Rinder H, Tracey J, Rinder C, Leitenberg D, Smith B. Neutrophil but not Monocyte Activation Inhibits P-Selectin-Mediated Platelet Adhesion*. Thrombosis And Haemostasis 1994, 72: 750-756. PMID: 7534948, DOI: 10.1055/s-0038-1648953.Peer-Reviewed Original ResearchMeSH KeywordsCell Adhesion MoleculesHumansMonocytesNeutrophil ActivationPlatelet AdhesivenessPlatelet Membrane GlycoproteinsP-SelectinConceptsNeutrophil-platelet conjugatesP-selectinP-selectin-mediated platelet adhesionDREG-56Platelet activationL-selectinPlatelet P-selectin expressionP-selectin-expressing plateletsP-selectin-positive plateletsLeukocyte-platelet conjugatesNeutrophil-platelet adhesionPlatelet P-selectinP-selectin expressionWhole blood modelLeukocyte-platelet adhesionPlatelet adhesionNeutrophil activationLeukocyte activationNeutrophil adhesionBaseline levelsNeutrophilsUnstimulated leukocytesMonoclonal antibodiesEndothelial cellsImmediate rise