2019
0670 Sleep-Related Event Physiologic Timing for Triggering Nonsustained Ventricular Tachycardia: A Case-crossover Analysis
May A, May R, Bena J, Wang L, Monahan K, Stone K, Barrett-Connor E, Koo B, Winkelman J, Redline S, Mittleman M, Mehra R. 0670 Sleep-Related Event Physiologic Timing for Triggering Nonsustained Ventricular Tachycardia: A Case-crossover Analysis. Sleep 2019, 42: a267-a268. DOI: 10.1093/sleep/zsz067.668.Peer-Reviewed Original ResearchRespiratory eventsSleep-related eventsHazard periodOsteoporotic fracturesOdds ratioBidirectional case-crossover designPeriodic limb movementsRespiratory-related arousalsConditional logistic regressionCase-crossover analysisCase-crossover designPhysiologic timingVentricular tachycardiaNSVTNSVT episodesPhysiologic effectsPLMSOlder menStudy participantsMan studyLogistic regressionLimb movementsSleepControl periodConfidence intervals
2018
Restless legs syndrome and periodic limb movements during sleep in the Multi-Ethnic Study of Atherosclerosis
Doan TT, Koo BB, Ogilvie RP, Redline S, Lutsey PL. Restless legs syndrome and periodic limb movements during sleep in the Multi-Ethnic Study of Atherosclerosis. Sleep 2018, 41: zsy106. PMID: 29860522, PMCID: PMC6093310, DOI: 10.1093/sleep/zsy106.Peer-Reviewed Original ResearchConceptsRestless legs syndromePrevalence of RLSConcurrent restless legs syndromePeriodic limb movementsMulti-Ethnic StudyLegs syndromeObesity statusOdds of RLSLimb movementsPrevalence of PLMSCommunity-based sampleRace/ethnicityRLS symptomsClinical criteriaAdjusted modelPLMSStudy participantsPrevalenceOlder individualsCross-sectional dataAtherosclerosisSexSyndromeWhite participantsSleep
2016
Periodic leg movements during sleep: phenotype, neurophysiology, and clinical significance
Ferri R, Koo BB, Picchietti DL, Fulda S. Periodic leg movements during sleep: phenotype, neurophysiology, and clinical significance. Sleep Medicine 2016, 31: 29-38. PMID: 28341521, DOI: 10.1016/j.sleep.2016.05.014.Peer-Reviewed Original ResearchConceptsRestless legs syndromePeriodic leg movementsLeg movementsLeg motor activityLegs syndromePathophysiological correlatesClinical correlatesObjective findingsClinical significanceClinical conditionsNeurophysiologic aspectsCurrent evidencePLMSMotor phenomenaMotor activityAge groupsTypical phenotypeSleepRecent findingsCurrent knowledgeFurther researchCorrelatesFindingsPhenotypeScoringThe Restless Legs Syndrome - Depression Relationship: Effect Mediation by Disturbed Sleep and Periodic Limb Movements (P1.149)
Koo B, Blackwell T, Lee H, Stone K, Louis E, Redline S. The Restless Legs Syndrome - Depression Relationship: Effect Mediation by Disturbed Sleep and Periodic Limb Movements (P1.149). Neurology 2016, 86 DOI: 10.1212/wnl.86.16_supplement.p1.149.Peer-Reviewed Original Research
2015
Restless Legs Syndrome: Would You Like That with Movements or Without?
Koo B. Restless Legs Syndrome: Would You Like That with Movements or Without? Tremor And Other Hyperkinetic Movements 2015, 5: 316. DOI: 10.5334/tohm.280.Peer-Reviewed Original ResearchRestless legs syndromeDiagnosis of RLSRLS diagnosisPeriodic limb movementsSupplementary diagnostic criterionRLS sufferersLegs syndromeSubjective symptomsSleep disturbancesDiagnostic criteriaMotor phenomenaProper diagnosisPatients' descriptionsSensorimotor conditionsPLMSDiagnosisLimb movementsInvestigational levelsPathophysiologySyndromeSymptomsEpidemiologySleepPharmacology
2013
Sleep-Related Movement Disorders and Parasomnias
Koo B. Sleep-Related Movement Disorders and Parasomnias. 2013, 187-209. DOI: 10.1007/978-1-4614-9065-4_12.Peer-Reviewed Original Research
2008
α‐Melanocyte stimulating hormone and adrenocorticotropic hormone: An alternative approach when thinking about restless legs syndrome?
Koo BB, Feng P, Dostal J, Strohl KP. α‐Melanocyte stimulating hormone and adrenocorticotropic hormone: An alternative approach when thinking about restless legs syndrome? Movement Disorders 2008, 23: 1234-1242. PMID: 18464280, PMCID: PMC7350876, DOI: 10.1002/mds.22035.Peer-Reviewed Original ResearchConceptsSlow-wave sleep IIRestless legs syndromeAdrenocorticotropic hormoneAlpha-MSHParadoxical sleepLegs syndromeQuiet wakePathogenesis of RLSAlpha-melanocyte stimulating hormoneActive wakeMeasurement of sleepIntracerebral cannulaeIntracerebroventricular administrationSleep fragmentationNormal salineSleep latencyStimulating hormoneSleep architectureFragmented sleepOwn controlMotor activityRatsSleepLimb movementsHormone