Neutrophil but not Monocyte Activation Inhibits P-Selectin-Mediated Platelet Adhesion*
Rinder H, Tracey J, Rinder C, Leitenberg D, Smith B. Neutrophil but not Monocyte Activation Inhibits P-Selectin-Mediated Platelet Adhesion*. Thrombosis And Haemostasis 1994, 72: 750-756. PMID: 7534948, DOI: 10.1055/s-0038-1648953.Peer-Reviewed Original ResearchConceptsNeutrophil-platelet conjugatesP-selectinP-selectin-mediated platelet adhesionDREG-56Platelet activationL-selectinPlatelet P-selectin expressionP-selectin-expressing plateletsP-selectin-positive plateletsLeukocyte-platelet conjugatesNeutrophil-platelet adhesionPlatelet P-selectinP-selectin expressionWhole blood modelLeukocyte-platelet adhesionPlatelet adhesionNeutrophil activationLeukocyte activationNeutrophil adhesionBaseline levelsNeutrophilsUnstimulated leukocytesMonoclonal antibodiesEndothelial cellsImmediate risePlatelet-leukocyte activation and modulation of adhesion receptors in pediatric patients with congenital heart disease undergoing cardiopulmonary bypass
Rinder C, Gaal D, Student L, Smith B. Platelet-leukocyte activation and modulation of adhesion receptors in pediatric patients with congenital heart disease undergoing cardiopulmonary bypass. Journal Of Thoracic And Cardiovascular Surgery 1994, 107: 280-288. PMID: 8283897, DOI: 10.1016/s0022-5223(94)70482-1.Peer-Reviewed Original ResearchConceptsCongenital heart diseasePlatelet-leukocyte conjugatesNoncyanotic congenital heart diseaseCardiopulmonary bypassHeart diseasePediatric patientsNoncyanotic patientsLeukocyte activationPlatelet glycoprotein IbNeutrophil-platelet conjugatesPlatelet–leukocyte activationTermination of bypassCyanotic heart diseaseEnd of bypassMonocyte-platelet conjugatesGlycoprotein IbNoncyanotic heart diseaseActivation of plateletsInflammatory complicationsPulmonary dysfunctionCyanotic patientsPlatelet adhesion receptorsCD11b expressionClinical riskBaseline values