2015
Impact of Molecular Clonality on Survival in Acute Myeloid Leukemia
Schulz W, Durant T, Rinder H, Tormey C, Torres R, Smith B, Hager K, Howe J, Siddon A. Impact of Molecular Clonality on Survival in Acute Myeloid Leukemia. Blood 2015, 126: 1385. DOI: 10.1182/blood.v126.23.1385.1385.Peer-Reviewed Original ResearchDe novo acute myeloid leukemiaNovo acute myeloid leukemiaAcute myeloid leukemiaMolecular clonalityAML patientsTumor heterogeneityMyeloid leukemiaNext-generation sequencingNormal-risk subjectsAdverse prognostic indicatorTime of diagnosisFurther prospective studiesLong-term outcomesFLT3-ITD mutationHigh-risk groupChoice of therapyFirst prospective evidenceLimited clinical utilityHigh-risk classificationEarly survivalStudy patientsOverall survivalPatient agePatient subsetsInitial diagnosis
2006
Transcerebral Platelet Activation After Aortic Cross-Clamp Release is Linked to Neurocognitive Decline
Mathew JP, Rinder HM, Smith BR, Newman MF, Rinder CS. Transcerebral Platelet Activation After Aortic Cross-Clamp Release is Linked to Neurocognitive Decline. The Annals Of Thoracic Surgery 2006, 81: 1644-1649. PMID: 16631650, DOI: 10.1016/j.athoracsur.2005.12.070.Peer-Reviewed Original ResearchConceptsCross-clamp removalAortic cross-clamp removalCardiopulmonary bypassPlatelet activationNeurocognitive injuryCognitive deficitsNeurocognitive declineElective coronary artery bypass graft surgeryCoronary artery bypass graft surgeryAortic cross-clamp releaseArtery bypass graft surgeryBypass graft surgeryCross-clamp releaseSubset of patientsVenous blood samplesJugular venous blood samplesJugular venous bloodCPB patientsGraft surgeryCardiac surgeryPatient subsetsInjury scoreAortic archVenous bloodCognitive injury