2016
Periodic leg movements during sleep: phenotype, neurophysiology, and clinical significance
Ferri R, Koo BB, Picchietti DL, Fulda S. Periodic leg movements during sleep: phenotype, neurophysiology, and clinical significance. Sleep Medicine 2016, 31: 29-38. PMID: 28341521, DOI: 10.1016/j.sleep.2016.05.014.Peer-Reviewed Original ResearchConceptsRestless legs syndromePeriodic leg movementsLeg movementsLeg motor activityLegs syndromePathophysiological correlatesClinical correlatesObjective findingsClinical significanceClinical conditionsNeurophysiologic aspectsCurrent evidencePLMSMotor phenomenaMotor activityAge groupsTypical phenotypeSleepRecent findingsCurrent knowledgeFurther researchCorrelatesFindingsPhenotypeScoring
2008
α‐Melanocyte stimulating hormone and adrenocorticotropic hormone: An alternative approach when thinking about restless legs syndrome?
Koo BB, Feng P, Dostal J, Strohl KP. α‐Melanocyte stimulating hormone and adrenocorticotropic hormone: An alternative approach when thinking about restless legs syndrome? Movement Disorders 2008, 23: 1234-1242. PMID: 18464280, PMCID: PMC7350876, DOI: 10.1002/mds.22035.Peer-Reviewed Original ResearchConceptsSlow-wave sleep IIRestless legs syndromeAdrenocorticotropic hormoneAlpha-MSHParadoxical sleepLegs syndromeQuiet wakePathogenesis of RLSAlpha-melanocyte stimulating hormoneActive wakeMeasurement of sleepIntracerebral cannulaeIntracerebroventricular administrationSleep fragmentationNormal salineSleep latencyStimulating hormoneSleep architectureFragmented sleepOwn controlMotor activityRatsSleepLimb movementsHormone