2007
Monocyte Activation in On-Pump Versus Off-Pump Coronary Artery Bypass Surgery
Greilich PE, Brouse CF, Rinder HM, Jessen ME, Rinder CS, Eberhart RC, Whitten CW, Smith BR. Monocyte Activation in On-Pump Versus Off-Pump Coronary Artery Bypass Surgery. Journal Of Cardiothoracic And Vascular Anesthesia 2007, 22: 361-368. PMID: 18503922, DOI: 10.1053/j.jvca.2007.08.009.Peer-Reviewed Original ResearchConceptsPump CABG surgeryCABG surgeryMonocyte activationPump CABGPump Versus Off-Pump Coronary Artery Bypass SurgeryOff-pump coronary artery bypass surgeryPump coronary artery bypass graft surgeryCoronary artery bypass graft surgeryOff-pump CABG surgeryArtery bypass graft surgeryCoronary artery bypass surgeryMonocyte CD11b expressionPrimary CABG surgeryBypass graft surgeryArtery bypass surgerySystemic inflammatory responseVeterans Affairs hospitalInterleukin levelsSurgery warrantsGraft surgeryAdverse eventsBypass surgeryHeparin reversalPathophysiologic differencesAntifibrinolytic agents
2002
Platelet PlA2 Polymorphism and Platelet Activation Are Associated with Increased Troponin I Release after Cardiopulmonary Bypass
Rinder CS, Mathew JP, Rinder HM, Howe J, Fontes M, Crouch J, Pfau S, Patel P, Smith BR. Platelet PlA2 Polymorphism and Platelet Activation Are Associated with Increased Troponin I Release after Cardiopulmonary Bypass. Anesthesiology 2002, 97: 1118-1122. PMID: 12411794, DOI: 10.1097/00000542-200211000-00013.Peer-Reviewed Original ResearchConceptsTroponin I concentrationsPlatelet glycoprotein IIIaCardiopulmonary bypassPlA2 polymorphismPlA2 alleleI concentrationsMyocardial injuryGlycoprotein IIIaPlatelet activationElective coronary artery bypassHigher troponin I concentrationsPostoperative troponin I concentrationsTroponin IPerioperative myocardial injuryCoronary artery bypassProthrombotic risk factorsCardiopulmonary bypass surgerySevere myocardial injuryArtery bypassBypass surgeryPlatelet polymorphismsRisk factorsCardiovascular settingsPlA2 genotypeBypass