2023
Development and validation of a model predicting mild stroke severity on admission using electronic health record data
Waddell K, Myers L, Perkins A, Sico J, Sexson A, Burrone L, Taylor S, Koo B, Daggy J, Bravata D. Development and validation of a model predicting mild stroke severity on admission using electronic health record data. Journal Of Stroke And Cerebrovascular Diseases 2023, 32: 107255. PMID: 37473533, DOI: 10.1016/j.jstrokecerebrovasdis.2023.107255.Peer-Reviewed Original ResearchConceptsInitial stroke severityStroke severityElectronic health record dataHealth record dataSevere strokeIschemic strokeStroke careSample patientsMortality risk stratificationRecord dataVeterans Affairs hospitalMild stroke severityMultiple logistic regressionObservational cohortStroke outcomeIndependent predictorsRisk stratificationEHR data elementsPrimary analysisLogistic regressionStrokeValidation sampleSeverityPotent modifierEHR data
2019
0670 Sleep-Related Event Physiologic Timing for Triggering Nonsustained Ventricular Tachycardia: A Case-crossover Analysis
May A, May R, Bena J, Wang L, Monahan K, Stone K, Barrett-Connor E, Koo B, Winkelman J, Redline S, Mittleman M, Mehra R. 0670 Sleep-Related Event Physiologic Timing for Triggering Nonsustained Ventricular Tachycardia: A Case-crossover Analysis. Sleep 2019, 42: a267-a268. DOI: 10.1093/sleep/zsz067.668.Peer-Reviewed Original ResearchRespiratory eventsSleep-related eventsHazard periodOsteoporotic fracturesOdds ratioBidirectional case-crossover designPeriodic limb movementsRespiratory-related arousalsConditional logistic regressionCase-crossover analysisCase-crossover designPhysiologic timingVentricular tachycardiaNSVTNSVT episodesPhysiologic effectsPLMSOlder menStudy participantsMan studyLogistic regressionLimb movementsSleepControl periodConfidence intervals
2018
Suicidal thought and behavior in individuals with restless legs syndrome
Para KS, Chow CA, Nalamada K, Kakade VM, Chilakamarri P, Louis ED, Koo BB. Suicidal thought and behavior in individuals with restless legs syndrome. Sleep Medicine 2018, 54: 1-7. PMID: 30529070, DOI: 10.1016/j.sleep.2018.09.019.Peer-Reviewed Original ResearchConceptsRestless legs syndromeInternational RLS Study Group Severity ScaleLifetime suicidal ideationLifetime depression historySuicidal ideationDepression historyLegs syndromeControl participantsBrief Lifetime Depression ScaleCambridge-Hopkins RLS questionnairePotential demographic confoundersRisk of suicideStepwise logistic regressionRLS sufferersRLS questionnaireRLS diagnosisRLS severityDepression ScaleSuicidal Behaviors QuestionnaireLifetime depressionSeverity ScaleDemographic confoundersSuicidal thoughtsLogistic regressionDepression1015 Frequent Periodic Limb Movements During Sleep and Risk of Incident Stroke
May A, Koo B, Yaffe K, Leng Y, Cawthon P, Redline S, Stone K, Mehra R. 1015 Frequent Periodic Limb Movements During Sleep and Risk of Incident Stroke. Sleep 2018, 41: a376-a377. DOI: 10.1093/sleep/zsy061.1014.Peer-Reviewed Original ResearchBody mass indexIncident stroke riskPeriodic limb movementsStroke riskIncident strokeMulti-center prospective studyLimb movementsApnea-hypopnea indexAF findingsHypopnea indexMedian ageMedication useTotal cholesterolMass indexSleep apneaArousal indexProspective studyAutonomic dysregulationPhysical activityPLMSSignificant interactionStrokeLogistic regressionAlcohol useAgeDemoralization in Parkinson disease
Koo BB, Chow CA, Shah DR, Khan FH, Steinberg B, Derlein D, Nalamada K, Para KS, Kakade VM, Patel AS, de Figueiredo JM, Louis ED. Demoralization in Parkinson disease. Neurology 2018, 90: e1613-e1617. PMID: 29618626, PMCID: PMC5931805, DOI: 10.1212/wnl.0000000000005425.Peer-Reviewed Original ResearchConceptsDisease Rating ScaleParkinson's diseasePD cohortPatient Health Questionnaire-9 scoreOutpatient movement disorder clinicYounger ageUnified Parkinson's Disease Rating ScaleParkinson's Disease Rating ScaleMovement Disorders ClinicPart III scoreStepwise logistic regressionOverall cohortMotor dysfunctionDisorders ClinicDiagnostic criteriaTreatment approachesScale scoreLogistic regressionRating ScaleCohortControl participantsMarital statusPsychosomatic researchDepressed individualsDepression