1999
Use of rituximab and irradiated donor-derived lymphocytes to control Epstein–Barr virus-associated lymphoproliferation in patients undergoing related haplo-identical stem cell transplantation
McGuirk J, Seropian S, Howe G, Smith B, Stoddart L, Cooper D. Use of rituximab and irradiated donor-derived lymphocytes to control Epstein–Barr virus-associated lymphoproliferation in patients undergoing related haplo-identical stem cell transplantation. Bone Marrow Transplantation 1999, 24: 1253-1258. PMID: 10642818, DOI: 10.1038/sj.bmt.1702052.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntibodies, MonoclonalAntibodies, Monoclonal, Murine-DerivedAntigens, ViralAntineoplastic AgentsBlood Component TransfusionBlood DonorsDNA, ViralGraft vs Host DiseaseHematologic NeoplasmsHematopoietic Stem Cell TransplantationHerpesvirus 4, HumanHumansImmunosuppression TherapyLymphocytesLymphoproliferative DisordersMalePolymerase Chain ReactionRituximabConceptsEpstein-Barr virus-associated lymphoproliferative disorderStem cell transplantationEBV DNA titersB cell populationsCell transplantationTherapeutic strategiesEpstein-Barr virus-associated lymphoproliferationHaplo-identical stem cell transplantationEffective alternative therapeutic strategyAllogeneic stem cell transplantationCourses of rituximabDonor-derived lymphocytesPost-transplant immunosuppressionMonoclonal B-cell populationCD20 monoclonal antibodyCell populationsAlternative therapeutic strategiesImmunosuppressive medicationsSevere GVHDHost diseaseLymphocyte infusionPost transplantFatal complicationCurative therapyLymphoproliferative disorders
1989
Hematopoiesis In Vitro Coexists With Natural Killer Lymphocytes
Niemeyer C, Sieff C, Smith B, Ault K, Nathan D. Hematopoiesis In Vitro Coexists With Natural Killer Lymphocytes. Blood 1989, 74: 2376-2382. DOI: 10.1182/blood.v74.7.2376.2376.Peer-Reviewed Original ResearchBlood NK cellsNatural killerNK cellsInterleukin-2Colony formationMarrow progenitorsInhibition of MyeloidK562 target cellsNatural killer lymphocytesCell populationsCD16 positive lymphocytesMarrow cell populationsPositive lymphocytesHematopoietic progenitor cellsKiller lymphocytesCell ratioProgenitor cell populationsLymphocytesTarget cellsProgenitor cellsCell sorterInhibitionHuman hematopoiesisDisparate findingsCell lineagesHematopoiesis in vitro coexists with natural killer lymphocytes.
Niemeyer C, Sieff C, Smith B, Ault K, Nathan D. Hematopoiesis in vitro coexists with natural killer lymphocytes. Blood 1989, 74: 2376-82. PMID: 2529928, DOI: 10.1182/blood.v74.7.2376.bloodjournal7472376.Peer-Reviewed Original ResearchConceptsBlood NK cellsNatural killerNK cellsInterleukin-2Colony formationMarrow progenitorsInhibition of MyeloidK562 target cellsNatural killer lymphocytesCell populationsCD16 positive lymphocytesMarrow cell populationsPositive lymphocytesHematopoietic progenitor cellsKiller lymphocytesCell ratioProgenitor cell populationsLymphocytesTarget cellsProgenitor cellsCell sorterInhibitionHuman hematopoiesisDisparate findingsCell lineages
1985
Natural killer lymphocytes in hairy cell leukemia: presence of phenotypically identifiable cells with defective functional activity.
Smith BR, Rosenthal DS, Ault KA. Natural killer lymphocytes in hairy cell leukemia: presence of phenotypically identifiable cells with defective functional activity. Experimental Hematology 1985, 13: 189-93. PMID: 3884356.Peer-Reviewed Original ResearchConceptsHairy cell leukemiaNK cellsNatural killerFluorescence-activated cell sorterNK activityNK functionCell leukemiaFunctional deficiencyNormal numbersPhenotypic NK cellsMajority of patientsStandard 51Cr releaseSevere functional deficiencyDefective functional activityK562 targetsNK populationPatientsSurface markersK562 cell lineFunctional activityCell populationsCell sorterCell linesLeukemiaIdentifiable cellsOrigin of cell populations after bone marrow transplantation. Analysis using DNA sequence polymorphisms.
Ginsburg D, Antin JH, Smith BR, Orkin SH, Rappeport JM. Origin of cell populations after bone marrow transplantation. Analysis using DNA sequence polymorphisms. Journal Of Clinical Investigation 1985, 75: 596-603. PMID: 3882761, PMCID: PMC423535, DOI: 10.1172/jci111736.Peer-Reviewed Original ResearchConceptsBone marrow transplantationMixed lymphohematopoietic chimerismMarrow transplantationFull engraftmentLeukemic relapseLymphohematopoietic chimerismDonor originSuccessful bone marrow transplantationSevere combined immunodeficiency syndromeFailure of engraftmentCombined immunodeficiency syndromeCell populationsParticular clinical valueDNA sequence polymorphism analysisHost originPatient's peripheral leukocytesGraft lossDonor marrowImmunodeficiency syndromePosttransplant lymphomaSuccessful engraftmentT cellsPolymorphism analysisPeripheral leukocytesClinical value
1983
Cells on microspheres: A new technique for flow cytometric analysis of adherent cells
Bloch D, Smith B, Ault K. Cells on microspheres: A new technique for flow cytometric analysis of adherent cells. Cytometry 1983, 3: 449-452. PMID: 6343013, DOI: 10.1002/cyto.990030611.Peer-Reviewed Original Research